KEGG ENZYME: 1.3.7.13

ENZYME: 1.3.7.13

Entry

EC 1.3.7.13                 Enzyme

Name

3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin);
bciB (gene name);
cyano-type divinyl chlorophyllide a 8-vinyl-reductase

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With an iron-sulfur protein as acceptor

Sysname

protochlorophyllide-a:ferredoxin C-81-oxidoreductase

Reaction(IUBMB)

protochlorophyllide a + 2 oxidized ferredoxin [iron-sulfur] cluster = 3,8-divinyl protochlorophyllide a + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ [RN:R11519]

Reaction(KEGG)

R11519

Substrate

protochlorophyllide a [CPD:C02880];
oxidized ferredoxin [iron-sulfur] cluster [CPD:C00139]

Product

3,8-divinyl protochlorophyllide a [CPD:C11831];
reduced ferredoxin [iron-sulfur] cluster [CPD:C00138];
H+ [CPD:C00080]

Comment

The enzyme, found in many phototrophic bacteria, land plants, and some green and red algae, is involved in the production of monovinyl versions of (bacterio)chlorophyll pigments from their divinyl precursors. Binds two [4Fe-4S] clusters and an FAD cofactor. It can also act on 3,8-divinyl chlorophyllide a, 3,8-divinyl chlorophyll a, and chlorophyll c2. cf. EC 1.3.1.75, 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH).

History

EC 1.3.7.13 created 2016

Pathway

ec00860

Porphyrin metabolism

ec01100

Metabolic pathways

Orthology

K21231

3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin)

Genes

ALV:	Alvin_1181

ATEP:

Atep_13950

TVI:	Thivi_1847

MPUR:

MARPU_13415

TSY:	THSYN_32255

TTP:	E6P07_07490

CJAP:

GWK36_08640

THIM:

KFB96_20300

TBOG:

LT988_15460

TLR:	Thiosp_02229

TFRI:

Thiofri_01984

TWG:	Thiowin_01546

CTM:	Cabther_B0079

CVL:	J8C06_12185

CHLO:

J8C02_13070

CPH:	Cpha266_0188 Cpha266_0696

CLI:	Clim_0952 Clim_1791

PPH:

Ppha_2739

PAA:

Paes_0603

PROS:

CHL67_08655

PROW:

OO006_09735

PROI:

OO005_08955

CTS:

Ctha_1208

SYN:

slr1923

SYZ:	MYO_120210

SYY:	SYNGTS_2003(slr1923)

SYT:	SYNGTI_2002(slr1923)

SYS:	SYNPCCN_2001(slr1923)

SYQ:	SYNPCCP_2001(slr1923)

SYJ:	D082_17500

SYO:	C7I86_10445

SYNH:

HTZ78_05270

SYNS:

OLK001_14370

SYC:

syc0195_d

SYU:	M744_09820

SYF:	Synpcc7942_1359

SYR:	SynRCC307_0774(frhB)

SYX:	SynWH7803_1550(frhB)

CYA:

CYA_1215

CYB:

CYB_1261

SYNE:

Syn6312_0084

SYNP:

Syn7502_00002

SYNC:

CB0101_12805

SYNY:

BM449_02325

SYNZ:

H8F24_11360

SYNL:

KJJ24_07170

SYNO:

LY254_04185

DSL:	Dacsa_2505

CGC:	Cyagr_0231

CYI:	CBM981_1201

WNA:	KA717_07075

CMP:	Cha6605_2982

CYN:	Cyan7425_2254

CEP:	Cri9333_0217

TVN:	NIES2134_117710

SLW:	BRW62_08195

TEL:

tll1845

THN:	NK55_05905(cvrA)

THEC:

FFX45_08395

THEY:

JW907_00965

TSQ:	D3A95_10825

AMR:	AM1_2849(frhB)

ACAM:

HRE53_11305

TSZ:	OOK60_05170

LEN:	LEP3755_15190

LET:	O77CONTIG1_04225

LBO:	LBWT_11590

LEPB:

GFS31_33060

KOV:	K9N68_33530

LSC:	KIK02_10155

LSK:	J5X98_02715

HHG:	XM38_013900

PSEU:

Pse7367_0632

PSER:

ABRG53_0874

PGX:	OA858_21850

THEU:

HPC62_06265

TOG:	HNI00_15000

TSIN:

OXH18_07000

GLP:	Glo7428_1172

CHON:

NIES4102_39060

GDU:	P0S91_14025

GEN:	GM3709_977

GEE:	GM3708_3044

CAN:	Cyan10605_0476

CSN:	Cyast_1162

CYL:	AA637_09240(frhB)

SYP:	SYNPCC7002_A2638(fruB)

SYV:	AWQ23_13150

SYL:	AWQ21_13320

SYNN:

