KEGG ENZYME: 2.1.4.3

ENZYME: 2.1.4.3

Entry

EC 2.1.4.3                  Enzyme

Name

L-arginine:L-lysine amidinotransferase;
amtA (gene name)

Class

Transferases;
Transferring one-carbon groups;
Amidinotransferases

Sysname

L-arginine:L-lysine amidinotransferase

Reaction(IUBMB)

L-arginine + L-lysine = L-ornithine + L-homoarginine [RN:R12506]

Reaction(KEGG)

R12506

Substrate

L-arginine [CPD:C00062];
L-lysine [CPD:C00047]

Product

L-ornithine [CPD:C00077];
L-homoarginine [CPD:C01924]

Comment

The enzyme, characterized from the bacterium Pseudomonas savastanoi pv. phaseolicola, is involved in the biosynthesis of the toxin phaseolotoxin, a modified tripeptide that causes the 'halo blight' disease of beans.

History

EC 2.1.4.3 created 2019

Reference

1 [PMID:11310742]

Authors

Hernandez-Guzman G, Alvarez-Morales A

Title

Isolation and characterization of the gene coding for the amidinotransferase involved in the biosynthesis of phaseolotoxin in Pseudomonas syringae pv. phaseolicola.

Journal

Mol Plant Microbe Interact 14:545-54 (2001)
DOI:10.1094/MPMI.2001.14.4.545

Sequence

[psp:PSPPH_4303]

Reference

2 [PMID:27419063]

Authors

Li M, Chen L, Deng Z, Zhao C

Title

Characterization of AmtA, an amidinotransferase involved in the biosynthesis of phaseolotoxins.

Journal

FEBS Open Bio 6:603-9 (2016)
DOI:10.1002/2211-5463.12071