ID   A0A8C5B3F8_GADMO        Unreviewed;       523 AA.
AC   A0A8C5B3F8;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   05-FEB-2025, entry version 14.
DE   SubName: Full=Uncharacterized LOC115560657 {ECO:0000313|Ensembl:ENSGMOP00000041339.1};
GN   Name=LOC115560657 {ECO:0000313|Ensembl:ENSGMOP00000041339.1};
OS   Gadus morhua (Atlantic cod).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus.
OX   NCBI_TaxID=8049 {ECO:0000313|Ensembl:ENSGMOP00000041339.1, ECO:0000313|Proteomes:UP000694546};
RN   [1] {ECO:0000313|Ensembl:ENSGMOP00000041339.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2024) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   Ensembl; ENSGMOT00000025791.1; ENSGMOP00000041339.1; ENSGMOG00000025171.1.
DR   GeneTree; ENSGT00650000094113; -.
DR   OMA; LPPCEHC; -.
DR   Proteomes; UP000694546; Chromosome 16.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_dom.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR051249; NLRP_Inflammasome.
DR   PANTHER; PTHR46985:SF2; APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD; 1.
DR   PANTHER; PTHR46985; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694546}.
FT   DOMAIN          109..388
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   DOMAIN          431..504
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          1..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          389..428
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..84
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        389..398
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   523 AA;  58184 MW;  5FBE2E741A6F57D4 CRC64;
     MVAEMAHCEA ACRSGDGDGD VHTSDCKGNP AEVDSSDSEH SGTSVADSEE GSGSEEDEED
     RVDLEANEER DEEEEEVETG EDSSQEVLAE PASTGEEVHL KSQCEKCKAA QQSSDYEKVT
     PRKISKGRLL VRLEGEGTYE CSVTGLVFEV SEQALVRYSV LSWSKFDTFL PDSWKFAGPI
     FNVDVVNKDA SVLQSILFPH SLCLADPQYE LQFSVLHVTG SGPQLERSAE HSGSHVRWRV
     SSLSPVGPVV QSGRPLEHHG VVLVYKELSH SNTFSFRVYL ASNNSSDIKD IGTQVRSAQK
     SYRKIDKPPV CNLDVGKYHL VSQPEGEINP KELKFTFEII KLKGYFEAFF EQPPPFTLSL
     KETTTDETVW SATIREGDCE EVKMVFKPKQ KAGGRKRSSS TSEEEMANKK PCCVDESDGN
     NKNRPAGQVL SDKQLLQVAK TLGKEWEQAA IHLELSITDL DDIKADRQTE VAMQKLKMLE
     RWKRRRSPGK ATAQDLLRGL KDLEDLPVET HRLLTEMVQG PVK
//