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KEGG   Xiphophorus maculatus (southern platyfish): 102220131
Entry
102220131         CDS       T02923                                 
Symbol
plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
xma  Xiphophorus maculatus (southern platyfish)
Pathway
xma00562  Inositol phosphate metabolism
xma01100  Metabolic pathways
xma04012  ErbB signaling pathway
xma04020  Calcium signaling pathway
xma04070  Phosphatidylinositol signaling system
xma04370  VEGF signaling pathway
xma04625  C-type lectin receptor signaling pathway
Module
xma_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:xma00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102220131 (plcg2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102220131 (plcg2)
   04370 VEGF signaling pathway
    102220131 (plcg2)
   04020 Calcium signaling pathway
    102220131 (plcg2)
   04070 Phosphatidylinositol signaling system
    102220131 (plcg2)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102220131 (plcg2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:xma04131]
    102220131 (plcg2)
Enzymes [BR:xma01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     102220131 (plcg2)
Membrane trafficking [BR:xma04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102220131 (plcg2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    102220131 (plcg2)
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 SH3_1 SH3_9 PH EF-hand_PLCG1 SH2_1 SH3_2 PH_12 PH_14 Saf4_Yju2
Other DBs
NCBI-GeneID: 102220131
NCBI-ProteinID: XP_023202860
Ensembl: ENSXMAG00000011966
UniProt: M4AC30
Position
2:266105..299959
AA seq 1247 aa
MARSGPQGEMTEYRKIVIKRDLEMGVVMTVFRQKAERLTVQVIMETRQVAWTRTADKTDG
VLDLSEIREVRPGRNSKDFERFKDGKDKHNDNTCFTIFYGSQFVLNTLSLGADSVDEAQK
WLTGLELLREETLAAPTPVLIESWLRKQMYSVNQTKKNSLSVKELKALLPLLNYKVPCSR
TLKDKLQEVGVKKDRLDFEQFHKFYNLMMFEQNEILDEFKREACSFILGNTDKPDASAVL
LHDFQRFLIYDQKEPWANDLNQVRELMTIFIDDTMRKTNDPEFTVSEFLSFLFSKENSIW
DEKFSEINNLDMNNPLSHYWISSSHNTYLTGDQLLSESSTEAYVRCLRWGCRCVELDCWE
GPGEPIIYHGWTRTTKIKFEDVVKAINDHAFVASDFPLILSIEEHCPIEQQRQMARIFKD
VFGDKLLAEPVEQLAEQLPSPTQLRGKIILKHKKVNMEGGATAKDFRKGQKQGDLDIWDP
VDQRWNRHYCVISDDKLYYAEECEEEDEDPRKYQDLHCSEPWFHGRIQEGRLMAERLIHD
YCAETGGQDGTFLVRQSDRYVTDFTLSFWRTGRVQHCRIRSSTDGGYAYFFLTPNLHFPS
VYSLIEHYRENPLRCQDFELRLTEAVPKPDPHLQERWFYSNLSRGQAEDYLLRIPRDGAF
LIRQREGEPDSFAITFRGDGKVKHCRIQKEGSVYLLGTTTEFESLVELVNYFKKKPLYRK
IKLRYPVTPELVERFSANENCSSIYMETYVKPNEIEPSLPQNTVRALYSYQAKRPDELSF
TKGAMIHNVSKEVDGWWKGDYGGRLQLFFPANYVEEVSNSAQTDAKAQEMEDNPLGELCK
GIVEISMYNIQNMKNGKYRKPHVLTLQHKEQDSVQFDLAAGSLEELFEWYQVAWDVTQRE
MSKQYHREQEIKQQEEVEKKAEVAMEMSDLVVYCQPRSKEKDRFDNYNYKEVRSFMENKI
PGKSRTKEFLCYNRKALSRIYPKNQRVESSNFDPYPLWEVGCHMVALNYQTADKYTQLNS
ALFSLNGNSGYVLQPEMMRSDGYDPHQEKKKVKYSIRVKVIAARHLPKLGRSIASPFVEV
ELCGHSEEKFKTIVYRDNGLNPVWKAPAEPVEFSVFEPELSFLRFVVNEEDMFSDPNFLA
QATLPVKGIRSGYRSVPLKNGYNEKLDLAALLVYINVQQAGRAEEELYSSSSQLRKKQAE
HSEPFLYDTHSNLQRAALPHPHGQLVRESSERHRSKEKKINNSKFYT
NT seq 3744 nt   +upstreamnt  +downstreamnt
atggcccgttccggcccgcagggcgagatgacggagtacaggaagatcgtgatcaagcgg
gacctggagatgggcgtggtcatgacggtgttccggcagaaggcggagcggctcaccgtg
caggtcatcatggagacccggcaggtggcctggacgcgcaccgcggataaaaccgacgga
gtcctggacctgtctgagatcagggaagtccgtccaggaagaaactccaaagactttgag
cgcttcaaagacgggaaggacaaacacaatgacaacacctgcttcaccatcttctacggc
tcccagttcgtcctcaacaccctcagcctgggagcggattcggtggacgaggctcagaaa
tggctgactgggctggagctgttgagagaagagacgctggcggcaccgaccccggttctg
atcgagagctggctcaggaagcagatgtattctgtcaaccagaccaagaaaaacagcctc
