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KEGG   Panthera pardus (leopard): 109245742
Entry
109245742         CDS       T06062                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04010  MAPK signaling pathway
ppad04015  Rap1 signaling pathway
ppad04218  Cellular senescence
ppad04620  Toll-like receptor signaling pathway
ppad04664  Fc epsilon RI signaling pathway
ppad04668  TNF signaling pathway
ppad04714  Thermogenesis
ppad04750  Inflammatory mediator regulation of TRP channels
ppad04912  GnRH signaling pathway
ppad04935  Growth hormone synthesis, secretion and action
ppad04936  Alcoholic liver disease
ppad05014  Amyotrophic lateral sclerosis
ppad05022  Pathways of neurodegeneration - multiple diseases
ppad05132  Salmonella infection
ppad05135  Yersinia infection
ppad05145  Toxoplasmosis
ppad05161  Hepatitis B
ppad05169  Epstein-Barr virus infection
ppad05170  Human immunodeficiency virus 1 infection
ppad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ppad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    109245742 (MAP2K3)
   04668 TNF signaling pathway
    109245742 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109245742 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    109245742 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    109245742 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109245742 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    109245742 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109245742 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109245742 (MAP2K3)
   05161 Hepatitis B
    109245742 (MAP2K3)
   05169 Epstein-Barr virus infection
    109245742 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    109245742 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109245742 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    109245742 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    109245742 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109245742 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109245742 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppad01001]
    109245742 (MAP2K3)
Enzymes [BR:ppad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     109245742 (MAP2K3)
Protein kinases [BR:ppad01001]
 Serine/threonine kinases: STE group
  STE7 family
   109245742 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 109245742
NCBI-ProteinID: XP_019268767
Ensembl: ENSPPRG00000004291
UniProt: A0A9V1DWB5
Position
Unknown
AA seq 347 aa
MESPASSQPSSMPPTKGKSKRKKDLRISCMSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADSFSPEFVD
FTAQCLRKSPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctccagtcagccctccagcatgcccccgaccaaagggaaatccaag
aggaagaaggatttgcggatatcctgcatgtccaagccgcctgtacccaaccctacaccc
ccccggaacctggactctcggaccttcatcaccatcggagacaggaattttgaggtggag
gccgatgacctggtgaccatctcagagctgggccgtggagcctatggggtggtggagaag
gtgcggcatgcccagagtggcaccatcatggccgtgaagcggatccgggccactgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcgcacagtcgactgc
ttctacactgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaagtgctcgataaaaacatgacc
attccagaggacatcctgggggaaattgctgtgtctatcgtccgggcactggagcatctg
cacagcaagctgtccgtgatccacagagatgtgaagccgtccaatgtcctcatcaacaag
gagggtcatgtgaagatgtgcgacttcgggattagcggctatttggtggactctgtggcc
aagacgctggatgctggctgcaagccctacatggctcccgagagaatcaacccggagctg
aaccagaagggctacaacgtcaagtccgacgtctggagcctcggcatcaccatgatcgag
atggccattctacggtttccttatgagtcctgggggaccccgttccagcagctgaaacag
gttgtggaggagccatctccccagctcccagctgactcgttctctcccgagtttgtggac
ttcaccgcacagtgcctgaggaagagccccgcggagcgcatgagctacctggagctgatg
gagcaccctttcttcaccttgcacaaaaccaagaagacggacattgctgcctttgtgaag
gagatcctgggggaggactcgtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (44)   

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