ID   A0A8C3HYY0_CHRPI        Unreviewed;       484 AA.
AC   A0A8C3HYY0;
DT   19-JAN-2022, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2022, sequence version 1.
DT   05-FEB-2025, entry version 16.
DE   RecName: Full=Caspase recruitment domain-containing protein 8 {ECO:0008006|Google:ProtNLM};
OS   Chrysemys picta bellii (Western painted turtle) (Emys bellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Emydidae; Chrysemys.
OX   NCBI_TaxID=8478 {ECO:0000313|Ensembl:ENSCPBP00000025840.1, ECO:0000313|Proteomes:UP000694380};
RN   [1] {ECO:0000313|Ensembl:ENSCPBP00000025840.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2024) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   Ensembl; ENSCPBT00000030444.1; ENSCPBP00000025840.1; ENSCPBG00000018352.1.
DR   GeneTree; ENSGT00650000094113; -.
DR   Proteomes; UP000694380; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0000445; C:THO complex part of transcription export complex; IEA:TreeGrafter.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:TreeGrafter.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   FunFam; 1.10.533.10:FF:000088; P53-induced death domain protein 1; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_dom.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR021861; THO_THOC1.
DR   PANTHER; PTHR13265:SF1; CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 8; 1.
DR   PANTHER; PTHR13265; THO COMPLEX SUBUNIT 1; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694380}.
FT   DOMAIN          77..357
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   DOMAIN          400..484
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          1..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..11
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..58
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   484 AA;  55389 MW;  E99FAC6C2DC1F209 CRC64;
     MTSGQECQDV QGSGDDVSSL KAKVESYGTR EDDSAQECKS DTEETDIRKS DEALEKNELL
     PPVESEAHSQ FRCEHVKTEH NQKEQVTPRK LSRGQFWLKL EAEGTYQCTV TGLIFDVTKA
     AVIKYSVLSW SKYADYVKKP WIVGGPIFDV SCDTASVLTS IQFPHSLSLN DHESDMTFKV
     LHIKSTGPAI EPSVDHSMTH VKWHVSSLSP VGPVIQTQEP VHYNGAVILY KVVNNHPSLS
     FRVYVATNND SFIKDISNAV KHSDKKFIKI DKPPVCKKQL QDGKRYRLIS ESEAEITPEE
     IEFVDGSLLK LKSYFEVYLE QPMEFTLSLI ELESEEIVWK AKLRECDWIL HDQNKNERKR
     NAISNRRRKS SNSLSDEEFY NKRLKGRDIS DGTKAKTTLT DQQLMTLAKK MGKDWKEIGI
     ECLKLEMKDI QQIQAKEEEV NVHKFLMLEK WRKGEKSNGT AQNLYDSLKD HVSYEIIQIL
     EGFL
//