Entry
Name
15,16-dihydrobiliverdin:ferredoxin oxidoreductase;
PebA
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With an iron-sulfur protein as acceptor
BRITE hierarchy
Sysname
15,16-dihydrobiliverdin:ferredoxin oxidoreductase
Reaction(IUBMB)
15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXalpha + reduced ferredoxin [RN:
R05818 ]
Reaction(KEGG)
Substrate
15,16-dihydrobiliverdin [CPD:
C11630 ];
oxidized ferredoxin [CPD:
C00139 ]
Product
biliverdin IXalpha;
reduced ferredoxin [CPD:
C00138 ]
Comment
Catalyses the two-electron reduction of biliverdin IXalpha at the C15 methine bridge. It has been proposed that this enzyme and EC
1.3.7.3 , phycoerythrobilin:ferredoxin oxidoreductase, function as a dual enzyme complex in the conversion of biliverdin IXalpha into phycoerythrobilin.
History
EC 1.3.7.2 created 2002
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
K05369 15,16-dihydrobiliverdin:ferredoxin oxidoreductase
Genes
SYR : SynRCC307_2061(pebA)
SYX : SynWH7803_0482(pebA)
SYH : Syncc8109_0441(pebA)
SYNW : SynWH8103_02324(pebA)
CWA : CwatDRAFT_0676 CwatDRAFT_2853
PRUN : PCC7821_02376(pebA)
» show all
Taxonomy
Reference
Authors
Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC.
Title
Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.3.7.2
ExPASy - ENZYME nomenclature database: 1.3.7.2
BRENDA, the Enzyme Database: 1.3.7.2