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KEGG   Suncus etruscus (white-toothed pygmy shrew): 126033429
Entry
126033429         CDS       T09902                                 
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase-like
  KO
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
Organism
setr  Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr00140  Steroid hormone biosynthesis
setr01100  Metabolic pathways
setr04913  Ovarian steroidogenesis
setr04917  Prolactin signaling pathway
setr04927  Cortisol synthesis and secretion
setr04934  Cushing syndrome
Module
setr_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
setr_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
setr_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:setr00001]
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    126033429
   04917 Prolactin signaling pathway
    126033429
   04927 Cortisol synthesis and secretion
    126033429
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    126033429
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:setr00199]
    126033429
Enzymes [BR:setr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19  steroid 17alpha-monooxygenase
     126033429
    1.14.14.32  17alpha-hydroxyprogesterone deacetylase
     126033429
Cytochrome P450 [BR:setr00199]
 Cytochrome P450, animal type
  CYP17 family
   126033429
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 126033429
NCBI-ProteinID: XP_049646372
Position
17:complement(46678821..46685413)
AA seq 501 aa
MWELLMLLVLSLTYFFWPKLKSSDVKYPQSLPSLPLVGSLPFLPRHGEQHVNFFKLQEKY
GPIYSFRLGTKTTVMVGHHQLAKEVLIKKGKEFSGRPQLVTLDILSNNQKGIAFANHRAW
QLHRKLVQATFALFKDGSQRLEKTICQEISLMCDSLTTLDGQSINMFDLIFLMMANVICT
ICFNLSYKLGDPEPEIMQKFTKGILDSLGQETIVNIFPVLKVFPNKTLEKLKKSVNIRNE
LLIKILEKYKENYTGDSTTSMMDILIQAKTNYANSNSTLLSDEYILATMGDIFGAGVETT
TSVILWIIAYLLHHPQLKKRIQEEIDQNVGFSRTPNIRDRNHLLLLEATIREVLRIQPLA
PLLIPHQAMVDSSISKFAIDKGTDVIINLWALHHNDKEWAQPDQFIPERFLDPTRSHLIN
PSLSYLPFGAGPRSCVGEMLARQEMFLTMAWLLQKFDLDVPDDGKLPSLEGSVKVVSLPS
AFKVKVQIRQAWKEAHAEGSL
NT seq 1506 nt   +upstreamnt  +downstreamnt
atgtgggagctgctgatgctcttagtgctcagcctcacctacttcttttggcccaagcta
aagtcttctgatgttaaatatccccaaagtctcccatcactacccctggttggcagcctg
ccattcctgcccaggcatggagagcaacacgtgaacttcttcaagctgcaggaaaaatat
ggccccatctattccttccggctgggcaccaagactacagtgatggttggccatcaccag
ctggccaaagaggtgctgatcaagaagggcaaggaattctctgggcggcctcaactggta
actcttgacatcctgtcgaacaaccagaagggcatcgcttttgctaatcacagagcctgg
cagctgcatcggaagctagtgcaagccaccttcgccctcttcaaggatggcagccagagg
ctggagaagaccatctgccaggaaatcagtttaatgtgtgattccctgaccaccctggat
ggacagtctataaatatgtttgatctcatcttcctgatgatggccaatgtgatctgtacc
atctgcttcaacttatcctacaaacttggagaccctgaacctgagatcatgcagaagttc
accaagggcatcttggattccttgggccaggagactattgtaaatatattccctgtgtta
aaggtttttcccaataaaaccctggaaaagttgaagaaaagcgtgaatattcgaaatgaa
cttctgattaaaatcttggaaaaatacaaggagaactacactggcgactctaccacgagc
atgatggacatactgatccaagccaagacaaattacgccaactcaaattccacattgctt
tctgatgagtatattctggccaccatgggtgatatctttggtgctggtgtggagaccacc
acgtctgttattctgtggataatcgcttacctgctgcatcaccctcagctgaagaagagg
atccaggaggagattgaccagaatgtgggtttcagccggacaccaaatatcagagaccgg
aaccacctcctgctcctggaagccaccatccgagaggtgctccgcatccagcccttggcc
ccgctgctcatcccccatcaggctatggttgactccagcatcagcaagttcgccattgac
aagggcacggatgtcatcatcaatctgtgggcactgcatcacaatgacaaggagtgggcc
cagcctgaccagttcatccctgagcgtttcctggacccgacccggagccatctcatcaat
ccttccctaagttacctgccttttggggctgggccccgctcctgtgtgggagaaatgctg
gcccgccaggagatgttcctcaccatggcctggcttctgcagaagttcgacttggatgta
ccagatgatgggaaactgccatccctagaaggttcagtcaaggtggtctctctgcccagt
gcattcaaagtgaaagtccagatacgccaggcctggaaggaagcccatgctgaggggagt
ctctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (6)   
   KEGG MODULE (4)   
Chemical substance (20)   
   KEGG COMPOUND (20)   
Chemical reaction (11)   
   KEGG ENZYME (2)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (51)   

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