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KEGG   Zalophus californianus (California sea lion): 113911474
Entry
113911474         CDS       T07874                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca00230  Purine metabolism
zca01100  Metabolic pathways
zca01522  Endocrine resistance
zca04015  Rap1 signaling pathway
zca04020  Calcium signaling pathway
zca04022  cGMP-PKG signaling pathway
zca04024  cAMP signaling pathway
zca04062  Chemokine signaling pathway
zca04072  Phospholipase D signaling pathway
zca04081  Hormone signaling
zca04114  Oocyte meiosis
zca04211  Longevity regulating pathway
zca04213  Longevity regulating pathway - multiple species
zca04261  Adrenergic signaling in cardiomyocytes
zca04270  Vascular smooth muscle contraction
zca04371  Apelin signaling pathway
zca04540  Gap junction
zca04611  Platelet activation
zca04713  Circadian entrainment
zca04714  Thermogenesis
zca04720  Long-term potentiation
zca04723  Retrograde endocannabinoid signaling
zca04724  Glutamatergic synapse
zca04725  Cholinergic synapse
zca04727  GABAergic synapse
zca04750  Inflammatory mediator regulation of TRP channels
zca04911  Insulin secretion
zca04912  GnRH signaling pathway
zca04913  Ovarian steroidogenesis
zca04914  Progesterone-mediated oocyte maturation
zca04915  Estrogen signaling pathway
zca04916  Melanogenesis
zca04918  Thyroid hormone synthesis
zca04921  Oxytocin signaling pathway
zca04923  Regulation of lipolysis in adipocytes
zca04925  Aldosterone synthesis and secretion
zca04926  Relaxin signaling pathway
zca04927  Cortisol synthesis and secretion
zca04928  Parathyroid hormone synthesis, secretion and action
zca04934  Cushing syndrome
zca04935  Growth hormone synthesis, secretion and action
zca04970  Salivary secretion
zca04971  Gastric acid secretion
zca04972  Pancreatic secretion
zca04976  Bile secretion
zca05032  Morphine addiction
zca05142  Chagas disease
zca05146  Amoebiasis
zca05163  Human cytomegalovirus infection
zca05166  Human T-cell leukemia virus 1 infection
zca05200  Pathways in cancer
zca05207  Chemical carcinogenesis - receptor activation
zca05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:zca00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    113911474 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    113911474 (ADCY1)
   04072 Phospholipase D signaling pathway
    113911474 (ADCY1)
   04024 cAMP signaling pathway
    113911474 (ADCY1)
   04022 cGMP-PKG signaling pathway
    113911474 (ADCY1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    113911474 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113911474 (ADCY1)
   04062 Chemokine signaling pathway
    113911474 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    113911474 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    113911474 (ADCY1)
   04913 Ovarian steroidogenesis
    113911474 (ADCY1)
   04915 Estrogen signaling pathway
    113911474 (ADCY1)
   04921 Oxytocin signaling pathway
    113911474 (ADCY1)
   04926 Relaxin signaling pathway
    113911474 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    113911474 (ADCY1)
   04918 Thyroid hormone synthesis
    113911474 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    113911474 (ADCY1)
   04925 Aldosterone synthesis and secretion
    113911474 (ADCY1)
   04927 Cortisol synthesis and secretion
