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KEGG   Panthera pardus (leopard): 109251979
Entry
109251979         CDS       T06062                                 
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad00061  Fatty acid biosynthesis
ppad00620  Pyruvate metabolism
ppad00640  Propanoate metabolism
ppad01100  Metabolic pathways
ppad01212  Fatty acid metabolism
ppad04152  AMPK signaling pathway
ppad04910  Insulin signaling pathway
ppad04922  Glucagon signaling pathway
ppad04936  Alcoholic liver disease
Module
ppad_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    109251979 (ACACA)
   00640 Propanoate metabolism
    109251979 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    109251979 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    109251979 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    109251979 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    109251979 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109251979 (ACACA)
Enzymes [BR:ppad01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     109251979 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     109251979 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     109251979 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 109251979
NCBI-ProteinID: XP_019279561
Ensembl: ENSPPRG00000002505
UniProt: A0A9V1EDY5
Position
Unknown
AA seq 2346 aa
MDEPSPLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYQKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQA
FLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVI
GNDITYLIGSFGPQEDLLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSIVCDDFEGVFTVLHWLSYMPKNVHSLVPLLNSKDPID
RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDSLRECSQPVLVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSAAE
RKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
NT seq 7041 nt   +upstreamnt  +downstreamnt
atggatgaaccatcccccttggccaaacctctggagctgaaccagcactctcggttcata
attggttctgtatctgaagataactcagaggatgaaatcagcaacctggtgaagctggac
ctactggaggagaaggaaggctctctgtcaccagcttctgttggctcagatacgctctct
gatttggggatttccagcctacaggatggcttggccttgcacatgaggtccagcatgtct
ggcttgcatctagtaaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc
actgtagcttcaccagcagaatttgttacgcgttttggggggaataaagtgattgagaag
gttcttattgccaacaatggcatcgcagcagtgaaatgcatgcggtccatccgccgatgg
tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgttatggtcacacctgaa
gacctgaaagccaatgcagaatacattaagatggcagatcactatgtgccggtgccagga
ggaccaaacaacaacaactatgcaaacgtggaattaattcttgatattgctaaaaggatc
ccagtgcaagcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaa
cttcttttgaaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttg
ggggataagattgcatcttccatagtggctcaaactgctggtatcccaactcttccctgg
agtgggagtggtcttcgtgtggactggcaggaaaatgatttttcaaaacgtatcttaaat
gttccccaggaattatatcaaaaaggttatgtgaaggatgtggatgatgggctgaaggca
gcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaagga
atcagaaaagttaacaatgcagatgacttcccgaacctcttcagacaggttcaagctgaa
gtccctggatctcctatatttgtgatgagactagccaaacaatcccgtcatctggaggta
cagattttagcagatcagtatggcaatgctatctctctgtttggtcgtgactgctctgtg
cagcgcaggcatcagaagattattgaagaagcaccagctgctattgctactccagcagta
ttcgaacatatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgca
gggactgtcgaatacctctacagccaggatggaagcttctactttctggaactgaaccct
cggctacaggtagagcacccttgtacagagatggtggctgatgtcaacctccctgcagcg
caactccagattgccatggggatccctctgtatagaatcaaggatattcgtatgatgtat
ggagtatctccctggggtgatgctcccattgattttgaaaattctgctcatgttccttgc
ccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggttttaag
cccagctcaggaacagttcaggaactgaatttccgtagcaataagaatgtttggggttat
ttcagtgttgctgctgcagggggccttcacgaatttgctgattctcagtttggtcactgc
ttctcctggggagaaaacagagaggaagcaatttcaaacatggtggtggctttgaaggaa
ctatctattcggggtgactttcgaactacagttgaatacctcatcaaattgctggagact
gagagttttcagctgaatagaattgacactggctggctagacagactgatagcagaaaaa
gtacaggcagagcgacctgataccatgttgggagttgtgtgtggggctctccacgtggca
gatgtgagcctacggaatagcatctctaacttccttcattccttagaaaggggtcaagtt
cttcctgctcatacgcttctgaatacagtagatgttgaacttatctatgagggagtcaaa
tatgtacttaaggtgactcgacagtcccccaactcgtatgtggtgatcatgaacggctca
tgcgtagaagtagatgtgcatcggctgagtgatggagggctgctcctgtcctatgatggc
agcagttataccacatatatgaaggaggaagtggatagatatcgtatcacaattggcaat
aagacctgtgtgtttgagaaggaaaatgacccttcagtgatgcgctcaccttctgctggg
aagttaatccagtatattgtggaggatggaggccatgtgtttgctggccagtgctatgct
gagattgaggtgatgaagatggtaatgaccttaacagcagcagagtctggctgtatccat
tatgtcaaacggcctggagcagctcttgaccctggctgtgtgatagccaaaatgcagtta
gacaaccccagcaaggtccaacaggctgagcttcacacgggtagtctgccacggatccag
agcacagcactgagaggcgagaagctccatcgagtgttccattatgtcctggataatctg
gtcaacgtaatgaatggatactgccttccagatcctttttttagtagcagggtaaaagac
tgggtagagcggttgatgaagaccctcagagatccctccttgcctctcctagaattgcaa
gatatcatgaccagtgtctctggccgtattcccccaaatgtggagaagtctatcaagaag
gaaatggctcagtatgccagcaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacatcctagatagccatgcagctacattgaaccggaaatctgaacgggaagtt
ttcttcatgaacactcagagcattgtccagctggtacagaggtaccgaagtggcatccga
ggccacatgaaggctgttgtgatggatctgctacggcagtacctgcgagtagagacacag
ttccagaatggtcactatgacaaatgtgtgtttgcccttcgagaagagaacaagagtgac
atgaacactgtgctaaactatatcttctctcatgctcaagtcaccaagaagaatcttctg
gtcacaatgcttattgatcagttgtgtggtcgggaccctactctcactgatgagctgctg
aatattctcacagagctaactcaactcagtaagaccaccaatgccaaagtggcacttcga
gcacgccaggttcttattgcctcccatttgccgtcatatgagcttcgccataaccaagta
gagtctatcttcctttcagctattgacatgtatggacatcagttttgcattgagaacctg
cagaaactcatcttgtctgaaacatctatttttgatgtcctaccaaacttcttctatcac
agcaaccaggtagtgaggatggcagctctggaggtttatgttcgaagggcttacattgcc
tatgaacttaacagcgtccaacatcgccagcttaaggacaatacctgcgtggtggaattc
cagttcatgctgcccacatcgcatccaaacagagggaacatccccacgctaaacagaatg
tccttctcctccaacctcaaccactatggcatgactcacgtagctagtgtcagcgatgtg
ctgttggacaactcattcactccaccgtgtcagcggatgggcggaatggtctcttttcgg
acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgactcccca
ccccaaagccccacgttccctgaggcaggtcacacatctctgtatgatgaagacaaggtc
cccagggatgaaccaattcacattctgaatgtggctatcaagactgactgtgatattgag
gatgacagactggcagctatgttcagagagtttacccaacaaaataaagctaccctggtt
gagcatgggatacggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtc
aactatgaggtggatcagagatttcatagagaatttcctaaatttttcacgttccgagca
agggataagtttgaggaggatcgtatctatcgtcacctggagcctgctctagctttccag
ttagaactgaaccggatgagaaattttgaccttactgccattccatgtgctaatcataag
atgcacctgtatcttggggcagccaaggtggaagtgggcactgaagtgacagactatagg
