| Entry |
|
|---|
| Name |
Orphenadrine hydrochloride;
Disipal (TN) |
|---|
| Formula |
C18H23NO. HCl
|
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| Exact mass |
305.1546
|
|---|
| Mol weight |
305.84
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
|
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| Remark |
| Product (DG01252): | D00774<US> |
|
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| Efficacy |
Skeletal muscle relaxant, Muscarinic acetylcholine receptor antagonist, H1 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AB Ethers chemically close to antihistamines
N04AB02 Orphenadrine (chloride)
D02599 Orphenadrine hydrochloride
USP drug classification [BR:br08302]
Skeletal Muscle Relaxants
Orphenadrine
D02599 Orphenadrine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01252 Orphenadrine
D02599 Orphenadrine hydrochloride
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
DG01252 Orphenadrine
D02599 Orphenadrine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D02599 Orphenadrine hydrochloride
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN (NMDAR)
D02599 Orphenadrine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01252 Orphenadrine
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
DG01252 Orphenadrine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 21
1 X Cl 41.4554 -19.1198
2 C1a C 30.9280 -20.7988
3 N1c N 32.1419 -20.0980
4 C1b C 33.3557 -20.7988
5 C1b C 34.5696 -20.0980
6 O2a O 35.7834 -20.7988
7 C1c C 36.9972 -20.0980
8 C8y C 38.2111 -20.7988
9 C8y C 36.9972 -18.6965
10 C8x C 38.1983 -18.0030
11 C8x C 38.1982 -16.6013
12 C8x C 36.9843 -15.9006
13 C8x C 35.7833 -16.5941
14 C8y C 35.7834 -17.9958
15 C8x C 38.2111 -22.2005
16 C8x C 39.4250 -22.9013
17 C8x C 40.6389 -22.2005
18 C8x C 40.6389 -20.7988
19 C8x C 39.4250 -20.0980
20 C1a C 34.5737 -18.6943
21 C1a C 32.1419 -18.6964
BOND 21
1 2 3 1
2 3 4 1
3 4 5 1
4 5 6 1
5 6 7 1
6 7 8 1
7 7 9 1
8 9 10 2
9 10 11 1
10 11 12 2
11 12 13 1
12 13 14 2
13 9 14 1
14 8 15 1
15 15 16 2
16 16 17 1
17 17 18 2
18 18 19 1
19 8 19 2
20 14 20 1
21 3 21 1
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