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KEGG   Trichosurus vulpecula (common brushtail): 118843532
Entry
118843532         CDS       T10126                                 
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp00562  Inositol phosphate metabolism
tvp01100  Metabolic pathways
tvp01521  EGFR tyrosine kinase inhibitor resistance
tvp04012  ErbB signaling pathway
tvp04014  Ras signaling pathway
tvp04020  Calcium signaling pathway
tvp04062  Chemokine signaling pathway
tvp04064  NF-kappa B signaling pathway
tvp04066  HIF-1 signaling pathway
tvp04070  Phosphatidylinositol signaling system
tvp04072  Phospholipase D signaling pathway
tvp04360  Axon guidance
tvp04370  VEGF signaling pathway
tvp04380  Osteoclast differentiation
tvp04611  Platelet activation
tvp04613  Neutrophil extracellular trap formation
tvp04625  C-type lectin receptor signaling pathway
tvp04650  Natural killer cell mediated cytotoxicity
tvp04662  B cell receptor signaling pathway
tvp04664  Fc epsilon RI signaling pathway
tvp04666  Fc gamma R-mediated phagocytosis
tvp04670  Leukocyte transendothelial migration
tvp04722  Neurotrophin signaling pathway
tvp04750  Inflammatory mediator regulation of TRP channels
tvp04919  Thyroid hormone signaling pathway
tvp04933  AGE-RAGE signaling pathway in diabetic complications
tvp04935  Growth hormone synthesis, secretion and action
tvp05167  Kaposi sarcoma-associated herpesvirus infection
tvp05169  Epstein-Barr virus infection
tvp05170  Human immunodeficiency virus 1 infection
tvp05171  Coronavirus disease - COVID-19
tvp05200  Pathways in cancer
tvp05205  Proteoglycans in cancer
tvp05206  MicroRNAs in cancer
tvp05214  Glioma
tvp05223  Non-small cell lung cancer
tvp05225  Hepatocellular carcinoma
Module
tvp_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
Enzymes [BR:tvp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     118843532 (PLCG2)
Membrane trafficking [BR:tvp04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    118843532 (PLCG2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    118843532 (PLCG2)
SSDB
Other DBs
NCBI-GeneID: 118843532
NCBI-ProteinID: XP_036607097
Position
3:225707870..225882611
AA seq 1264 aa
MTTKINLDMLPEYEKSQIKRTLELGTVMTLFSLKKSNPERRTVQVITETRQVAWSKTADK
IEGFLDLMEIKEIRPGKNSKDFERGKASRQKEDCCFTIFYGTQFVLNTLSLAADSKEDAT
KWLCGLTILHQEAQSASTPAIIESWLRKQIYSVDQTRKNSISFRELKTILPLVNYKVSSA
KFLKDKFLEIGAYKDELSFEQFHLFYKKMMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQEIWAQDLSKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSKENS
IWDDKYDSVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTESYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVHAIRDHAFVSSQFPVILSIEEHCCVEQQRHMARV
FKEVFGDLLLTKPTEASADQLPSPAQLKEKIVIKHKKLGPRGDVDINIEDKKEEKKQQGE
LYMWDSIDQKWYRHYCAIADEKLSFSDVIEQNAEEDSVKDVSQTDLHFGEKWFHKRMEKR
TSAEKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTPEGGAMKYY
LTDNLMFNSIYDLIQHYREAHLRCAEFELRLTDPVPNPNPHESKAWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGGDAYAITFRAKGKVKHCRINKDGHHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNTERDINSLYDVRMYVDPSEINPSTPQRTVKALYDYK
AKRGDELSFCRGALIHNVSKEPGGWWKGDYGGRIQQYFPSNYVEDISTVDFEELEKQIIE
DNPLGSLCRGILDLNTYNVVKVPQGKNQKPFVFILEPKKPNDPPIEFATDKVEELFEWYQ
SIREITWKNATVETNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVET
KADSIVRQKPIDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYM
QLNHALFALNGRTGYVLQPESMRNENYDPTPPESQRKILMTLTVKVLGARHLPKLGRSIA
CPFIEVEICGTEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEEDM
FSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCR
QLRRRQEELNNQLFLYDTHQNLRNANRDALVNEFNVNENQLQLYQEKCNRRLREKRVSNS
KFYS
NT seq 3795 nt   +upstreamnt  +downstreamnt
atgaccaccaagatcaacttagacatgcttcctgaatatgagaaaagtcagatcaagcgg
accctggaactaggaactgtcatgaccctgtttagcctcaagaaatctaaccctgagagg
aggacagtccaggtcatcacggagaccaggcaggtggcctggagcaagacggctgacaag
