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KEGG   Vulpes vulpes (red fox): 112910069
Entry
112910069         CDS       T05911                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp04010  MAPK signaling pathway
vvp04020  Calcium signaling pathway
vvp04022  cGMP-PKG signaling pathway
vvp04024  cAMP signaling pathway
vvp04218  Cellular senescence
vvp04260  Cardiac muscle contraction
vvp04261  Adrenergic signaling in cardiomyocytes
vvp04270  Vascular smooth muscle contraction
vvp04530  Tight junction
vvp04713  Circadian entrainment
vvp04723  Retrograde endocannabinoid signaling
vvp04724  Glutamatergic synapse
vvp04725  Cholinergic synapse
vvp04726  Serotonergic synapse
vvp04727  GABAergic synapse
vvp04728  Dopaminergic synapse
vvp04911  Insulin secretion
vvp04912  GnRH signaling pathway
vvp04921  Oxytocin signaling pathway
vvp04924  Renin secretion
vvp04925  Aldosterone synthesis and secretion
vvp04927  Cortisol synthesis and secretion
vvp04929  GnRH secretion
vvp04930  Type II diabetes mellitus
vvp04934  Cushing syndrome
vvp04935  Growth hormone synthesis, secretion and action
vvp04973  Carbohydrate digestion and absorption
vvp05010  Alzheimer disease
vvp05020  Prion disease
vvp05022  Pathways of neurodegeneration - multiple diseases
vvp05031  Amphetamine addiction
vvp05207  Chemical carcinogenesis - receptor activation
vvp05410  Hypertrophic cardiomyopathy
vvp05412  Arrhythmogenic right ventricular cardiomyopathy
vvp05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    112910069 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    112910069 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    112910069 (CACNA1D)
   04929 GnRH secretion
    112910069 (CACNA1D)
   04921 Oxytocin signaling pathway
    112910069 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    112910069 (CACNA1D)
   04924 Renin secretion
    112910069 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    112910069 (CACNA1D)
   04927 Cortisol synthesis and secretion
    112910069 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    112910069 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    112910069 (CACNA1D)
   04727 GABAergic synapse
    112910069 (CACNA1D)
   04725 Cholinergic synapse
    112910069 (CACNA1D)
   04728 Dopaminergic synapse
    112910069 (CACNA1D)
   04726 Serotonergic synapse
    112910069 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    112910069 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    112910069 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    112910069 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112910069 (CACNA1D)
   05020 Prion disease
    112910069 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    112910069 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    112910069 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    112910069 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    112910069 (CACNA1D)
   05414 Dilated cardiomyopathy
    112910069 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112910069 (CACNA1D)
   04934 Cushing syndrome
    112910069 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:vvp04040]
    112910069 (CACNA1D)
Ion channels [BR:vvp04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   112910069 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 112910069
NCBI-ProteinID: XP_025842104
UniProt: A0A3Q7R7M5
Position
Unknown
AA seq 2209 aa
MMMMMMMKNMHHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIIAEEDPAPCAFSGNGRQCATNGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GGGENPGGCGSLWCWWKRRGTAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMAT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
VYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADHYFTDAWNTF
DALIVVGSVVDIAITEVNPTESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSR
GEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTF
PQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCA
FLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRI
QPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEE
LRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYP
AKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKREEEEDGFKRNGALLGNHVNH
VNSDRRDPLQQTNTTHRPLHVQRPSVPPASDTERPLFPPAGNSGCHSHHNHNSVGKQAPS
STNANLNNANMSKAAPGKRPSIGNLEHMSENGHHSSHKHDREPQRRSSIKRTRYYETYIR
SDSGDEQFPTICREDPEPHGYFRDARCLEEQEYFSGEEGYEDVGSPAGGRQSYNYYNRYP
GSSWDFERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPTSHRRSSFNFECLRRQS
SQEEVPLSPTFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRD
WTPCYAPLIQVERPEALDQVNGSLPSLHRSSWYTDEPGISYRTFTPASLTVPSSFRNKNS
DKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASNLLNGTVH
PRANGGVGPVSHRQDYELQDFGPGYSDEEPDLGRDEEDLADEMICITTL
NT seq 6630 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaacatgcaccaccaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtgggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgccctcttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagttgagacatttttgaagatt
attgcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcaggaggcttcgatgtcaaagccctccgc
gcctttcgggtgttacgaccacttcgactcgtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggtccccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaacc
tgtttttttgcggactcagatatcatagctgaagaggacccagcgccatgtgcgttctca
gggaatggacgccagtgtgccaccaatggcacggagtgtaggagtggctgggttggccca
aatggaggcatcaccaattttgataattttgcctttgccatgctcaccgtgttccagtgc
atcaccatggagggctggacagatgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattctcaaaagaaagagagaaggctaaagcccgggga
gatttccagaagctccgggagaagcagcagctggaggaggatctaaagggctacttggat
tggatcacccaagcagaagacattgatcctgagaacgaggaagaaggaggagaggaaagc
aaacgaaacaccagcatgcccaccagcgagaccgagtcggtgaacacagagaacgtaagt
ggcggaggcgagaatccaggcggctgtgggagtctctggtgctggtggaaaagaagaggc
acggccaaggctgggccctctgggtgtcggcggtggggccaagccatctcaaaatccaaa
ctcagccgacgctggcgtcgctggaaccgcttcaatcgcagaagatgtcgtgctgctgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaataccttaaccatt
tcctctgagcactacaatcagcctgactggttgacgcagattcaagatatcgctaacaaa
gtcctcctggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggtctccag
gcctatttcgtctctctcttcaatcggtttgattgcttcgtggtgtgtggtggcattacc
gagaccatcttggtggagctggaaatcatgtctcctctggggatctctgtgtttcggtgc
gtgcgcctcttaaggattttcaaggtgaccaggcactggacttccctgagcaacttagtg
gcctccttgttaaactccatgaagtccatcgcttcgctgttgcttctgctttttctcttc
atcatcatcttttccttgcttgggatgcagctgtttggtggcaagtttaattttgacgaa
acacagaccaagcggagcacctttgacaattttcctcaagcccttctgaccgtattccag
atcctgacaggggaggactggaacgccgtgatgtatgatggcattatggcctatggcggc
ccctcgtcttcggggatgatcgtctgcatctacttcatcatcctcttcatttgtggtaac
tatatcctactgaatgtcttcttggccatcgctgtagacaatcttgctgatgctgaaagt
ttgaatactgcccagaaagaggaagctgaagagaaggagaggaaaaagattgccagaaaa
gagagcctggaaaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgac
aataaggttacaattgatgactaccgagaagaggatgaagacaaggacccctacccacct
tgtgatgtgccagtaggggaagaggaagaggaggaggaagaggatgaacctgaggttcct
gctggcccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcgcccccatc
cccgaaggaagtgcattcttcattctgagcaagaccaacccgatccgcgtgggctgccac
aagctaatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagtagt
gccgcccttgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatggcgact
tttggagctttcctccacaaaggggctttctgcagaaactacttcaatctgctggatatg
