ID   A0A3Q3BCN6_KRYMA        Unreviewed;       470 AA.
AC   A0A3Q3BCN6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   05-FEB-2025, entry version 25.
DE   SubName: Full=Uncharacterized LOC108240959 {ECO:0000313|Ensembl:ENSKMAP00000027255.1};
OS   Kryptolebias marmoratus (Mangrove killifish) (Rivulus marmoratus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae; Kryptolebias.
OX   NCBI_TaxID=37003 {ECO:0000313|Ensembl:ENSKMAP00000027255.1, ECO:0000313|Proteomes:UP000264800};
RN   [1] {ECO:0000313|Ensembl:ENSKMAP00000027255.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2024) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   AlphaFoldDB; A0A3Q3BCN6; -.
DR   Ensembl; ENSKMAT00000027597.1; ENSKMAP00000027255.1; ENSKMAG00000020175.1.
DR   GeneTree; ENSGT00650000094113; -.
DR   Proteomes; UP000264800; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01670; Death; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_dom.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR051249; NLRP_Inflammasome.
DR   PANTHER; PTHR46985:SF2; APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD; 1.
DR   PANTHER; PTHR46985; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00531; Death; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264800}.
FT   DOMAIN          70..354
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   DOMAIN          375..447
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          13..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        27..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   470 AA;  52947 MW;  7E477F58281D6C6D CRC64;
     QQVLHMLIYC AENGGTSAED SSEEDEDKNK AEDDSGEGHA RDSVQMFLLA FGISCASNST
     SFQTNGTFQN RSWKIYEQSS VIQSVCVCVR LQLEEEGTYE CSVTGLVFEA SQRVLVRYSV
     LSWSKFGAFL PNSWKCAGPI FNVDTVDKDA SALKSIQFPH SVCLAHPEED MTFRVLHIKD
     NRPLLEPTSD HTGSHVKWNV SSLSPVGPIL QTNGAVEHHG VVLVYKQLCS DANSYSFHVY
     LATNSASDIK VSVSANWCFR KNRYLRIDKP PTCKLDEGTY RLLSKPEGEI KPQVCLFDLK
     FTLAVTKMKG YFEAFFEQPP PFKLSLIEIN TEQTVWDATI REGTSARGLG AESFLGLLNG
     ISFFSGDCVE NVEKKPRKRT ILSKQLGMEW KQVAIFLGLE YRELDDIQAA EKEVNMQKLK
     MLLVWKKRRR PGEATAAHLL KNLEEVEEVP NEVYQILKGT TRQTYTYSLI
//