    113911474 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    113911474 (ADCY1)
   04971 Gastric acid secretion
    113911474 (ADCY1)
   04972 Pancreatic secretion
    113911474 (ADCY1)
   04976 Bile secretion
    113911474 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    113911474 (ADCY1)
   04727 GABAergic synapse
    113911474 (ADCY1)
   04725 Cholinergic synapse
    113911474 (ADCY1)
   04720 Long-term potentiation
    113911474 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    113911474 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113911474 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    113911474 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    113911474 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    113911474 (ADCY1)
   04714 Thermogenesis
    113911474 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113911474 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    113911474 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113911474 (ADCY1)
   05163 Human cytomegalovirus infection
    113911474 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    113911474 (ADCY1)
   05142 Chagas disease
    113911474 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    113911474 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    113911474 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    113911474 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    113911474 (ADCY1)
Enzymes [BR:zca01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     113911474 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom DUF7246 DUF6688
Other DBs
NCBI-GeneID: 113911474
NCBI-ProteinID: XP_027429945
UniProt: A0A6J2BD60
Position
12:968743..1080460
AA seq 1138 aa
MAGAPRGRGGGGGGGGGGGGAGEPGGAERAARPGGRRGLRACNEEFACPELEALFRGYTL
RLEQAATLKALAVLSGLAGALALAELLGAPGPAAGLARGSHPAHCVLFLALLVVTNVRSL
QVPQLQQVGQLALLFSLTFALLCCPFALGRPAGTHAGAASGPAAADQGVWQLLLVTFVSY
ALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRVL
AERCQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKI
YIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCY
YCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKW
QYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETF
FIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDD
KRRALRTASEKLRNRSSFSANVVYTTPGTRVNRYISRLLEARQMELEMADLDFFTLKYKQ
AERERKYHQLQDEYFTSAVVLALVLAALFGLVYLLIIPQNMVVLLLLVFCICFLVACVLY
LHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVSCLPWAWSSSPNGSLVVLRPGG
PNAVLPTAPCESAPHALLCGLVGALPLAVFLRVSSLPKMILLFVLTASYILVLELSGYTR
ASGGGAVSGRSFEPVVAILLFSCTLALHARQVDIKLRLDYLWAAQAEEERDDMERVKLDN
KRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVEC
LRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKCISSHLSTLAD
FAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTG
VQGRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARSLNAERK
MCAYGRAGLQTRLGTGPPPVAPMAGLPVRAGLGALQGSGLPPGPSGQHLRPGAAGKEA
NT seq 3417 nt   +upstreamnt  +downstreamnt
atggcgggggcgccgcgcggccgaggcggaggcggcggcggcggcggaggcggaggcggc
gcgggcgagcccgggggcgccgagcgggcggcccggccgggcggccggcgcgggctgcgg
gcgtgcaacgaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctg
cggctggagcaggcggccacgctgaaggcgctggccgtgctcagcgggctggcgggcgcg
ctggcgctggccgagctgctgggcgcgccggggcccgcggccggcctggccaggggctcg
cacccggcgcactgcgtgctctttctggcgctgctcgtggtcaccaacgtgcgctcgctg
