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KEGG   Phocoena sinus (vaquita): 116762723
Entry
116762723         CDS       T07759                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
psiu  Phocoena sinus (vaquita)
Pathway
psiu04010  MAPK signaling pathway
psiu04020  Calcium signaling pathway
psiu04022  cGMP-PKG signaling pathway
psiu04024  cAMP signaling pathway
psiu04218  Cellular senescence
psiu04260  Cardiac muscle contraction
psiu04261  Adrenergic signaling in cardiomyocytes
psiu04270  Vascular smooth muscle contraction
psiu04530  Tight junction
psiu04713  Circadian entrainment
psiu04723  Retrograde endocannabinoid signaling
psiu04724  Glutamatergic synapse
psiu04725  Cholinergic synapse
psiu04726  Serotonergic synapse
psiu04727  GABAergic synapse
psiu04728  Dopaminergic synapse
psiu04911  Insulin secretion
psiu04912  GnRH signaling pathway
psiu04921  Oxytocin signaling pathway
psiu04924  Renin secretion
psiu04925  Aldosterone synthesis and secretion
psiu04927  Cortisol synthesis and secretion
psiu04929  GnRH secretion
psiu04930  Type II diabetes mellitus
psiu04934  Cushing syndrome
psiu04935  Growth hormone synthesis, secretion and action
psiu04973  Carbohydrate digestion and absorption
psiu05010  Alzheimer disease
psiu05020  Prion disease
psiu05022  Pathways of neurodegeneration - multiple diseases
psiu05031  Amphetamine addiction
psiu05207  Chemical carcinogenesis - receptor activation
psiu05410  Hypertrophic cardiomyopathy
psiu05412  Arrhythmogenic right ventricular cardiomyopathy
psiu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:psiu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    116762723 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    116762723 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    116762723 (CACNA1D)
   04929 GnRH secretion
    116762723 (CACNA1D)
   04921 Oxytocin signaling pathway
    116762723 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    116762723 (CACNA1D)
   04924 Renin secretion
    116762723 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    116762723 (CACNA1D)
   04927 Cortisol synthesis and secretion
    116762723 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    116762723 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    116762723 (CACNA1D)
   04727 GABAergic synapse
    116762723 (CACNA1D)
   04725 Cholinergic synapse
    116762723 (CACNA1D)
   04728 Dopaminergic synapse
    116762723 (CACNA1D)
   04726 Serotonergic synapse
    116762723 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    116762723 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    116762723 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    116762723 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116762723 (CACNA1D)
   05020 Prion disease
    116762723 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    116762723 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    116762723 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    116762723 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    116762723 (CACNA1D)
   05414 Dilated cardiomyopathy
    116762723 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    116762723 (CACNA1D)
   04934 Cushing syndrome
    116762723 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:psiu04040]
    116762723 (CACNA1D)
Ion channels [BR:psiu04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   116762723 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 116762723
NCBI-ProteinID: XP_032505967
Ensembl: ENSPSNG00000022189
Position
11:complement(35236347..35560378)
AA seq 2159 aa
MMMMMMMKKMQHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSVPAPVGSLSQRKRQQYAKSKKQGNSSSSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGENQGCCGSLWCWWRRRGATKAGPSGCRRWGQAISKSKLSRRWRRWNRFSRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEINQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRMSELNMKEKITPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
IYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSRMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIVDVALSEADNSEESNRISI
TFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKV
AMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEEYTC
GSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPE
AKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVR
TALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDY
FRKFKKRKEQGLVGKYPAKSSTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETKGEEE
EDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNS
VCHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKRPSIGNLEHVSENGHHSFHKHGREP
QRRSSIKRADSGDEQFPTICREDPEIHGYFRDPCCLGEQEYFSSEECYEDDSSPTGSRQS
YSCGYYTRYPGSSLDFERPRGYHHPQSFSEDDDSPVCYDSRRSPRRRLLPPTPTSPRRSS
FNFECLRRHSSQEEFPPSPAFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWA
TPPATPSYRDWTPCYTPLIQVERSEAPDQVNGSLPSLHRSSWYTDEPGVSYRTFTPASLT
VPSSFHNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESA
ASNLLNGNVHPRANGDVGPVSRRQDYELQDFGPGYSDEEPDPGRDEEDLADEMICITTL
NT seq 6480 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccaggctccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaaccgtcctgtcttggcaagccgcgatcgacgctgct
agacaggccaaggctgcccaaactatgagcacctctgtacccgcacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccagcagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgc
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgaaacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttagaaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggcaaccactccagtggcaaatcgggaggctttgatgtcaaagccctccgc
gcctttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccatcataaaagccatggttcccctccttcacatagcccttttggtgttattt
gtaatcataatctatgctattataggattggaactttttattgggaaaatgcacaaaaca
tgtttttttgctgactcagatatcgtagctgaggaggacccagcaccgtgtgcgttctca
gggaatggacgccagtgtaccgccaatggcacggagtgcaggagtggctgggttggcccc
aatggcggcatcaccaactttgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattctcaaaggaaagggagaaggcaaaagcgcgggga
gacttccagaagctgcgggagaagcagcagctggaagaggatctcaagggctacttggat
tggatcacccaagcagaagacattgatcccgagaacgaagaagaaggaggagaggaaagc
aaacgaaataccagcatgcccaccagtgagacggagtctgtgaacacggagaacgtgagt
ggggaaggcgagaaccaaggctgctgtgggagcctctggtgctggtggagaagaagaggc
gccaccaaggccgggccctctgggtgtcggcggtggggtcaagccatctcaaagtccaag
ctcagccgacgctggcgccgctggaaccgcttcagtcgcagaaggtgtagggctgccgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctctgagcactacaaccagcctgactggttgacacagattcaagatattgctaacaaa
gtcctcttggctctgttcacctgcgagatgcttgtaaagatgtacagcttgggtctccag
gcatatttcgtctctcttttcaatcggtttgattgcttcgtggtgtgtggaggaattact
gaaacgatcttggtggaactggaaatcatgtctcctctgggcatctctgtgtttcgctgt
gttcggctcttgagaattttcaaagtgaccaggcactggacctccctgagcaacttggtg
gcatccttgttaaactccatgaagtccatcgcttcgctgctgcttctgctttttctcttc
atcatcatcttttccttgctggggatgcagctgttcggcggcaagtttaattttgacgaa
acgcaaaccaagcggagcacctttgataatttccctcaagcgcttctaaccgtgttccag
attctgacaggtgaagactggaatgctgtgatgtacgatggcattatggcctacgggggc
ccgtcgtcttcgggaatgatcgtctgcatctacttcatcatcctcttcatttgtggtaac
tatattctactgaatgtcttcttggccatcgctgtagacaacttggcagacgctgaaagt
ttgaatactgctcagaaagaggaagctgaagaaaaggaaaggaagaagattgccagaaaa
gaaagcctggaaaataaaaagaacaacaaaccagaaatcaaccagatagccaacagtgac
aacaaggtcaccatcgatgactaccgagaagaagatgaggacaaagacccctacccgcct
tgtgatgtgccagtaggtgaagaggaagaggaggaggaagaggatgaacccgaggttcct
gctggcccccgtcctcgaagaatgtctgagttgaacatgaaagagaaaatcacccccatc
cccgaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaaccttatcctcgtcttcatcatgctgagcagc
gctgccctcgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttgaagatgacgact
