ID   D0P3G4_PHYIT            Unreviewed;      1015 AA.
AC   D0P3G4;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   05-FEB-2025, entry version 64.
DE   RecName: Full=ATP-grasp domain-containing protein {ECO:0000259|PROSITE:PS50975};
GN   ORFNames=PITG_20994 {ECO:0000313|EMBL:EEY59748.1};
OS   Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY59748.1, ECO:0000313|Proteomes:UP000006643};
RN   [1] {ECO:0000313|Proteomes:UP000006643}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX   PubMed=19741609; DOI=10.1038/nature08358;
RG   The Broad Institute Genome Sequencing Platform;
RA   Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA   Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA   Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA   Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA   Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA   Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA   Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA   Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA   Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA   Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA   Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA   Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA   Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA   Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA   Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA   Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA   Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA   Nusbaum C.;
RT   "Genome sequence and analysis of the Irish potato famine pathogen
RT   Phytophthora infestans.";
RL   Nature 461:393-398(2009).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS028368; EEY59748.1; -; Genomic_DNA.
DR   RefSeq; XP_002895162.1; XM_002895116.1.
DR   AlphaFoldDB; D0P3G4; -.
DR   STRING; 403677.D0P3G4; -.
DR   EnsemblProtists; PITG_20994T0; PITG_20994T0; PITG_20994.
DR   GeneID; 9466773; -.
DR   KEGG; pif:PITG_20994; -.
DR   VEuPathDB; FungiDB:PITG_20994; -.
DR   eggNOG; ENOG502QUGS; Eukaryota.
DR   HOGENOM; CLU_310261_0_0_1; -.
DR   InParanoid; D0P3G4; -.
DR   OMA; ARCHGGE; -.
DR   OrthoDB; 434648at2759; -.
DR   Proteomes; UP000006643; Partially assembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 2.
DR   InterPro; IPR052032; ATP-dep_AA_Ligase.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR040570; LAL_C2.
DR   PANTHER; PTHR43585:SF2; ATP-GRASP ENZYME FSQD; 1.
DR   PANTHER; PTHR43585; FUMIPYRROLE BIOSYNTHESIS PROTEIN C; 1.
DR   Pfam; PF13535; ATP-grasp_4; 2.
DR   Pfam; PF18603; LAL_C2; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 2.
DR   PROSITE; PS50975; ATP_GRASP; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT   DOMAIN          251..460
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   DOMAIN          710..913
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1015 AA;  111150 MW;  25B5C1E4422AD599 CRC64;
     MGNAAAKEAA TPPPAPAKEL PTQQKTEPSF RVLSADQRAI TFDERKHLRT GADARADRVT
     LGAMADFRPL QRAATFDPRL RSQKQLLTAS DVMHRRFFNA CERRVSTSAE RNLFRIAEGD
     KERQEAIVVV DPYSTGSTMA EKVLERGYLC VCVYSDTLEV TQERISHVPK ELASKFLAII
     YHDGEAERKD ASKALQDTSA ALRRVKNVDI VGIFAGAETG VLLADKLSEH FKLTTNGTSG
     SNARRNKYLM GEKVRASGLR AVAQVQAAKW SQVESFVKNE LIPMLKGGDF KVIVKPVESA
     GSDDVMLCHS MEEVRAAFGN IQGKINGLGL ENQATLVQEY LEGTEYVVDT VSRNGVTKVV
     AVWEYDKRAV NDAPFVYYGV LLRAAPDGSV LAKVADYVLK VVKALEIDHG PAHAEVKVVR
     GEPCLVEIGS RCHGGSGSYL PIVTPCLGYN HVDAALDSYL DAEAFERLPD RPKELKSYGC
     EAMLVSYETG KLAGYPGQQE IEELSSTVST VWYTHVGEEL KTTVDMFSTP GSVILVHKDE
     EQLIYDYGRI RELEHKGLYE LEPEEEAESK PKRLHGTVVV VDPFSTGAVL AHELMVRGYD
     CICVYSDRLE NIESVASLVP EGLTLEFAAT VAFEGNLDQT VSAIRKAATQ VADKRSKKKK
     QRVKASAAVC AVFAGAELGV KLADALIDAL GLEGNVLDHS NARRDKYLMG ETLRSAGVRA
     VKQVKAKTWA EAEDFITQDL KPEPFEVVLK PLESAGTEDV VLCLSIEEAQ RTFGGILGKI
     NGLGIQNDAV LLQEFLEGDE YVVDTVSRSG EHKVAAIWKY DKRRVNDAAF VYFGLSLVPA
     EGIINEMIDY QFQVLDALGI REGPAHGEVK FCGGSPVLIE VGSRCHGGEG AWVPIANMCV
     GYNQVTAAVD SILDGEAFAK LSDRPTKLLA YGCEAMLVSY KNGVLKSIPG IAEIEKMPAF
     LKKEIFVGPG DNMRQTVDMF TTPGSIMLTH KDHNVLERNL ARIRELEVEG LFEVE
//