caggtgccccagctgcagcaggtcggccagctggcgctgctcttcagcctcaccttcgcg
ctgctctgctgccccttcgcgctcggccgccccgcggggacccacgccggcgcggcttcg
gggccggcggccgccgaccagggcgtttggcagctccttttggtcaccttcgtgtcctat
gccctgctgcccgtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcg
cacttgctggtcacggccaccttggtgcccgccaagcgcccgcgtctctggaggacactt
ggtgccaatgccctgctcttcctcagtgtgaacatgtacggggtgtttgtgagggtcctg
gccgaacgctgccaaaggaaagccttcctgcaggcccggaactgcatcgaagaccggctg
aggctggaggacgagaatgagaagcaggagcggctgcttatgagccttctgccccggaat
gttgccatggagatgaaggaggacttcctgaagccccccgagaggattttccacaagatt
tacatccagcggcatgacaatgtgagcatcctcttcgcggacatcgtgggcttcacgggc
ttggcgtcacagtgcaccgcgcaggagctggtgaagctcctcaacgagctcttcggcaag
tttgatgaactggccacggagaatcattgtcgccggatcaagatcctcggggactgttat
tactgcgtgtctggcctcacgcagcccaagactgaccacgcccactgctgcgtggagatg
ggcctggacatgattgacaccattacgtcagtggcggaggccacagaggtggatctgaac
atgcgtgtggggctgcacaccggccgggtcctctgcggggtcctcggcctgcgcaagtgg
cagtatgacgtgtggtccaacgacgtgaccctcgccaacgtcatggaggccgccggcctg
cccgggaaggtccacatcacgaagacgaccctggcgtgcttgaacggtgactacgaggtg
gagccggggcacgggcacgagaggaacagttttctgaaaactcacaacattgagaccttc
ttcatcgtgccgtcacatcggcgcaagatatttccagggctgatcctctctgacataaag
cctgccaagaggatgaagttcaaaaccgtgtgctacctgctggtgcagctcatgcactgt
cggaagatgttcaaggcggagatccccttctccaacgtcatgacctgtgaagatgatgac
aagcggagggcgttgagaaccgcgtctgaaaaactcagaaaccgctcgtccttctctgcg
aatgtcgtctacaccaccccaggcacgcgcgtcaacaggtacatcagccgcctcctagaa
gcccgccagatggagctggagatggcggacctggacttcttcaccctgaagtacaagcag
gctgagcgcgagcgcaagtaccaccagctgcaggacgagtatttcaccagtgccgtcgtg
ctcgcgctcgtcctggccgccttgttcggcctcgtctaccttctcatcatcccgcagaac
atggtcgtcctcctgctgctggtgttctgcatctgcttcctggtggcctgtgtcctgtac
ctgcacatcacccgggtccagtgttttccaggatgcctgacgatccagatccgcaccgtc
ttgtgtattttcatagtggtcctaatctactctgtggcccaaggatgtgtggtgagctgc
ctgccctgggcctggagctccagccccaatgggtccctggtggtcctgaggcctggcggc
ccgaacgcggtgctgcccaccgccccctgcgagtcggcgccccatgccctgctctgtggc
ctcgtgggcgccctccctctggccgtcttcctgcgggtgtcctccctacccaaaatgatt
ctgctcttcgtgctcacagcgtcctacatcctggtcctggagctcagcgggtacaccagg
gcctcggggggcggcgcggtctccgggcgcagcttcgagccggtcgtggccatcctgcta
ttctcgtgcacgctggccctgcacgcccggcaggtggacatcaagctgcggctggactac
ctctgggcggcacaggcagaggaggagagggacgacatggagagggtgaagctggacaac
aagaggattctcttcaacctcctgccggcccacgttgctcagcacttcctcatgtccaac
ccccggaacatggacctgtactaccagtcctactcgcaggtgggtgtcatgttcgcctcc
atccccaactttgacgacttctacatcgagctggatggcaacaacatgggggtggagtgt
ttgcgcctcctgaacgagatcatcgctgactttgacgagctcatggacaaagacttttac
aaggacctggagaagatcaagaccatcgggagcacctacatggctgcggtggggctagcg
cccacaaccgggaccaaggcaaagaagtgcatctcctcacacctcagcacgctggctgac
ttcgccatcgagatgttcgacgtcttggatgaaatcaactaccagtcttacaacgacttt
gtgctccgcgtcggcatcaatgttggccccgtggtggctggggtgatcggggctcgaagg
ccgcagtacgacatttggggaaacacggtcaatgtggccagtcggatggacagcaccggc
gtccagggcagaatccaggtgaccgaggaggttcaccggctgctgcgaaggggcacctac
cgctttgtgtgccgcgggaaggtcagcgtcaagggcaagggcgagatgctgacgtacttc
ctggaaggccggaccgatggaaatggctcccaggccaggtccctgaatgcagagcggaaa
atgtgcgcttacgggcgagccggcctccagaccagactgggcacaggcccgcccccggtg
gcccccatggctggcctcccggtcagagccgggctgggggctctgcagggctcggggctc
cccccgggcccctctggccagcacctgcgccccggagcagctgggaaggaggcttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (53)   
   KEGG PATHWAY (53)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (75)   

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