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KEGG   Varanus komodoensis (Komodo dragon): 123025316
Entry
123025316         CDS       T07701                                 
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
vko  Varanus komodoensis (Komodo dragon)
Pathway
vko00562  Inositol phosphate metabolism
vko01100  Metabolic pathways
vko04012  ErbB signaling pathway
vko04020  Calcium signaling pathway
vko04070  Phosphatidylinositol signaling system
vko04370  VEGF signaling pathway
vko04625  C-type lectin receptor signaling pathway
Module
vko_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:vko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    123025316 (PLCG2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    123025316 (PLCG2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vko04131]
    123025316 (PLCG2)
Enzymes [BR:vko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     123025316 (PLCG2)
Membrane trafficking [BR:vko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    123025316 (PLCG2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    123025316 (PLCG2)
SSDB
Motif
Pfam: PI-PLC-X SH2 EF-hand_PLCG2 PI-PLC-Y SH3_1 SH3_9 C2 PH PH_12 SH2_1 EF-hand_PLCG1 SH3_2 PH_14 UCH_N EF-hand_like GDPD zf-HC5HC2H_2
Other DBs
NCBI-GeneID: 123025316
NCBI-ProteinID: XP_044289838
Ensembl: ENSVKKG00000000228
Position
Unknown
AA seq 1249 aa
MSRKSMDYGDLPEYEKSQIKRTLELGTVMTVYNLKKSNPERRTIQVIMETRQVAWSKTAD
RIEGFLDLMEIKEIRLGKNSKDFERGKAARQKDEHCFTIFYGTQFVLNTLSLAADTKDDA
DKWLCGLNILRQEAMNAATPAITESWLRKLIYSVDQSRRNSISLRELKTVLPSVNFKVSS
VKFLKDKFAEINAVKEELSFEQFHLFYKKIMFEQQKLILDEFKKDSTVFFLGNTDRPDAS
AVHLHDFQRFLIHEQQESWAQDLNKVREWMSKFIDDTMRETDEPFLYVDEFLTYLFSKEN
SIWDDKYDSVDPQDMNNPLSHYWISSSHNTYLTGDQLRSESSAEAYIRCLRMGCRCIELD
CWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKEHAFVTSEYPVILSIEEHCSVEQQRYIAK
VFREVFGDQLLMKPIEASADQLPSPTQLKEKFIIKHKKLGPKGDVDVNTEEKKEEKKQQG
ELYMWDTIDQRWTRHYCAVANEKLSFSDDIEQNADEESSKEMQRTELHCGEKWFHGKMKE
GRNTAERLLQEYCAEMGGKDGTFLVRESEAFPKDYTLSFWRSGRVQHCRIRSSTDGDTVK
YYLTDNLTFDSICDLVQHYKEAHLRCAEFELRLTDPVPNPKPHESEKWYYSNLSRGEAED
MLMRIPRDGAFLIRKREEPDSYAMTFRAEGKVKHCRIKQEGRLFVLGTSAYFESLVELVN
YYEKHPLYRKMKLRYPVTEELLDRYSMEKDPSSLYDVKMYVEPTEITPSVPQRTVKALYD
YQAKREDELTFCRGALIHNVSKETGGWWKGDYGCKVQYYFPSNYVEDMSTDSMEELEKQI
IEDNPLGSLCRGILDLNMYNVAKMSQGKYGKDFVFVLEPKNNTDLPIEFATDKVEELFEW
YQNIREITWRTAEEANIRTYWEKKQLIAMELSDLVIYCIPTSKTKDNLENPNFKEIRSFV
ETKAESIVKQKPTDLLKYNQKGLTRIYPKGQRVDSSNYDPFRFWFCGSQMVALNFQTPGK
NFFMEVLSLPHSFPHLNQCSAAAWLNLSSCLFVWDCSVGLLDLTCADLGLTSVDYSMFIV
VTLKLQIHFVTDDNGLNPVWASQEQVKFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATFP
IKGIKSGFRAVPLKNGHSEDLELASLLVYCEMQQIQESEEELYSSFRQLRQRQAELNNQL
YDSRRNIRSPNRDALLQEFSVNEGQLRVYQETCNKRLREKRVSNSKFYS
NT seq 3750 nt   +upstreamnt  +downstreamnt
atgtctcggaaaagtatggactatggggaccttccagaatacgaaaagagccagatcaaa
aggaccctggagttgggcactgtcatgacagtctataacctcaaaaagagtaatccagag
aggagaacaattcaggtcatcatggaaacaaggcaggtagcgtggagtaagacagctgac
aggattgaaggattcctggatttgatggaaataaaggaaatccgtctagggaaaaattca
aaggattttgagcgtgggaaagcagcacgacaaaaggatgagcactgtttcactattttc
tatggtactcagtttgttctcaacaccttaagtttagcagctgacacaaaggatgatgct
gacaaatggctgtgtggtttaaatattttgcgtcaagaagctatgaatgctgccactcca
gcaattacagagagctggctgagaaagctgatttactctgtggatcagtccagaaggaac
agcatcagccttagagaactaaagacggtgcttccatcagtgaactttaaagtgagcagt
gtaaagttcctgaaagataagtttgcagaaataaacgctgttaaagaagagcttagcttt
