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KEGG   Zalophus californianus (California sea lion): 113939775
Entry
113939775         CDS       T07874                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca04010  MAPK signaling pathway
zca04015  Rap1 signaling pathway
zca04218  Cellular senescence
zca04620  Toll-like receptor signaling pathway
zca04664  Fc epsilon RI signaling pathway
zca04668  TNF signaling pathway
zca04714  Thermogenesis
zca04750  Inflammatory mediator regulation of TRP channels
zca04912  GnRH signaling pathway
zca04935  Growth hormone synthesis, secretion and action
zca04936  Alcoholic liver disease
zca05014  Amyotrophic lateral sclerosis
zca05022  Pathways of neurodegeneration - multiple diseases
zca05132  Salmonella infection
zca05135  Yersinia infection
zca05145  Toxoplasmosis
zca05161  Hepatitis B
zca05169  Epstein-Barr virus infection
zca05170  Human immunodeficiency virus 1 infection
zca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
zca05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    113939775 (MAP2K3)
   04668 TNF signaling pathway
    113939775 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    113939775 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    113939775 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    113939775 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113939775 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    113939775 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113939775 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    113939775 (MAP2K3)
   05161 Hepatitis B
    113939775 (MAP2K3)
   05169 Epstein-Barr virus infection
    113939775 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    113939775 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    113939775 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    113939775 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    113939775 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113939775 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    113939775 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:zca01001]
    113939775 (MAP2K3)
Enzymes [BR:zca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     113939775 (MAP2K3)
Protein kinases [BR:zca01001]
 Serine/threonine kinases: STE group
  STE7 family
   113939775 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 113939775
NCBI-ProteinID: XP_027482150
UniProt: A0A6J2FQ34
Position
16:13059645..13088569
AA seq 347 aa
MESPASSQPASMPQTKGKSKRKKDIRISFVSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHNQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctccagtcagcccgccagcatgccccagaccaaagggaaatccaaa
aggaagaaggatatacggatatccttcgtgtccaagccgcccgtacccaaccccacaccc
ccccggaaccttgactctcggaccttcatcaccatcggagacaggaactttgaggtggag
gctgatgacctggtgaccatctcggagctgggccgtggggcctacggggtggtggagaag
gtgcggcataaccagagtggcaccatcatggctgttaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcgtacggttgactgc
ttctacaccgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgcttgataaaaacatgacc
attccagaggacatcctgggggaaattgctgtgtctatcgtgagggcgctggagcatctg
cacagcaagctgtccgtgatccacagagacgtgaagccgtccaatgtcctcatcaacaag
gagggtcacgtgaagatgtgcgactttggcattagtggctatttggtggattctgtggcc
aaaacgctggacgctggctgcaaaccctacatggctcccgagaggatcaacccagagctg
aaccagaagggttacaatgtcaagtctgatgtctggagcctcggcatcaccatgatcgag
atggccatcctccgctttccgtacgaatcctgggggactccgttccagcagctgaagcag
gtggtggaagagccatctccccagctcccagctgaccgtttctcccctgagtttgtggac
ttcactgcgcagtgcttgaggaagaaccccgcagagcgcatgagctacttggagctgatg
gagcacccattcttcacgttgcacaaaacaaagaagacggacattgcggcctttgtgaag
gagatcctgggggaggactcctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (43)   

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