ttctttgttcgtgcaatcatcagacattctgatctggtcaccaaggaagcttcttttgaa
tatctacaaaatgaaggggagcggctgctcctggaagccatggatgaattggaagttgct
tttaataatacaaatgttcgcactgactgcaaccacatcttcctcaactttgtgcccaca
gtcattatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatgga
agtcggctgtggaaattacgtgtcctccaggcagaactgaaaatcaacattcgcctgaca
ccaactggaaaagcaattcccatccgcctcttcctgacaaatgagtccggctattacttg
gacatcagcttgtacaaggaagtgactgactccaggacagcacagatcatgtttcaggca
tatggagacaaacagggaccattgcatggaatgttaatcaacactccatatgtcaccaaa
gacctacttcaatcaaagagattccaggcacaatccttggggacaacatacatatatgat
atcccagagatgtttcggcagtctctgatcaaactctgggagtctatgtccactcaagca
ttccttccatcaccccccctgccttctgacatgctgacatatactgagcttgtgttggat
gatcagggtcagctggtccacatgaacaggcttccaggaggaaatgagattggcatggta
gcttggaaaatgacccttaaaagtcctgaatatccagaaggccgagatatcattgttatt
ggcaatgacatcacatacctaattgggtcctttgggccccaggaggatttgctgtttctc
agagcttctgagcttgccagggcagagggtatcccacgcatctttgtagcagccaacagc
ggagcacgaattggactggcagaggaaattcgtcatatgtttcacgtggcctgggtagat
cctgaggatccttacaagggatacaaatacttatatctgacccctcaggattataagagg
gtcagtgctctcaactctgtccactgtgaacatgtagaagatgaaggagaatccaggtac
aagataactgatattattgggaaggaagagggacttggagcagagaaccttcgaggctct
ggaatgattgctggagaatcctcattggcctataatgagattatcaccatcagcttggtt
acatgccgggctattgggattggagcttaccttgtccggctgggacagagaaccatccag
gttgaaaattctcacttaattctgaccggagctggagctctcaacaaagtccttgggcgg
gaagtatacacctccaataaccagcttgggggcatccagatcatgcacaacaatggggtg
acccacagcatcgtttgtgatgactttgaaggggttttcactgtcctacactggctgtct
tacatgcctaagaatgtgcacagtttagtacctctcctgaactccaaggatcctatagat
agaatcatcgaatttgttcctacgaaggccccctatgatcctcgatggatgctagcaggc
cgtcctcacccaacccagaaaggtcagtggttgagtggattctttgactatggatctttc
tctgaaatcatgcaaccctgggcacagactgtggtggttggcagagccaggctaggagga
atacctgtaggagtagttgctgtagaaacccgaacagtggaactaagtatcccagccgac
cctgcaaacctggattctgaagccaagataatccagcaggctggccaggtttggtttcca
gattctgcgtttaagacctatcaggctatcaaggacttcaaccgcgaagggctgcctctg
atggtctttgccaactggagaggcttctccggtgggatgaaagatatgtacgaccaggtg
ctgaagtttggtgcttacatcgtggatagcttacgggagtgctcccagcctgtgctggtt
tacattcctcctcaagctgagctccggggtggctcctgggttgtgattgaccccaccatc
aacccccggcacatggagatgtatgctgaccgagaaagcaggggatcggttctggagcca
gaagggacagtagaaatcaaattccgcagaaaagatctggtgaaaaccatgcgtcgggtg
gacccagtctacattcgcttggctgaacgattgggcaccccagagctaagcgcagctgag
cggaaggagctggagaacaagttgaaggagcgggaggaattcctaattcccatttaccat
caggtagccgtgcagtttgctgacttgcacgacacaccaggacggatgcaggagaagggt
gttattaacgacatcctggattggaaaacatcccgtaccttcttctactggcggctgagg
cgtctcctgctggaggacctggtcaaaaagaaaatccacaatgccaacccagagctcact
gacggtcagatccaggccatgttaaggcgctggtttgtagaagtggaaggaaccgtgaag
gcctatgtttgggacaataacaaggatctagtggaatggctggagaaacagctgaccgag
gaagatggtgttcgctcagtaatagaggaaaacataaaatacatcagcagagactatgtc
ctcaagcagatccgcagcttggtacaggccaatcccgaggttgccatggattccatcgtc
catatgacccagcacatctcacccactcagcgagcagaagtcgtacggatcctctccacg
atggactccccttcaacatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (9)   
   KEGG MODULE (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (21)   
   UniProt (1)   
   RefSeq(pep) (20)   
DNA sequence (20)   
   RefSeq(nuc) (20)   
Protein domain (10)   
   Pfam (10)   
All databases (83)   

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