ID   A0A9D3T039_MEGAT        Unreviewed;       367 AA.
AC   A0A9D3T039;
DT   03-MAY-2023, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2023, sequence version 1.
DT   05-FEB-2025, entry version 7.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAG7455086.1};
GN   ORFNames=MATL_G00252860 {ECO:0000313|EMBL:KAG7455086.1};
OS   Megalops atlanticus (Tarpon) (Clupea gigantea).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Elopiformes; Megalopidae; Megalops.
OX   NCBI_TaxID=7932 {ECO:0000313|EMBL:KAG7455086.1, ECO:0000313|Proteomes:UP001046870};
RN   [1] {ECO:0000313|EMBL:KAG7455086.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=YG-15Mar2019-1 {ECO:0000313|EMBL:KAG7455086.1};
RC   TISSUE=Brain {ECO:0000313|EMBL:KAG7455086.1};
RA   Zahm M., Roques C., Cabau C., Klopp C., Donnadieu C., Jouanno E.,
RA   Lampietro C., Louis A., Herpin A., Echchiki A., Berthelot C., Parey E.,
RA   Roest-Crollius H., Braasch I., Postlethwait J., Bobe J., Montfort J.,
RA   Bouchez O., Begum T., Mejri S., Adams A., Chen W.-J., Guiguen Y.;
RL   Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAG7455086.1}.
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DR   EMBL; JAFDVH010000024; KAG7455086.1; -; Genomic_DNA.
DR   OrthoDB; 8891580at2759; -.
DR   Proteomes; UP001046870; Chromosome 24.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   CDD; cd08330; CARD_ASC_NALP1; 1.
DR   FunFam; 1.10.533.10:FF:000013; Apoptosis-associated speck-like protein containing a CARD; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR001315; CARD.
DR   InterPro; IPR033516; CARD8/ASC/NALP1_CARD.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR051249; NLRP_Inflammasome.
DR   PANTHER; PTHR46985:SF2; APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD; 1.
DR   PANTHER; PTHR46985; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00619; CARD; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50209; CARD; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW   Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW   Reference proteome {ECO:0000313|Proteomes:UP001046870}.
FT   DOMAIN          8..277
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   DOMAIN          279..363
FT                   /note="CARD"
FT                   /evidence="ECO:0000259|PROSITE:PS50209"
SQ   SEQUENCE   367 AA;  41176 MW;  EED918F0F9B725AE CRC64;
     MCLSLLQDPT HKIKFTPEID HSNGKITYRY HSTHAVQFEC SVTGLVFVME MVGEVQYSTA
     LWDTSLLTAT GQQPAGPLFN IICPQGSVSE LHLPHCEVLS GDKCDFLSVA HVDGDSMEML
     QPLEVTDTHV RVKVRGFSSF GLIKSPSHSS IKGQVLLFLR QPDGDILNVL LLPRNIPISE
     VEPQQRGGLH IQVSSNCDLT PDRTYKLSCQ NHRTQPKSAP FDCEYGPNYH PTFEVFLDMP
     VREMNLRLQE RALKWSEVWT RLIRLPVPAP PAPPLPADSF IDQHMDNLIQ RVTLVKPFAD
     TLLSKGLIQE EAYAKICAAQ TSQEKMRELF QVLRAGGPEV KSTFYTLLTE KEPYLVKDLG
     AASVRRV
//