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KEGG   Phodopus roborovskii (desert hamster): 127219179
Entry
127219179         CDS       T08852                                 
Symbol
Map2k3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
prob  Phodopus roborovskii (desert hamster)
Pathway
prob04010  MAPK signaling pathway
prob04015  Rap1 signaling pathway
prob04218  Cellular senescence
prob04620  Toll-like receptor signaling pathway
prob04664  Fc epsilon RI signaling pathway
prob04668  TNF signaling pathway
prob04714  Thermogenesis
prob04750  Inflammatory mediator regulation of TRP channels
prob04912  GnRH signaling pathway
prob04935  Growth hormone synthesis, secretion and action
prob04936  Alcoholic liver disease
prob05014  Amyotrophic lateral sclerosis
prob05022  Pathways of neurodegeneration - multiple diseases
prob05132  Salmonella infection
prob05135  Yersinia infection
prob05145  Toxoplasmosis
prob05161  Hepatitis B
prob05169  Epstein-Barr virus infection
prob05170  Human immunodeficiency virus 1 infection
prob05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
prob05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:prob00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    127219179 (Map2k3)
   04668 TNF signaling pathway
    127219179 (Map2k3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    127219179 (Map2k3)
   04664 Fc epsilon RI signaling pathway
    127219179 (Map2k3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    127219179 (Map2k3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    127219179 (Map2k3)
  09159 Environmental adaptation
   04714 Thermogenesis
    127219179 (Map2k3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127219179 (Map2k3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    127219179 (Map2k3)
   05161 Hepatitis B
    127219179 (Map2k3)
   05169 Epstein-Barr virus infection
    127219179 (Map2k3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    127219179 (Map2k3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    127219179 (Map2k3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    127219179 (Map2k3)
   05022 Pathways of neurodegeneration - multiple diseases
    127219179 (Map2k3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127219179 (Map2k3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    127219179 (Map2k3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:prob01001]
    127219179 (Map2k3)
Enzymes [BR:prob01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     127219179 (Map2k3)
Protein kinases [BR:prob01001]
 Serine/threonine kinases: STE group
  STE7 family
   127219179 (Map2k3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 127219179
NCBI-ProteinID: XP_051036442
Position
Unknown
AA seq 347 aa
MESPAASPPASLPQTKGKSKRKKDLRIACVSKPLVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADKFSPEFVD
FTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgccgcgagcccgccggccagcttgcctcagaccaaaggaaaatccaaa
aggaaaaaggatttacggatagcctgtgtgtccaagccactggtgcccaatcccacacca
ccccggaacctggactcccggaccttcatcacgatcggagacaggaactttgaggtggag
gctgatgacttggtgaccatctcagagctgggccgtggagcctatggggtggtggagaag
gtgcgacatgctcagagtggcactatcatggctgtaaagcgcatccgggccactgtgaac
tcacaagagcagaaacgcctgcttatggacctagacatcaacatgcgcacggttgactgc
ttctacactgtcaccttctatggtgccctcttcagagagggggatgtgtggatctgcatg
gagctcatggacacttccctggacaagttctaccggaaggtgctggacaagaacatgaca
attccggaggacatcctgggcgagattgcggtgtctatcgtgcgggccctggagcacctg
cacagcaagctgtctgtgatccacagagatgtgaagccttccaatgtcctcatcaacaag
gaggggcatgtgaagatgtgtgactttggcatcagtggctacctggtggactctgtggca
aagacaatggatgctggttgcaagccttacatggctcctgagaggatcaaccctgagctg
aatcagaagggctacaatgtcaagtctgacgtctggagcctcggcatcaccatgattgag
atggccattctgcgattcccttatgagtcttgggggacaccgtttcagcagctgaagcag
gtggtggaggaaccatccccacaactcccagctgacaagttctcccctgagtttgtggac
ttcactagccagtgcctaaggaagaaccctgcggagcgcatgagctacctggagctgatg
gaacatcctttcttcaccttgcacaaaactaagaagacagacattgctgcctttgtgaag
gagatcctgggagaggattcatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (42)   

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