ttcggagctttcctccacaaaggggctttctgcaggaactacttcaacttactggatatg
ctggtcgttggggtgtctctggtgtcatttgggatccaatccagtgccatctcagttgtg
aagatcctgagagtcttaagggttctgagaccgctcagggcaatcaacagagcaaaagga
cttaagcacgtggtccagtgcgtctttgtggccatccggacaatcggcaatatcatgatc
gtcaccaccctcctccagttcatgtttgcttgcatcggggtgcagctcttcaaggggaag
ttttatcgatgcacagatgaagccaaaagtaaccccgaagaatgcagggggctcttcatc
ctctacaaggatggggatgtcgataaccctgtggtccgtgagaggatctggcaaaacagc
gacttcaactttgacaacgtcctctcagctatgatggctctgttcacggtctccacgttc
gagggctggcccgcgttgctgtacaaagccatcgactcgaacggagagaacgtcggcccc
atctacaactaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtagcg
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggggag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgagtacatgatgtttgtcctcatcatgctcaacactctc
tgcttggccatgcagcactacgagcagtccaggatgtttaatgacgccatggacatcctg
aacatggtgttcaccggggtgttcactgtcgagatggttttgaaagtcattgcatttaaa
cctaaggggtactttagtgatgcctggaacacgtttgactccctcatcgtaatcggcagc
attgtagacgtggcgctcagcgaagctgacaactctgaagagagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcgattggtgaagcttctcagcaggggggaaggc
atccggacactgctgtggacttttattaagtccttccaggcgctcccgtatgtcgccctt
ctcatcgccatgctgttcttcatctacgcggtgatcggcatgcagatgtttgggaaagtt
gccatgagagataacaaccagatcaacaggaacaacaatttccagacctttccccaagca
gtactgctgctcttcaggtgtgcgacgggggaggcctggcaggaaatcatgctggcctgc
ctcccgggaaagctctgtgaccccgagtccgattacaaccccggggaggagtacacctgc
gggagcaactttgccattgtctatttcatcagtttttacatgctctgcgcatttctgatc
atcaacctgtttgtggctgtcatcatggacaatttcgattatctgacccgggactggtct
atactggggcctcaccatttagacgaattcaaaagaatatggtccgaatatgaccccgag
gcaaagggaagaatcaagcacctggacgtggtcactctgctccgccgcatccagcccccc
ctggggttcgggaaattgtgtccacacagggtagcctgcaagagactagttgccatgaac
atgccgctcaacagtgatgggacagtcatgtttaatgcaactctgtttgctttggtccga
acggctcttaaaatcaagacggaagggaacctagaacaagctaatgaagaactccgagct
gtgatcaagaaaatctggaagaaaaccagcatgaaactacttgaccaagttgtccctcca
gctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaaacggaaagaacaaggactggtgggaaaataccccgcgaagagc
agcacaattgccctacaggcgggattaaggacactgcacgacattgggccagaaatccgg
cgtgctatctcatgtgatttgcaagatgacgagccggaggaaacaaaaggcgaagaagaa
gaagatgtgttcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gataggagagattcccttcagcagaccaataccacccaccgtcccctgcatgtccaaagg
ccttcaattccacctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcg
gtgtgtcataaccatcataaccataattccataggaaagcaagttcccagctcaacaaat
gccaatctcaataatgccaatatgtccaaagctgcccctggaaaacggcccagcattggg
aaccttgagcatgtgtctgaaaatgggcatcattccttccacaagcatggccgtgagcct
caaagaaggtccagtattaaaagggctgactcaggagacgagcagttcccaactatttgc
cgggaagacccagagatacacggctacttcagggacccctgctgcttgggggaacaggag
tacttcagcagtgaggagtgctacgaggacgacagctcgcccaccgggagcaggcagagc
tacagctgtggctactatacccgatacccaggcagcagcttggacttcgagcggcctcga
ggctaccatcacccccaaagcttctcggaggatgacgactcacctgtttgctatgactcc
cggaggtctccaaggagacgcctgctccctcccaccccaacatccccccggagatcctcc
ttcaacttcgagtgcctgcgccggcacagcagccaggaggagttcccgccatcccccgcc
ttcccccaccgcacggccctgcctctgcacctgatgcagcaacagatcatggcagtcgcc
ggcctagattccagtaaagcccagaagtactcgccaagccactccaccaggtcgtgggcc
accccgccagcgaccccgtcgtacagggactggacgccatgctacaccccactgatccag
gtcgagcggtcggaggccccggaccaggtcaacggcagcctaccatccctgcaccgcagc
tcgtggtacacggacgagcccggcgtctcctatcggacgttcacaccagccagcctgacc
gtccccagcagcttccacaacaaaaacagcgacaagcagaggagcgcagacagcttggtg
gaggcggttctgatatccgaaggcttaggacggtatgcgagggacccaaaattcgtgtca
gcgacaaaacacgaaatcgccgatgcctgtgacctaaccatcgacgagatggagagtgca
gccagcaacctgctgaacgggaacgtgcatccccgggccaatggggacgtggggcccgtc
tcacgccggcaggactacgagctccaggacttcgggccgggctacagcgacgaggagcca
gaccccgggagggatgaggaggacctggcggatgaaatgatttgcatcaccaccctgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (5)   
   Pfam (5)   
All databases (51)   

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