Entry
Name
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase;
kdnA (gene name)
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + 2-oxoglutarate = 8-dehydro-3-deoxy-alpha-D-manno-octulosonate + L-glutamate
Reaction(KEGG)
Substrate
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate;
2-oxoglutarate [CPD:
C00026 ]
Product
8-dehydro-3-deoxy-alpha-D-manno-octulosonate;
L-glutamate [CPD:
C00025 ]
Comment
The enzyme, characterized from the bacterium Shewanella oneidensis, forms 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. cf. EC
1.1.3.48 , 3-deoxy-alpha-D-manno-octulosonate 8-oxidase.
History
EC 2.6.1.109 created 2015
Orthology
K19715 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase
Genes
SCAA : TUM17387_18780(kdnA)
TIB : THMIRHAM_22010(kdnA)
TZO : THMIRHAT_01680(kdnA)
PHG : KCTC32516_02299(kdnA)
AALG : AREALGSMS7_04131(kdnA)
KOS : KORDIASMS9_03070(kdnA)
KAN : IMCC3317_45580(kdnA)
SPON : HME9304_03325(wbpE)
» show all
Taxonomy
Reference
Authors
Gattis SG, Chung HS, Trent MS, Raetz CR
Title
The origin of 8-amino-3,8-dideoxy-D-manno-octulosonic acid (Kdo8N) in the lipopolysaccharide of Shewanella oneidensis.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.6.1.109