| Entry |
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| Name |
Diphenhydramine salicylate (JAN) |
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| Formula |
C17H21NO. C7H6O3
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| Exact mass |
393.1940
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| Mol weight |
393.47
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| Structure |
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| Simcomp |
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
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| Remark |
| Product (DG00390): | D00300<JP> D00669<JP/US> D00520<JP/US> |
| Product (mixture): | D04261<JP> D04425<JP> D08695<JP> |
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| Efficacy |
Antiallergic, Antivertigo, H1 receptor antagonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07212 | Histamine H1 receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA32 Diphenhydramine
D02419 Diphenhydramine salicylate (JAN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA02 Diphenhydramine
D02419 Diphenhydramine salicylate (JAN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for nervous and sensory systems
06 Antivertigo drugs (incl. motion/morning sickness remedies)
D02419 Diphenhydramine salicylate (JAN)
Allergic agents
52 Antihistamine based drugs
D02419 Diphenhydramine salicylate (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Diphenhydramine
D02419 Diphenhydramine salicylate (JAN)
Third-class OTC drugs
Inorganic and organic chemicals
Diphenhydramine
D02419 Diphenhydramine salicylate (JAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00390 Diphenhydramine
D02419 Diphenhydramine salicylate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D02419 Diphenhydramine salicylate (JAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00390 Diphenhydramine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C8y C 35.4176 -17.2194
2 C8y C 36.6305 -17.9191
3 C8x C 34.2047 -17.9191
4 C6a C 35.4176 -15.8198
5 C8x C 36.6305 -19.3186
6 O1a O 37.8433 -17.2194
7 C8x C 34.2047 -19.3186
8 O6a O 36.6305 -15.1201
9 O6a O 34.2047 -15.1201
10 C8x C 35.4176 -20.0183
11 C1c C 26.8347 -17.2856
12 C8y C 25.6239 -17.9899
13 C8y C 28.0515 -17.9899
14 O2a O 26.8406 -15.8884
15 C8x C 25.6239 -19.3930
16 C8x C 24.4130 -17.2856
17 C8x C 28.0458 -19.3930
18 C8x C 29.2565 -17.2856
19 C1b C 28.0515 -15.1840
20 C8x C 24.4130 -20.0856
21 C8x C 23.1962 -17.9899
22 C8x C 29.2565 -20.0856
23 C8x C 30.4732 -17.9899
24 C8x C 23.1962 -19.3930
25 C8x C 30.4673 -19.3930
26 C1b C 29.2874 -15.8950
27 N1c N 30.4839 -15.2016
28 C1a C 31.6732 -15.8857
29 C1a C 30.4817 -13.7927
BOND 30
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 4 9 2
9 5 10 1
10 7 10 2
11 15 20 2
12 16 21 1
13 17 22 1
14 18 23 2
15 20 24 1
16 22 25 2
17 21 24 2
18 23 25 1
19 11 12 1
20 11 13 1
21 11 14 1
22 12 15 1
23 12 16 2
24 13 17 2
25 13 18 1
26 14 19 1
27 19 26 1
28 26 27 1
29 27 28 1
30 27 29 1
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