| Entry |
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| Name |
Rebamipide (JP18/INN);
Mucosta (TN) |
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| Formula |
C19H15ClN2O4
|
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| Exact mass |
370.0720
|
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| Mol weight |
370.78
|
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| Structure |
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| Class |
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG02008 Gastric mucosal protectant
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
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| Remark |
|
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| Efficacy |
Anti-ulcerative, Mucin production accelerator |
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BX Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
A02BX14 Rebamipide
D01121 Rebamipide (JP18/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D01121 Rebamipide (JP18/INN)
2 Agents affecting individual organs
23 Digestive organ agents
232 Peptic ulcer agents
2329 Others
D01121 Rebamipide (JP18/INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG02008 Gastric mucosal protectant
D01121 Rebamipide
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D01121 Rebamipide
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01121 Rebamipide
D01121 Rebamipide tablets
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D01121
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C8x C 18.6833 -23.6491
2 C8x C 18.6833 -22.2477
3 C8x C 19.8999 -21.5470
4 C8x C 19.8999 -24.3498
5 C8y C 21.0393 -23.6491
6 C8y C 21.1034 -22.2477
7 C8y C 22.3140 -21.5417
8 C8x C 23.5306 -22.2373
9 C8y C 23.5366 -23.6387
10 N4x N 22.3259 -24.3446
11 O5x O 24.7532 -24.3342
12 C1b C 22.3081 -20.1403
13 C1c C 23.5174 -19.4449
14 N1b N 24.7277 -20.1456
15 C5a C 25.9380 -19.4449
16 C8y C 27.1483 -20.1456
17 C8x C 28.3603 -19.4477
18 C8x C 29.5707 -20.1485
19 C8y C 29.5690 -21.5470
20 C8x C 28.3569 -22.2448
21 C8x C 27.1466 -21.5441
22 X Cl 30.7818 -22.2491
23 O5a O 25.9380 -18.0434
24 C6a C 23.5194 -18.0434
25 O6a O 22.3067 -17.3409
26 O6a O 24.7342 -17.3444
BOND 28
1 2 3 1
2 12 13 1
3 3 6 2
4 13 14 1
5 5 4 2
6 14 15 1
7 4 1 1
8 15 16 1
9 5 6 1
10 6 7 1
11 7 8 2
12 8 9 1
13 9 10 1
14 16 17 2
15 17 18 1
16 18 19 2
17 19 20 1
18 20 21 2
19 21 16 1
20 10 5 1
21 19 22 1
22 15 23 2
23 9 11 2
24 13 24 1
25 1 2 2
26 24 25 1
27 7 12 1
28 24 26 2
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