Entry
Name
succinyl-CoA:cyclohexane-1-carboxylate CoA transferase;
Gmet_3304 (locus name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
succinyl-CoA---cyclohexane-1-carboxylate CoA-transferase
Reaction(IUBMB)
succinyl-CoA + cyclohexane-1-carboxylate = succinate + cyclohexane-1-carbonyl-CoA [RN:
R13299 ]
Reaction(KEGG)
Substrate
succinyl-CoA [CPD:
C00091 ];
cyclohexane-1-carboxylate [CPD:
C09822 ]
Product
succinate [CPD:
C00042 ];
cyclohexane-1-carbonyl-CoA [CPD:
C09823 ]
Comment
The enzyme, characterized from the bacterium Geobacter metallireducens, participates in an anaerobic degradation pathway for cyclohexane-1-carboxylate. In vitro, the enzyme can use butanoyl-coA as a CoA donor with greater efficiency than succinyl-CoA.
History
EC 2.3.1.315 created 2024
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K27540 succinyl-CoA:cyclohexane-1-carboxylate CoA transferase
Genes
Taxonomy
Reference
Authors
Kung JW, Meier AK, Mergelsberg M, Boll M.
Title
Enzymes involved in a novel anaerobic cyclohexane carboxylic acid degradation pathway.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.3.1.315
LinkDB
All DBs