NIES970_06210(fruB)

PIP:	FEK30_02865

MAR:

MAE_40060

MIQ:	B5D77_12980

MVZ:	myaer102_14830

HAO:	PCC7418_0506

ENN:	FRE64_15320

CYT:

cce_4662

CWA:	CwatDRAFT_5144

CYP:	PCC8801_1364

CYH:	Cyan8802_1394

CYC:	PCC7424_0101

CYJ:	Cyan7822_1352

TER:

Tery_0742

ARP:	NIES39_B00910

PAGH:

NIES204_39540

PPSU:

NO713_01543

PRUN:

PCC7821_04709

MVAG:

D0A34_03045

LFS:	HFV01_07105

LIX:	H2674_18675

OXY:	HCG48_07140

OAC:	Oscil6304_5624

ONI:	Osc7112_3795

MPRO:

BJP34_26410

PHOR:

JWS08_19460

PYH:	NEA10_14725

MIC:	Mic7113_6152

GEI:	GEI7407_0463

GVI:	gll0878 glr2543

GLJ:	GKIL_2429(frhB) GKIL_4087(frhB)

GML:	ISF26_18540 ISF26_22815

ANA:

all1601

NPU:	Npun_R5367

NOS:	Nos7107_0620

NOP:	Nos7524_4753

NON:	NOS3756_14520

NFL:	COO91_08888

NOE:	CLI64_08240

NSH:

GXM_03620

NED:	HUN01_32670

NPZ:	ACX27_26490

NLK:	NIES25_58690

NCW:	NIES2107_57340

NCF:	ANSO36C_62300

AVA:

Ava_4214

NAZ:

Aazo_3552

ANB:	ANA_C20199

ACY:	Anacy_4773

AWA:	AA650_16785

ANN:	EH233_10975

CSG:	Cylst_2678

RSIN:

B6N60_02674

HBQ:	QI031_00965

CALO:

Cal7507_2596

CALT:

Cal6303_5470

CALH:

IJ00_05065

CALN:

NIES2098_27930

CALS:

NIES3974_27740

RIV:	Riv7116_3544

MDP:	NIES3275_51800

FIS:	FIS3754_38180

NSPH:

BDGGKGIB_02544

DOU:	BMF77_00176

DFS:	HGD76_17220

DHT:	NG743_21955

DCM:	NIES806_39450

DOT:	EZY12_14715

DOZ:	HEP80_16960

DOC:	HEQ26_16095

CCUR:

IAR63_05415

CRK:	L3I90_06330

AFLO:

HEQ12_18900

STOQ:

K2F26_06495

SKV:	NIES73_23240

AEE:	IM676_07000

RCS:	NIES932_16790

OCF:	WJM97_21030

TOQ:	HCG51_19375

TTQ:	NIES37_04640

ALAX:

NIES50_15200

SCYT:

SAMD_13340

SCYS:

NIES4073_83220

BSEN:

DP114_30540

BOX:	DP113_30680

NCN:	BZZ01_14775

CTHE:

Chro_1099

PLP:	Ple7327_2676

SCS:	Sta7437_0582

STAN:

STA3757_21750

GLT:	GlitD10_1704(frhB)

GCY:	LQF76_14005

CAU:

Caur_2555

CHL:	Chy400_2759

CAG:

Cagg_3479

CALL:

OZ401_000873

» show all

Reference

1 [PMID:17148453]

Authors

Chew AG, Bryant DA

Title

Characterization of a plant-like protochlorophyllide a divinyl reductase in green sulfur bacteria.

Journal

J Biol Chem 282:2967-75 (2007)
DOI:10.1074/jbc.M609730200

Reference

2 [PMID:24151992]

Authors

Saunders AH, Golbeck JH, Bryant DA

Title

Characterization of BciB: a ferredoxin-dependent 8-vinyl-protochlorophyllide reductase from the green sulfur bacterium Chloroherpeton thalassium.

Journal

Biochemistry 52:8442-51 (2013)
DOI:10.1021/bi401172b

Sequence

[cts:Ctha_1208]

Reference

3 [PMID:24399236]

Authors

Ito H, Tanaka A

Title

Evolution of a new chlorophyll metabolic pathway driven by the dynamic changes in enzyme promiscuous activity.

Journal

Plant Cell Physiol 55:593-603 (2014)
DOI:10.1093/pcp/pct203

Sequence

[syn:slr1923]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.7.13

IUBMB Enzyme Nomenclature:

1.3.7.13

ExPASy - ENZYME nomenclature database:

1.3.7.13

BRENDA, the Enzyme Database:

1.3.7.13

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (374)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (190)   
   KEGG MGENES (129)   
   RefGene (54)   
All databases (385)   

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