tctgtgaaggagctgaaggcgttgctgccgctgctgaactacaaggttccctgctctcgc
actctgaaggacaagctgcaggaagtgggagtgaagaaggaccgcctcgactttgagcag
tttcataagttttataacctgatgatgttcgagcagaacgagatcctggacgagttcaaa
cgggaagcctgttccttcatcctggggaacacggacaaaccggacgcttcagccgtgctg
ctgcatgatttccaacgattcctcatttatgaccagaaggagccgtgggccaacgatctg
aaccaggtcagagagctgatgaccattttcatcgatgacaccatgagaaaaactaacgac
cctgagtttaccgtcagcgagttcctgagtttcctgttttccaaggaaaactcaatttgg
gatgaaaagttctctgaaatcaacaacctggacatgaacaacccgctgtcccactactgg
atcagctcctcacacaacacgtacctgacaggtgaccagctcctcagcgagtcgtccacc
gaggcgtacgtccgctgcctccgctggggttgccgctgcgtcgaattggactgctgggaa
ggtccaggagaaccgatcatctaccacggctggaccagaaccactaagatcaagttcgaa
gacgtggtgaaagccataaacgaccacgccttcgtcgcctcagacttcccgctcatcctg
tccattgaggagcactgccccatcgagcagcagcgccagatggcgcgcatcttcaaggac
gtcttcggagataagctgctggccgagccggtggagcagttggccgagcagctgccctcg
cccacacagctgaggggcaagatcatcctgaagcacaaaaaggtgaacatggagggcgga
gccacagccaaggacttcaggaaggggcagaagcagggagacctggacatctgggacccg
gtggaccagcgctggaaccgccactactgtgtgatctctgacgacaagctgtactacgca
gaggagtgtgaggaggaagatgaagatccccggaagtaccaggacctgcactgttcggag
ccctggtttcacggccgcatccaggagggccggctgatggcggagcgcctgatccatgac
tactgcgcagaaaccgggggacaggacgggaccttcctggtccgacagagcgacagatac
gtcaccgacttcaccctctccttctggcgcaccggcagagtgcagcactgccggatccgc
tccagcacagacggaggctacgcctacttcttcctgacccccaacctgcacttccccagc
gtctactctctgatcgagcactaccgggaaaacccgctgcgctgccaggacttcgagctg
cgcctcaccgaagccgtgcccaagccagaccctcacctgcaggagcgatggttctacagc
aacctgagcagaggccaagcggaggattacctgctcaggatccccagagacggagcgttc
ctgatccgacagagggaaggagaaccagactccttcgccatcaccttcagaggcgatggg
aaggtgaagcactgccggatccagaaggagggcagcgtctacctgctggggaccaccacg
gagttcgagtctctggtggagctggtgaactacttcaagaagaagccgctgtatcgcaag
atcaagctgcgttacccagtgacaccggagctggtggagcgcttcagcgcaaacgagaac
tgctcttccatatacatggagacatacgtgaagcccaatgagatcgagccgtcgctgccc
cagaatactgtccgggctttgtacagctaccaggccaagcgacccgacgagctgagcttc
actaaaggagcgatgattcataacgtgtccaaggaagtggacggatggtggaaaggcgac
tacggagggcgactgcagctcttcttccctgccaattacgtggaggaagtgtccaattca
gcacagactgacgccaaggctcaggagatggaagacaaccctctgggggaactctgtaag
ggaattgtggagatctccatgtacaacatccagaacatgaagaacggtaaatacaggaag
ccgcatgtcctgacgctgcagcacaaggagcaggacagtgtgcagttcgacctggctgcc
gggtcgctggaggagctgttcgagtggtaccaggtggcctgggacgtgacccagagggag
atgagcaagcagtaccaccgggagcaggagataaaacaacaggaggaagtggagaagaag
gcagaggttgccatggagatgtctgatctggtggtctactgccagcctcgcagcaaggag
aaagaccgcttcgacaactacaactataaagaggttcgctccttcatggagaacaagatt
ccagggaagagccgcaccaaggaattcctttgctataaccgcaaagctctgagtcggatc
taccccaaaaaccagcgggtggagtcctccaactttgacccctacccactatgggaggtg
ggctgccatatggtggcgctcaactaccagaccgcagataaatacactcagctgaacagc
gccctcttcagcctgaacgggaacagcggctacgtgctgcagcctgagatgatgcgttcc
gacggctacgacccgcatcaggagaagaaaaaagtcaagtacagcatcagagtcaaggtg
attgctgccagacacctgcccaagctgggccgcagcatcgccagcccattcgtggaggtg
gaactgtgcggacactcagaggagaaattcaagaccatcgtataccgtgacaacggcctg
aacccggtgtggaaagcgccggcagagccggtggagttcagcgtgttcgagccggagctc
agctttctgcgcttcgtggtcaatgaggaggacatgttctccgaccccaacttcctggcc
caggccacacttcctgtcaaaggcatccgctcaggctatcgctccgtcccgctgaagaac
ggctacaatgagaaactggatctggccgctctgctcgtctacatcaacgttcagcaggcg
gggagagccgaggaggagctgtactcgtcgtccagccagctgaggaagaagcaggcggag
cacagcgagcccttcctgtacgacacacacagcaacctgcagcgcgccgcgctgccgcac
ccgcacggccagctggtccgcgagtccagcgaaagacacaggtcaaaggagaagaagata
aacaacagcaagttttacacctga

  All links  
Gene (32)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (14)   
   Pfam (14)   
All databases (49)   

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