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KEGG   Ursus americanus (American black bear): 123779716
Entry
123779716         CDS       T07931                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04015  Rap1 signaling pathway
uar04218  Cellular senescence
uar04620  Toll-like receptor signaling pathway
uar04664  Fc epsilon RI signaling pathway
uar04668  TNF signaling pathway
uar04714  Thermogenesis
uar04750  Inflammatory mediator regulation of TRP channels
uar04912  GnRH signaling pathway
uar04935  Growth hormone synthesis, secretion and action
uar04936  Alcoholic liver disease
uar05014  Amyotrophic lateral sclerosis
uar05022  Pathways of neurodegeneration - multiple diseases
uar05132  Salmonella infection
uar05135  Yersinia infection
uar05145  Toxoplasmosis
uar05161  Hepatitis B
uar05169  Epstein-Barr virus infection
uar05170  Human immunodeficiency virus 1 infection
uar05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    123779716 (MAP2K3)
   04668 TNF signaling pathway
    123779716 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123779716 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    123779716 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    123779716 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123779716 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    123779716 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123779716 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123779716 (MAP2K3)
   05161 Hepatitis B
    123779716 (MAP2K3)
   05169 Epstein-Barr virus infection
    123779716 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    123779716 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123779716 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123779716 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    123779716 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123779716 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123779716 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uar01001]
    123779716 (MAP2K3)
Enzymes [BR:uar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     123779716 (MAP2K3)
Protein kinases [BR:uar01001]
 Serine/threonine kinases: STE group
  STE7 family
   123779716 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Haspin_kinase Seadorna_VP7 APH RIO1 Choline_kinase DUF4344
Other DBs
NCBI-GeneID: 123779716
NCBI-ProteinID: XP_045634126
Position
Unknown
AA seq 347 aa
MESPDSSQPASMPQTKGKSKRKKDLRISCLSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSVVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgactccagtcagcccgccagcatgccccagaccaaagggaaatccaaa
aggaagaaggatttacggatatcctgcctgtccaagccgcccgtacccaaccccacaccc
ccccggaacctggactcccggaccttcatcaccatcggagacaggaactttgaggtggag
gccgatgacctggtgaccatctccgagctgggccgcggagcctatggggtggtggagaag
gtgcggcatgcccagagcggcaccatcatggccgtcaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcgtacggtcgactgc
ttctacaccgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgctcgataaaaacatgacc
attccagaggacatcctgggggaaattgctgtgtctgtcgtgagggcgttggaacacctg
cacagcaagttgtccgtgatccacagagacgtgaagccgtccaatgtcctcatcaacaag
gagggtcacgtgaagatgtgtgacttcggtatcagtggctacttggtggattctgtggcc
aagacgctggacgctggctgcaagccctacatggctcccgagagaatcaacccggagctg
aaccagaaaggctacaacgtcaagtccgacgtctggagcctcggcatcaccatgatcgag
atggccatcctccgctttccgtatgaatcctgggggactccgttccagcagctgaagcag
gtcgtagaggagccgtctccccagctccccgccgaccgtttctctcctgagtttgtggac
ttcactgcgcagtgcttgagaaagaaccccgcggagcgcatgagctacttggagctgatg
gagcacccgttcttcacattgcacaaaaccaagaagacggacattgctgcctttgtgaag
gagatcctgggggaggactcgtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (11)   
   Pfam (11)   
All databases (43)   

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