ID   A0A6F9C153_9TELE        Unreviewed;      1120 AA.
AC   A0A6F9C153;
DT   12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT   12-AUG-2020, sequence version 1.
DT   05-FEB-2025, entry version 17.
DE   RecName: Full=FIIND domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=CSTEINMANNI_LOCUS3427363 {ECO:0000313|EMBL:CAB1342448.1};
OS   Coregonus sp. 'balchen'.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Coregoninae; Coregonus.
OX   NCBI_TaxID=861768 {ECO:0000313|EMBL:CAB1342448.1, ECO:0000313|Proteomes:UP000502089};
RN   [1] {ECO:0000313|EMBL:CAB1342448.1, ECO:0000313|Proteomes:UP000502089}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   De-Kayne R.;
RL   Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   EMBL; LR778287; CAB1342448.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A6F9C153; -.
DR   OrthoDB; 3598281at2759; -.
DR   Proteomes; UP000502089; Chromosome 35.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0003924; F:GTPase activity; IEA:TreeGrafter.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR001315; CARD.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR045063; Dynamin_N.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR053082; Nuclear_GTPase_SLIP-GC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR47308; NUCLEAR GTPASE SLIP-GC; 1.
DR   PANTHER; PTHR47308:SF1; NUCLEAR GTPASE SLIP-GC; 1.
DR   Pfam; PF00619; CARD; 1.
DR   Pfam; PF00350; Dynamin_N; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50209; CARD; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000502089}.
FT   DOMAIN          774..1045
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   DOMAIN          1054..1120
FT                   /note="CARD"
FT                   /evidence="ECO:0000259|PROSITE:PS50209"
FT   REGION          82..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          290..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..100
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..129
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..306
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1120
FT                   /evidence="ECO:0000313|EMBL:CAB1342448.1"
SQ   SEQUENCE   1120 AA;  127979 MW;  95AC09ABC4C85EEA CRC64;
     MASFDFVRDK LTEWNHSDFI QRFEDEEIDE EGFLSLEETD LINLIPKTGP RSRFRKKYNT
     FLKVTGEMVN QEPCQKAIKT PLRNEPSKCP ETKRSMDKPF GKPGGSVPVT DTSGVGETVY
     DQSEPSTSKI PPLQVNIPGK RKSDETHANK QTKKRQRGAA SRITETFEIE TKTEVKKIMQ
     RVKSKLDDLP STKLIDFLRG KIQTLEKEKK EIVGVFGKTG AGKSFLINTI LGETKLLPFG
     NQGACTSVMI QVEANMTDSD SKYIAEIEFM TEEEWKEELW SIFRDRSYED GNDEDQERDD
     DDDDDDKISS LYGKDGRGAT LEELMDRKHF REIPEFRLSV KKRFLCDTAE ELSEKITCYT
     RSDTQSDTFK RQYWPLVKCI TIKVPNSKDL LEHVVLVDLP GNGDCNKSRD EMWKSFVGNC
     SAVWIISGIA RASSEKESWE ILDSTVSLFG PGGECRSISF ICTKTDEDIQ NDDARTCILR
     RNKTTKKQVR EKFSKQRLIK KHFSGGKDFL QVFTVSSMEY QKEKHLQQEE TEIPKLQEFL
     RNLNDHHKKT SDYVSGAYGI LSLIQGAKSS DMTDSKEEVC QVLEQRLKEE IKFIGQTMDD
     AYKDFEQCLS EGVKQSEESC EKLMNKVIAP RGKKGSGYHK VVKTLCKNGG VYKPKGKKEI
     NLNESLASCM RSLIDEEFKR YFPNEGKRGP IRERIDDFTL DTNSLVGKHL ELLLHLTFLK
     TEETVLKAKL ICDIREKKKK IYSTLTESEH IVMQLKCKLQ ESMDLSLKTP NSSFLPDVTV
     EYNKMKMCYE KLMSCKPTNR LQCPKAGIFP CISTGLVFLM EGKGDVVSMM TQWDRSLLGS
     RIPAGPLFSI ECPEQSVRQL HLPHCMCDGE NDILSVAHII DGNMEIFHPF KTTATHVIVN
     ITHLSLFGLI RNRFSFHPVQ SQVLLFLQPQ GNRPQKCILN VFLLPNNVPL CEVERQQRGS
     TFIQTSSNCT LTPRGKYGLC CELSGQFDYD YSPNFHPTFQ VFLDCMLGAE NIRLRLLDRG
     RNDQRVWECL VPTDFEPPQI NPINPNPGAE AELNQLSGEE FVDNHMADLI QRVTMVRSVS
     DYLLAKNMIQ DEMCARIRRA STNQEQMRIM FEAVRAGGPR
//