gagcaatttcatctgttctacaagaaaattatgtttgagcaacagaaattgattctcgat
gaattcaagaaggattccactgtgttttttttaggaaacacagaccgtccagatgcttca
gcggtgcatttgcatgactttcagagatttttgatacatgaacaacaggaatcttgggca
caggatcttaataaagtaagagaatggatgtctaaatttattgatgacactatgagagaa
actgatgaaccatttctctatgttgatgagttccttacttaccttttttcaaaagaaaac
agtatctgggatgacaaatatgattcagttgaccctcaggacatgaataaccctttgtcc
cattactggatttcttcttcacataatacatacctcacaggagaccagcttcgtagtgaa
tcttctgcagaagcttatattagatgccttcgaatgggatgccgttgcattgagttggat
tgctgggatggtcctgatgggaagcccatcatttatcatggatggacacggacaacaaaa
attaaatttgatgatgttgtgcaggcaatcaaggaacatgcgtttgttacatctgagtac
cccgtgattttgtcaattgaggagcactgcagtgtggagcagcagcgatatattgccaaa
gtgttcagagaggtctttggggatcagcttctaatgaagcccatcgaagctagtgctgat
cagctgccatcaccaactcagctgaaagaaaagttcatcatcaagcataaaaagttgggc
cccaaaggtgatgtagatgtgaacacagaagaaaagaaagaggagaaaaagcaacaagga
gaactctacatgtgggacaccatagatcagagatggactcgtcattactgtgctgtagcc
aatgaaaaactttcattcagtgatgatatagagcagaatgctgatgaagagtcatccaag
gaaatgcaacgcacagagctgcactgtggtgagaaatggttccatggaaaaatgaaagaa
gggagaaacaccgctgagaggttgctccaggagtattgcgctgaaatgggtggcaaggat
ggaacattcctagtgagagagagtgaagctttccctaaggactacacactttcattctgg
agatctggtagagtccagcactgccgtatccgttcttcaacggatggagatactgtaaag
tattacttgacagacaacctcacctttgatagcatctgcgatctagtccagcattataaa
gaagcacacttgcgctgtgcagagtttgaactgcggttgactgatcctgtgcctaacccc
aagcctcatgaatcagagaagtggtactacagtaacctgagccgaggagaagcagaagat
atgctgatgcgaattcccagggatggagcctttttgataagaaagagagaggaacctgat
tcctatgccatgacttttagagctgaagggaaagtaaagcactgccgcatcaagcaagaa
ggccgcctctttgtcttgggcacatcagcctattttgagagtttagtggaactggtgaac
tactatgagaaacatccgttgtacaggaaaatgaagttgcgctaccccgtgaccgaggag
ctgctggaccgctacagcatggagaaagaccctagttcattatatgatgtaaagatgtat
gtggagccgactgaaataacaccgtctgtgccccagagaacggttaaagccttgtatgac
taccaagctaaaagagaagatgagctgactttttgccgtggggccttaattcataatgtc
tcaaaggaaactggtggctggtggaaaggagattatggatgcaaagttcagtactatttt
ccatctaattatgttgaagatatgtcaactgatagcatggaagagcttgagaaacagata
attgaagataaccctttaggatcattatgccggggtattttggacctcaatatgtataat
gttgcaaaaatgtcacagggaaaatatgggaaagattttgtcttcgtcctggaacccaag
aataatactgatctgcccattgaattcgccacagacaaagtggaagagctgtttgagtgg
tatcaaaacatcagggagatcacatggagaactgctgaagaggcaaatatcagaacatac
tgggaaaagaagcagttaatagccatggaattatctgatttggtaatctactgcataccc
acaagcaaaaccaaggataatctagaaaatcccaatttcaaagaaatccgttcctttgtg
gagaccaaggcggaaagcatagtcaagcagaagcccactgatctactaaaatacaatcag
aagggactgacgcggatatatccaaaagggcaaagggtggactcctcgaattatgatccc
ttccgcttttggttttgtggctcgcagatggtggctcttaatttccagacaccaggtaag
aatttctttatggaagtgctgagccttccccattctttccctcatttaaatcagtgctca
gctgcagcttggttgaacctttccagctgtttgtttgtttgggactgctctgttggcctc
cttgatctcacctgtgcagaccttggtttgacatcagtggattacagcatgtttatagta
gttacacttaaattacaaattcattttgttacagatgataatggccttaacccagtttgg
gcatctcaagagcaagtgaagtttgaaatttatgatccaaacctagcatttctgcgcttt
gttgtctatgaggaggacatgtttagtgatcctaatttcttagcacatgccacatttcct
atcaaaggaatcaaatcaggctttcgggcagtccctctcaaaaacggacatagcgaggat
ttagagctggcttccctcttggtttattgtgagatgcagcaaattcaggaaagtgaagaa
gagctctattcatcatttcggcagctacggcagcgccaagcagaactgaacaatcagtta
tatgactcccgacggaacataaggagccccaaccgagatgcattattgcaagaattcagc
gtgaatgagggtcagttacgagtatatcaagagacttgcaacaagagattgagagagaaa
agagtcagcaacagcaaattctactcctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (17)   
   Pfam (17)   
All databases (47)   

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