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KEGG   Vicugna pacos (alpaca): 102530139
Entry
102530139         CDS       T08098                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X2
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
vpc  Vicugna pacos (alpaca)
Pathway
vpc04010  MAPK signaling pathway
vpc04015  Rap1 signaling pathway
vpc04218  Cellular senescence
vpc04620  Toll-like receptor signaling pathway
vpc04664  Fc epsilon RI signaling pathway
vpc04668  TNF signaling pathway
vpc04714  Thermogenesis
vpc04750  Inflammatory mediator regulation of TRP channels
vpc04912  GnRH signaling pathway
vpc04935  Growth hormone synthesis, secretion and action
vpc04936  Alcoholic liver disease
vpc05014  Amyotrophic lateral sclerosis
vpc05022  Pathways of neurodegeneration - multiple diseases
vpc05132  Salmonella infection
vpc05135  Yersinia infection
vpc05145  Toxoplasmosis
vpc05161  Hepatitis B
vpc05169  Epstein-Barr virus infection
vpc05170  Human immunodeficiency virus 1 infection
vpc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
vpc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vpc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102530139 (MAP2K3)
   04668 TNF signaling pathway
    102530139 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102530139 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    102530139 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    102530139 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102530139 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    102530139 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102530139 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102530139 (MAP2K3)
   05161 Hepatitis B
    102530139 (MAP2K3)
   05169 Epstein-Barr virus infection
    102530139 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102530139 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102530139 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102530139 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    102530139 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102530139 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102530139 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vpc01001]
    102530139 (MAP2K3)
Enzymes [BR:vpc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102530139 (MAP2K3)
Protein kinases [BR:vpc01001]
 Serine/threonine kinases: STE group
  STE7 family
   102530139 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 102530139
NCBI-ProteinID: XP_006213871
UniProt: A0A6I9IJP2
Position
Unknown
AA seq 347 aa
MEPPAASPPAGVPPSKGKSRRKKDLRITCVSKPPAPSPTPPRNLDSRTFITIGDRNFEVE
ADDLVPISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKKMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTSHQTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagccgcccgccgcgagcccgcccgccggcgtgcccccgtccaaaggaaaatcccgg
aggaagaaggatctacgaatcacctgtgtgtccaagccaccggcgcccagccccacgccc
ccccggaacctggactcccggaccttcatcaccattggagacaggaacttcgaggtggaa
gctgacgacctggtgcccatctcggagctgggccggggggcctatggggtggtggagaag
gtgcggcatgcccagagcggcaccatcatggccgtgaagcggatccgggccaccgtgaac
tcgcaggagcagaagcgcctcctcatggacctggacgtcaacatgcggacggttgactgc
ttctacactgtcaccttctatggggccctcttcagagagggagacgtgtggatctgcatg
gagctcatggacacttccctggacaagttttaccggaaggtgcttgataaaaaaatgacg
attccagaggacattctgggggaaattgctgtgtctatcgtgagggccctggagcacctg
cacagcaagctgtccgtgatccacagagatgtgaagccgtccaacgttctcatcaacaag
gaaggccatgtgaagatgtgtgacttcgggatcagtggctacttggtggactctgtggcc
aagacaatggacgctggctgcaagccctacatggctccagagaggatcaacccagagctg
aaccagaagggctacaacgtcaagtctgacgtgtggagtcttggcatcaccatgattgag
atggccattctgcggtttccttatgagtcctgggggaccccgttccagcagctgaagcag
gtggtggaggagccatccccccagctcccagctgaccgtttctccccagagtttgtggac
ttcaccgcacagtgcctgagaaagaaccccgcggagcgcatgagctacctggagctgatg
gaacaccctttcttcacctcgcaccaaaccaagaagaccgacattgctgcctttgtgaag
gagatcctgggagaggattcgtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (11)   
   Pfam (11)   
All databases (45)   

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