atcgaaggattcttggacttaatggagataaaggaaatccgcccagggaaaaactcaaag
gactttgaacgtgggaaagccagtcgccagaaagaagattgctgctttaccatattttat
ggcacccagtttgtcctcaacactctgagtttagcagcggactccaaggaagatgctact
aaatggctttgtggcttgacaattttgcaccaagaagcccagagtgcctcgacgccagct
attattgagagctggctaagaaagcaaatttattctgtagatcaaactcggaaaaatagt
atcagcttcagagaactgaagaccattcttcccttagtaaactacaaagttagcagtgcc
aagttcctgaaagacaaattcctggaaataggtgcctacaaggatgaactcagctttgaa
cagttccacctattctacaaaaagatgatgtttgagcaacagaaatcaattcttgatgag
ttcaaaaaagattcgtctgtgtttattctgggaaatacagaccggccagatgcatctgcc
gttcacctgcatgacttccagaggtttctgctgcacgaacagcaggaaatatgggcacag
gatctaagtaaagtaagagagcggatgacaaaatttatagatgacacgatgagagaaaca
gctgagccgttcctgtttgtcgatgagttcctcacttacctgttttcaaaagaaaacagc
atttgggatgataaatatgattctgttgacatgcaagacatgaataatcccttgtctcat
tactggatttcttcatctcataacacgtacctcactggggaccaacttcgaagtgaatct
tctactgaatcatacattcgatgtcttcgaatgggttgccggtgtatagagttggattgc
tgggatgggcctgatgggaagccaatcatctatcatggctggacgcgaacgacgaaaatc
aagtttgatgatgtggtgcatgccatcagagaccatgcttttgtctcctcacagttccct
gtgatcctctccattgaagagcactgctgtgtagaacagcagcgtcatatggccagggtg
tttaaggaagtgtttggggacctcctccttacaaagcccactgaagccagtgccgaccag
ctgccgtcccctgcccagctgaaagaaaagattgtcatcaagcacaagaagctgggtccc
agaggagatgtggacatcaacattgaagacaagaaggaagaaaaaaaacagcaaggggaa
ttgtacatgtgggatagcattgatcagaagtggtatcgccactattgtgccatagctgat
gagaagctgtccttcagtgatgttatagagcagaatgcggaggaggattcagtaaaggat
gtgtcacagactgacttgcatttcggtgagaagtggtttcataagaggatggagaagagg
acaagtgctgagaaactgctacaggaatactgtgctgaaactgggggcaaggatgggacc
ttcttggtccgtgaaagtgagactttccccaatgactacacgctgtccttctggagatca
ggcagagtccagcactgtcgaatacggtcgactcctgagggaggggccatgaagtattat
ttgactgacaacctcatgttcaacagcatctatgacttgattcaacactaccgagaagcc
cacctgagatgtgcagaatttgagcttcgtctgacagacccagtgcccaaccccaatcct
catgaatcaaaagcttggtactatgatagcctgagcagaggagaagctgaagacatgttg
atgagaattccccgagacggagccttcctgattaggaaaagagaagggggagatgcatac
gccattactttcagagccaaggggaaagtgaaacattgccggattaacaaagacggtcac
cactttgtgctggggacgtctgcttactttgaaagtttggtggaattggtcagctactat
gaaaagcatgcgctctacaggaaaatgagactgcgctaccccgtgactccagagctgctg
gaacgttacaacacggaaagggacataaattcactctatgatgtcaggatgtatgtggat
cccagtgaaattaacccctcaacgccccagagaaccgtgaaggctttgtatgactacaaa
gccaagcgtggggatgagctcagcttctgtcggggggccctcatccacaatgtctccaag
gagcctggtggctggtggaagggtgattatggaggaaggattcagcaatatttcccatct
aattatgtggaggacatatcaacagttgattttgaagagctggaaaaacagattattgaa
gataaccctttaggatctctgtgcagaggaatcttggatcttaacacctataatgttgtg
aaagtaccacagggaaaaaaccagaagccatttgtcttcatcctggaaccgaagaaaccc
aatgatcctcccatagagtttgcgactgacaaagtggaagagctctttgagtggtaccag
agcatcagggaaatcacctggaagaatgcgacagtggagaccaacatgaagtattgggag
aagaatcaatcgattgctatagaactgtccgacttagtcgtctactgtaagccaacgagt
aaaaccaaggataatttagaaaatcctgatttcagagaaattcgctctttcgtggagacc
aaggctgacagcatcgttaggcagaagccaattgatctcttgaagtacaatcaaaaggga
ctgactcgggtctacccaaaaggtcaaagggtggactcatcaaattatgatccttttcga
ctttggctttgtggctctcagatggtcgctctgaatttccagacagcagataaatatatg
cagctgaatcatgctttatttgcactcaatggacggactggctatgtcctgcagcctgaa
agcatgaggaatgaaaactatgatccaacacccccggaatcacaaaggaagatcctgatg
accttgacggtgaaggtcctgggggcccgccatctacccaagcttggccgaagcattgcc
tgtccatttatagaggtggaaatttgtgggaccgagtatgataataacaaattcaagacg
actgtagtgaatgataatggcctgagtccagtctgggcgtctactcaggaaaaagtgaca
tttgaaatttatgacccaaatctcgcatttctacgttttgttgtttatgaggaggatatg
ttcagcgatcccaactttctggcacatgccacttatcccattaaaggaatcaaatcaggg
tttagatcagttcctcttaaaaacggttacagtgaagatatcgaactggcctccctcctg
gttttctgtgagatgcgtcctgtcttggaaagtgaagaagagctctattcttcctgtcgc
cagcttcgaagacggcaagaggagctgaataaccaactcttcttgtatgacactcatcag
aacttacgtaatgccaacagagatgccctggtgaatgaattcaacgtcaatgaaaatcag
ttgcagctgtatcaggaaaaatgcaaccggagattaagggagaagagagtcagtaacagc
aaattctactcctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (38)   
   KEGG PATHWAY (37)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
All databases (58)   

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