ID   A0A2H5B7M7_9ACTN        Unreviewed;       823 AA.
AC   A0A2H5B7M7;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   05-FEB-2025, entry version 23.
DE   RecName: Full=ATP-grasp domain-containing protein {ECO:0000259|PROSITE:PS50975};
GN   ORFNames=CFP65_5723 {ECO:0000313|EMBL:AUG80415.1};
OS   Kitasatospora sp. MMS16-BH015.
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Kitasatospora.
OX   NCBI_TaxID=2018025 {ECO:0000313|EMBL:AUG80415.1, ECO:0000313|Proteomes:UP000239175};
RN   [1] {ECO:0000313|EMBL:AUG80415.1, ECO:0000313|Proteomes:UP000239175}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMS16-BH015 {ECO:0000313|EMBL:AUG80415.1,
RC   ECO:0000313|Proteomes:UP000239175};
RA   Kim S.B., Yun B.-R.;
RT   "Genome sequence of Kitasatospora sp. MMS16-BH015.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP025394; AUG80415.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2H5B7M7; -.
DR   KEGG; kit:CFP65_5723; -.
DR   OrthoDB; 24041at2; -.
DR   Proteomes; UP000239175; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.40.50.20; -; 2.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 2.
DR   InterPro; IPR052032; ATP-dep_AA_Ligase.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR041472; BL00235/CARNS1_N.
DR   InterPro; IPR040570; LAL_C2.
DR   PANTHER; PTHR43585:SF2; ATP-GRASP ENZYME FSQD; 1.
DR   PANTHER; PTHR43585; FUMIPYRROLE BIOSYNTHESIS PROTEIN C; 1.
DR   Pfam; PF13535; ATP-grasp_4; 1.
DR   Pfam; PF18130; ATPgrasp_N; 1.
DR   Pfam; PF18603; LAL_C2; 1.
DR   SMART; SM01209; GARS_A; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 2.
DR   PROSITE; PS50975; ATP_GRASP; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000239175}.
FT   DOMAIN          115..314
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   DOMAIN          531..721
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
SQ   SEQUENCE   823 AA;  88203 MW;  65C7A475037984B6 CRC64;
     MVRVAIVEPR SSGCQLIDRA RELGHRVVVL TADEGERRIQ RRHLDGAAQT VVLDTNDDEA
     VRARLRTLHA QDPFAAVVPG FEHYVPVAAA AAAELGLPGI SARSATALRH KHVMRARVAE
     HGIDQPRHVL VSDEGQLAAS VRAVGLPCVV KPVDQSGSLN VVKAGTEAQA LAAFRRIHGY
     GSGYLGRTGL PLVLVEEYVA GPEYSVEGYV SSGEAVVLAV TEKHLGPEPW FVETGHLVPA
     PLADGPRAGV EEYARATVRA LGLELGPFHA ELRLGDRGPL LMEVAARLPG DRIPDLLRLA
     TGADLYELTL RCHLGLPGPR PVLRAGHAGV RYFQRPELDR YARMVVDEAV AADPAVREIG
     ALIAPGEPVP PPGSSAGRLG YVIATGPAPE AVTAALDAAE LGIAFEPLNP SEEPTVGRHV
     LILNRWNNKF AEYHRYLDHT VDRVAYLTTA AGQQPLDAGL AEHIRVVRDL SDRAEVSAAA
     LELQARYGQF THVLGLSEFD LELGAELREL LGVPGKGVED VRLVRDKVVM KAAVAEAGLR
     VPVNRPVRSA AEVRAFAAEH GYPFVLKPRA GADSQDVYVL RTPEATDQAL AQVELTAFQC
     EEFIEGNLYQ VDGVVSGGVL RTIRSWRCLG SCLDFATGTP FGSVANDDAE FEARVVEFTE
     GVLKALRLTD EVFHLEVFRA AGTDEIVFLE IGARAGGGQV RFVWEEVYGV DLIAASVQVQ
     LGIERAYPRA DIGGEVAGYL MMPEPPVRPA VVHRVASLTG AIPELYTEAL PPAGAVLDGN
     GGAVHTAGAF RFRAASSARV QEAIETAVKL YEMDWSPLEP SGV
//