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Database: UniProt
Entry: A0A328TQD9_9GAMM
LinkDB: A0A328TQD9_9GAMM
Original site: A0A328TQD9_9GAMM 
ID   A0A328TQD9_9GAMM        Unreviewed;        78 AA.
AC   A0A328TQD9;
DT   10-OCT-2018, integrated into UniProtKB/TrEMBL.
DT   10-OCT-2018, sequence version 1.
DT   27-NOV-2024, entry version 17.
DE   RecName: Full=Major outer membrane lipoprotein Lpp {ECO:0000256|HAMAP-Rule:MF_00843};
GN   Name=lpp {ECO:0000256|HAMAP-Rule:MF_00843,
GN   ECO:0000313|EMBL:RAP69984.1};
GN   ORFNames=ACZ87_03218 {ECO:0000313|EMBL:RAP69984.1};
OS   Candidatus Erwinia dacicola.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=252393 {ECO:0000313|EMBL:RAP69984.1, ECO:0000313|Proteomes:UP000244334};
RN   [1] {ECO:0000313|EMBL:RAP69984.1, ECO:0000313|Proteomes:UP000244334}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Oroville {ECO:0000313|EMBL:RAP69984.1,
RC   ECO:0000313|Proteomes:UP000244334};
RA   Estes A.M., Hearn D.J., Agarwal S., Pierson E.A., Dunning-Hotopp J.C.;
RT   "Genomes of the Obligate Erwinia dacicola and Facultative Enterobacter sp.
RT   OLF Endosymbionts of the Olive Fruit fly, Bactrocera oleae.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: A highly abundant outer membrane lipoprotein that controls
CC       the distance between the inner and outer membranes. The only protein
CC       known to be covalently linked to the peptidoglycan network (PGN). Also
CC       non-covalently binds the PGN. The link between the cell outer membrane
CC       and PGN contributes to maintenance of the structural and functional
CC       integrity of the cell envelope, and maintains the correct distance
CC       between the PGN and the outer membrane. {ECO:0000256|HAMAP-
CC       Rule:MF_00843}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000256|HAMAP-Rule:MF_00843}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC       Rule:MF_00843}; Lipid-anchor {ECO:0000256|HAMAP-Rule:MF_00843};
CC       Periplasmic side {ECO:0000256|HAMAP-Rule:MF_00843}. Secreted, cell wall
CC       {ECO:0000256|HAMAP-Rule:MF_00843}; Peptidoglycan-anchor
CC       {ECO:0000256|HAMAP-Rule:MF_00843}. Note=Attached via its lipidated N-
CC       terminus to the inner leaflet of the outer membrane. Attached to the
CC       peptidoglycan network (PGN) via its C-terminus. {ECO:0000256|HAMAP-
CC       Rule:MF_00843}.
CC   -!- SIMILARITY: Belongs to the Lpp family. {ECO:0000256|HAMAP-
CC       Rule:MF_00843}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|HAMAP-Rule:MF_00843}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RAP69984.1}.
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DR   EMBL; LJAM02000506; RAP69984.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A328TQD9; -.
DR   Proteomes; UP000244334; Unassembled WGS sequence.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0042834; F:peptidoglycan binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030258; P:lipid modification; IEA:UniProtKB-UniRule.
DR   GO; GO:0043580; P:periplasmic space organization; IEA:UniProtKB-UniRule.
DR   FunFam; 1.20.5.190:FF:000002; Major outer membrane lipoprotein; 1.
DR   Gene3D; 1.20.5.190; -; 1.
DR   HAMAP; MF_00843; Lpp; 1.
DR   InterPro; IPR006817; Lipoprotein_leucine-zipper_dom.
DR   InterPro; IPR016367; MOM_Lpp.
DR   NCBIfam; NF040598; Ala_zip_lipo; 1.
DR   PANTHER; PTHR38763:SF1; MAJOR OUTER MEMBRANE LIPOPROTEIN LPP; 1.
DR   PANTHER; PTHR38763; MAJOR OUTER MEMBRANE PROLIPOPROTEIN LPP; 1.
DR   Pfam; PF04728; LPP; 1.
DR   PIRSF; PIRSF002855; Murein-lipoprotein; 1.
DR   SUPFAM; SSF58042; Outer membrane lipoprotein; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW   Rule:MF_00843}; Cell wall {ECO:0000256|HAMAP-Rule:MF_00843};
KW   Coiled coil {ECO:0000256|HAMAP-Rule:MF_00843};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288, ECO:0000256|HAMAP-
KW   Rule:MF_00843};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00843};
KW   Palmitate {ECO:0000256|ARBA:ARBA00023139, ECO:0000256|HAMAP-Rule:MF_00843};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088, ECO:0000256|HAMAP-
KW   Rule:MF_00843}; Reference proteome {ECO:0000313|Proteomes:UP000244334};
KW   Repeat {ECO:0000256|HAMAP-Rule:MF_00843};
KW   Secreted {ECO:0000256|HAMAP-Rule:MF_00843};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..78
FT                   /note="Major outer membrane lipoprotein Lpp"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016287278"
FT   DOMAIN          26..78
FT                   /note="Lipoprotein leucine-zipper"
FT                   /evidence="ECO:0000259|Pfam:PF04728"
FT   REPEAT          38..48
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00843"
FT   COILED          27..75
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00843"
FT   MOD_RES         78
FT                   /note="N6-murein peptidoglycan lysine"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00843,
FT                   ECO:0000256|PIRSR:PIRSR002855-1"
FT   LIPID           21
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00843"
FT   LIPID           21
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00843,
FT                   ECO:0000256|PIRSR:PIRSR002855-2"
SQ   SEQUENCE   78 AA;  8412 MW;  1EBA3D4AD09F6CE9 CRC64;
     MNRTKLVLGA VILSSTLLAG CSSNAKIDQL STDVQTLNAK VDQLSNDVNA IRSDVQAAKD
     DAARANQRLD NQAHSYRK
//
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