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KEGG   Sus scrofa (pig): 110256149
Entry
110256149         CDS       T01009                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X1
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc04010  MAPK signaling pathway
ssc04015  Rap1 signaling pathway
ssc04218  Cellular senescence
ssc04620  Toll-like receptor signaling pathway
ssc04664  Fc epsilon RI signaling pathway
ssc04668  TNF signaling pathway
ssc04714  Thermogenesis
ssc04750  Inflammatory mediator regulation of TRP channels
ssc04912  GnRH signaling pathway
ssc04935  Growth hormone synthesis, secretion and action
ssc04936  Alcoholic liver disease
ssc05014  Amyotrophic lateral sclerosis
ssc05022  Pathways of neurodegeneration - multiple diseases
ssc05132  Salmonella infection
ssc05135  Yersinia infection
ssc05145  Toxoplasmosis
ssc05161  Hepatitis B
ssc05169  Epstein-Barr virus infection
ssc05170  Human immunodeficiency virus 1 infection
ssc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    110256149 (MAP2K3)
   04668 TNF signaling pathway
    110256149 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110256149 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    110256149 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    110256149 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110256149 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    110256149 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110256149 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110256149 (MAP2K3)
   05161 Hepatitis B
    110256149 (MAP2K3)
   05169 Epstein-Barr virus infection
    110256149 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    110256149 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110256149 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110256149 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    110256149 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110256149 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110256149 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ssc01001]
    110256149 (MAP2K3)
Enzymes [BR:ssc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     110256149 (MAP2K3)
Protein kinases [BR:ssc01001]
 Serine/threonine kinases: STE group
  STE7 family
   110256149 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal APH Choline_kinase RIO1
Other DBs
NCBI-GeneID: 110256149
NCBI-ProteinID: XP_020923714
Position
12:61396337..61417333
AA seq 371 aa
MESPAASPPAGVPPPKGKSRRKKDLRISCMSKPPAPSPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKVSSPRPPSPGGPPASHLTAALAPQRIR
ATVNSQEQKRLLMDLDVNMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLE
KNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV
DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQ
QLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFASHKTRETDIA
AFVREILGEDS
NT seq 1116 nt   +upstreamnt  +downstreamnt
atggagtcgcccgccgcgagtcctcccgccggcgtgcccccgcccaaaggaaaatccagg
aggaagaaggacttacggatctcttgcatgtccaagccgccggcacccagccccacgccc
ccccggaacctggactcccggaccttcatcaccatcggagacaggaactttgaggttgag
gccgacgacctggtgaccatctcggagctgggccggggagcctacggggtggtggagaag
gtgcgccacgcccagagcggcaccatcatggccgtgaaggtgagcagcccccgccccccc
tcccctgggggcccccccgccagccacctgacggctgccctcgccccacagcgcatccgg
gccaccgtgaactcgcaggagcagaagcgcctgctcatggacttggacgtcaacatgcgc
acagtggactgtttttacaccgtcaccttctacggggccctgttcagagagggagatgtg
tggatctgcatggagctcatggacacgtccctggacaagttttaccggaaggtgctggag
aaaaacatgacgattccagaggacattctgggggaaattgctgtgtctatcgtgagggcc
ctggagcacctgcacagcaagctgtccgtgatccaccgagatgtgaagccatccaacgtc
ctcatcaacaaggagggccacgtgaagatgtgtgacttcgggatcagcggctacttggtg
gactccgtggccaagaccatggacgccggctgcaagccctacatggcgcccgagaggatc
aatccagagctgaaccagaaaggctacaatgtcaagtctgatgtctggagtctgggcatc
accatgatcgagatggccatcctgcggtttccttatgagtcgtggggcaccccgttccag
cagctgaagcaggtggtggaggagccgtcccctcagctcccagctgaccgcttctccccc
gagtttgtggacttcaccgcacagtgcctgagaaagaaccccgcagaacgcatgagctac
ctggagctgatggaacaccctttcttcgcctcgcacaaaaccagggagaccgacatcgct
gcctttgtgagggagatcctgggagaggactcgtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (9)   
   RefSeq(nuc) (7)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (63)   

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