| Entry |
|
|---|
| Name |
Betahistine mesilate (JP18);
Suzutolon (TN) |
|---|
| Formula |
(CH4SO3)2. C8H12N2
|
|---|
| Exact mass |
328.0763
|
|---|
| Mol weight |
328.41
|
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| Structure |
|
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
|
|---|
| Remark |
| Therapeutic category: | 1339 |
| Product (DG01004): | D01592<JP> |
|
|---|
| Efficacy |
Antivertigo, Vasodilator, Antihistaminic |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07C ANTIVERTIGO PREPARATIONS
N07CA Antivertigo preparations
N07CA01 Betahistine
D01592 Betahistine mesilate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
133 Vertigo agents
1339 Others
D01592 Betahistine mesilate (JP18)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
DG01004 Betahistine
D01592 Betahistine mesilate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D01592 Betahistine mesilate (JP18) <JP>
HRH3
D01592 Betahistine mesilate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01592 Betahistine mesilate
D01592 Betahistine mesilate tablets
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
DG01004 Betahistine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 20
1 S4a S 31.4297 -18.3999
2 O1d O 31.4368 -16.9981
3 O1d O 31.4368 -19.8017
4 C1a C 30.0279 -18.3999
5 O1d O 32.8316 -18.3999
6 C8x C 27.0676 -18.9723
7 C8x C 27.0676 -17.5705
8 N5x N 25.8507 -16.8695
9 C8y C 24.6409 -17.5705
10 C8x C 24.6409 -18.9723
11 C8x C 25.8507 -19.6732
12 C1b C 23.4356 -16.8764
13 C1b C 22.2250 -17.5774
14 N1b N 21.0143 -16.8836
15 C1a C 19.8036 -17.5846
16 S4a S 31.4297 -18.3999
17 C1a C 30.0279 -18.3999
18 O1d O 32.8316 -18.3999
19 O1d O 31.4368 -16.9981
20 O1d O 31.4368 -19.8017
BOND 18
1 6 7 2
2 7 8 1
3 8 9 2
4 9 10 1
5 10 11 2
6 11 6 1
7 9 12 1
8 12 13 1
9 13 14 1
10 14 15 1
11 1 4 1
12 1 5 1
13 1 2 2
14 1 3 2
15 16 17 1
16 16 18 1
17 16 19 2
18 16 20 2
BRACKET 1 28.3500 -20.0900 28.3500 -16.3800
1 34.2300 -16.3800 34.2300 -20.0900
1 2
ORIGINAL 1 1 4 5 2 3
REPEAT 1 16 17 18 19 20
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