ID   A0A3Q2V2C9_HAPBU        Unreviewed;       439 AA.
AC   A0A3Q2V2C9;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   05-FEB-2025, entry version 25.
DE   RecName: Full=FIIND domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Haplochromis burtoni (Burton's mouthbrooder) (Chromis burtoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Haplochromis.
OX   NCBI_TaxID=8153 {ECO:0000313|Ensembl:ENSHBUP00000004937.1, ECO:0000313|Proteomes:UP000264840};
RN   [1] {ECO:0000313|Ensembl:ENSHBUP00000004937.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2024) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   AlphaFoldDB; A0A3Q2V2C9; -.
DR   STRING; 8153.ENSHBUP00000004937; -.
DR   Ensembl; ENSHBUT00000007842.1; ENSHBUP00000004937.1; ENSHBUG00000006282.1.
DR   GeneTree; ENSGT00730000111912; -.
DR   OMA; CAWERRV; -.
DR   Proteomes; UP000264840; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR001315; CARD.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR051249; NLRP_Inflammasome.
DR   PANTHER; PTHR46985:SF2; APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD; 1.
DR   PANTHER; PTHR46985; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50209; CARD; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW   Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264840}.
FT   DOMAIN          77..360
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   DOMAIN          356..421
FT                   /note="CARD"
FT                   /evidence="ECO:0000259|PROSITE:PS50209"
SQ   SEQUENCE   439 AA;  49982 MW;  8B512815CF71DCF2 CRC64;
     MLHLQPIVLP VMCWPCEADR RGPKRRLKHK SLEEIKHTGA ITYNAMIQNK DRRQSLTTTQ
     RRTDLTQATC SPDMKPQSCF EEFTPIITAD ESDDEAYLFQ CSSAGLYQCS VTGLVFVMKA
     EGDVVYRTVP WNRRLLAQHH KKPAGPLFDI KCQQQSVCQL CLPHCELIST GGGQFLKVAH
     VDNLEDIEFI TPHQITETHV VINITGFSGY GNVRDENSPA EPVQAMVLLF YKPPEELNLR
     SFLNVLLLPR NIVIHDVKNQ RRELVGEEMY IDVPSKCILY PKQVYTLSTV PDDDLIIVQP
     NEAEFNEEYP NYSITTFQVI LKTIITDINL SVTHKGSSSC IWEREVCLLP NRVRSMTASP
     KKRLLNVRSS FIDRISGPVL SSLIDKLLEK GLMVDGDREE ADAMQSRSDR ARFVIDTVRR
     KELHQPKTSL STSHSVIFR
//