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KEGG   Ursus arctos (brown bear): 130542667
Entry
130542667         CDS       T05909                                 
Name
(RefSeq) carbonyl reductase [NADPH] 1-like isoform X1
  KO
K00079  carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
Organism
uah  Ursus arctos (brown bear)
Pathway
uah00590  Arachidonic acid metabolism
uah00790  Folate biosynthesis
uah00980  Metabolism of xenobiotics by cytochrome P450
uah01100  Metabolic pathways
uah05204  Chemical carcinogenesis - DNA adducts
uah05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:uah00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    130542667
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    130542667
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    130542667
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    130542667
   05208 Chemical carcinogenesis - reactive oxygen species
    130542667
Enzymes [BR:uah01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.184  carbonyl reductase (NADPH)
     130542667
    1.1.1.189  prostaglandin-E2 9-reductase
     130542667
    1.1.1.197  15-hydroxyprostaglandin dehydrogenase (NADP+)
     130542667
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase NAD_binding_4 Polysacc_synt_2
Other DBs
NCBI-GeneID: 130542667
NCBI-ProteinID: XP_057162818
Position
Unknown
AA seq 297 aa
MASASRVALVTGANKGIGFAIVQQLCRQFPGDVVLTARDEARGRAAVQQLQAEGLSPRFH
QLDIDDLQSIRVLRDFLRKEYGGLDVLVNNAGIVFKPADPTPLHIQAEVTMKTNFFGTRA
VCTELLPLMKAQGRVVNVSSIMSFAALKSCSPELQQKFMNETITEEELVGLMNKFVEDTK
KGVQQKEGWPDVNVLPYAVSKMGVTVLSRIHARNLSEQRRGDKILLNACCPGWVRTDMGG
PKGIKSPEEGAETPVYLALLPSDVERPHGDILMEKKVRRWGPISQLPSWAHSDPVII
NT seq 894 nt   +upstreamnt  +downstreamnt
atggcgtcagcctcccgagtggcgctggtgaccggggccaacaagggcatcggcttcgcc
atcgtgcagcagctgtgccggcagttcccgggggacgtggtgctcacggcgcgggacgag
gcgcggggccgggcagctgtgcagcagctccaggccgagggcctgagtccccgcttccac
cagctggacatcgacgacctgcagagcatccgggtcctgcgcgacttcctgcgcaaggag
tacgggggcctggacgtgctggtcaacaacgcgggcatcgtattcaagcctgctgatccc
acaccccttcatattcaagcagaagtgactatgaaaacaaacttctttggtacccgagct
gtgtgcacagaactgctgcctctaatgaaagcccaaggcagagtggtgaatgtgtctagc
ataatgagtttcgcagcccttaaatcatgcagcccagaactgcagcagaaatttatgaat
gagaccatcacagaggaggagctggtggggctcatgaacaagtttgtggaagacacaaag
aaaggagtacagcagaaggagggatggcctgatgtaaacgtactcccatatgcagtgtcc
aagatgggtgtcacggtcctgtccagaatccatgccaggaacctgagtgagcagaggaga
ggggacaagatcctcctgaatgcctgctgccctgggtgggtgagaacagacatgggtgga
ccaaaaggcatcaaaagcccagaagaaggagcagagacccctgtctacttggctcttttg
ccctcggatgttgagaggcctcatggagacattcttatggagaagaaagttcgacgatgg
ggacccatctctcagttaccttcctgggcccactctgatcccgtcatcatctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (7)   
   KEGG ENZYME (3)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (40)   

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