ctggttgttggggtgtcactggtatcatttgggattcaatccagtgccatctccgttgtg
aagattctgagggtcttaagggtcctgcggccactcagggcaataaacagagcaaaagga
cttaagcatgtggtccaatgtgtcttcgtggccatccggaccattggcaacatcatgatt
gtcaccacccttctccagttcatgtttgcctgcatcggagtacagttgttcaagggaaag
ttctatcgctgtacagatgaagccaaaagtaaccccgaagagtgcagagggcttttcatc
ctctacaaggatggggatgttgataaccctgtggtccgggagagaatctggcaaaacagc
gattttaactttgacaacgtcctttctgctatgatggcgctgttcacggtctccacattc
gagggctggcctgcgttactgtataaagccatcgactcaaatggagagaatgtcggcccc
gtctacaattaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtggct
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactacgagcagtccaagatgttcaatgacgccatggacattctg
aacatggtcttcactggggtgttcactgtcgagatggttttgaaagtcatcgcatttaaa
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgaccactatttcactgatgcatggaacactttt
gatgccttaattgttgttggtagcgtcgttgatattgctataactgaagtgaatccaact
gaaagtgaaaatgtccctgtcccaactgccacacccgggaactctgaagagagcaataga
atctccatcacctttttccgtcttttccgagtgatgcggttggtgaaacttctcagcagg
ggggaaggcatccggacgttgctgtggacttttataaagtcctttcaggctctgccctat
gtcgccctcctcatagccatgctgttcttcatctacgcggttatcggcatgcagatgttt
ggaaaggttgctatgagagataacaaccagatcaacaggaacaacaatttccagaccttt
cctcaggcggtgctgctactcttcaggtgtgcgacgggtgaagcctggcaggagatcatg
ctggcctgtctcccggggaagctttgtgaccctgagtcagactataaccctggggaggag
tacacatgtgggagcaactttgccattgtttatttcatcagtttttacatgctctgtgca
tttctgatcatcaacctgtttgtggctgtcatcatggacaactttgattatctgactcgg
gactggtccattctagggcctcaccatttagatgaattcaaaagaatatggtcagaatat
gaccctgaggcaaaaggaaggatcaagcaccttgatgtggtcactctgctccgacgcatc
cagcctcccctggggtttgggaaattatgcccacacagagtagcctgtaagagactagtt
gccatgaacatgcctctcaacagtgatgggacagtcatgtttaatgcaaccctgtttgct
ttggttcgaacggctcttaaaatcaagacagaagggaacctggaacaagctaatgaggaa
ctccgagctgtgataaagaaaatctggaagaaaaccagcatgaaactgcttgaccaagtt
gtccctccagctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgata
caggactactttaggaaattcaagaaacggaaagaacaaggactggtgggaaaataccct
gcgaagaacaccaccattgccctacaggcaggattaaggacactgcatgacattgggcca
gaaatccggcgtgctatatcatgtgatttgcaagatgacgagccggaggaaacaaaacga
gaagaagaagaagatggattcaaaagaaatggtgccctgcttggaaaccatgtcaatcat
gttaatagtgataggagagacccccttcagcagaccaataccacccaccgtcccctgcat
gtccaaaggccttcagttccacctgcaagtgatactgagagaccgctgtttcctccagca
ggaaattcggggtgtcatagccatcataaccataattccgtaggaaagcaagctcccagc
tcaacaaatgccaatctcaataatgccaatatgtccaaagctgcccctggaaagcggccc
agcattgggaaccttgagcatatgtctgaaaatgggcatcactcctcccacaagcatgac
cgggagcctcaaagaaggtccagtattaaaagaacccgctattatgaaacttacattaga
tctgactcgggagatgagcagttcccaaccatctgccgagaggatccggagccccacggc
tacttcagggacgcccgctgcttggaggagcaggagtacttcagcggcgaggagggctat
gaggatgtgggctctccggcggggggcaggcagagctacaactactacaaccgatacccg
ggcagcagctgggacttcgagcggccccgaggctaccatcacccccaaggcttcttggag
gatgacgactcgcccgtttgctatgactcccggagatctccaaggagacgcctactacct
cccaccccgacatcgcaccggagatcctccttcaactttgagtgcctgcgccggcagagc
agccaggaggaggtcccgctgtcccccaccttcccccaccgcacagccctgccactgcac
ctgatgcagcaacagatcatggcagttgcgggcctggattccagtaaagcccagaagtac
tcgccgagccactcaacccggtcgtgggccacccctccagcgacccctccgtaccgagac
tggacgccatgctacgcgcccctgatccaggtggagcggccagaggccctggaccaggtc
aacggcagccttccatccctgcaccgaagctcatggtacacggacgagcccggcatctca
taccgaactttcacaccagccagcctgactgtccccagcagcttccgcaacaaaaacagt
gacaagcagaggagtgcagacagcttggtggaggcagtcctgatatccgaaggcttagga
cggtatgcaagggacccaaaatttgtatcggcaacaaaacacgaaatcgccgatgcctgt
gacctgaccatcgatgagatggagagtgcagccagcaacctgctcaatgggactgtgcat
ccccgggctaacgggggcgtgggccctgtctcacaccggcaggactatgagctccaggac
tttgggccgggctacagcgatgaggagcctgaccttggaagagatgaggaggacctggca
gatgaaatgatatgcatcaccaccctgtag

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