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KEGG   Propithecus coquereli (Coquerel's sifaka): 105813836
Entry
105813836         CDS       T08746                                 
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq00061  Fatty acid biosynthesis
pcoq00620  Pyruvate metabolism
pcoq00640  Propanoate metabolism
pcoq01100  Metabolic pathways
pcoq01212  Fatty acid metabolism
pcoq04152  AMPK signaling pathway
pcoq04910  Insulin signaling pathway
pcoq04922  Glucagon signaling pathway
pcoq04936  Alcoholic liver disease
Module
pcoq_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    105813836 (ACACA)
   00640 Propanoate metabolism
    105813836 (ACACA)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    105813836 (ACACA)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    105813836 (ACACA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    105813836 (ACACA)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    105813836 (ACACA)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105813836 (ACACA)
Enzymes [BR:pcoq01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     105813836 (ACACA)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     105813836 (ACACA)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     105813836 (ACACA)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_lipoyl Biotin_carb_C ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 105813836
NCBI-ProteinID: XP_012504091
Ensembl: ENSPCOG00000018915
Position
Unknown
AA seq 2298 aa
MWWSTLMSILRASSFWRWISAQTVRIIRALRAHFKGIMDEPSPLAKPLELNQHSRFIIGS
VSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHIRSSMSGLH
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRK
VNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDTPVDFENSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHR
LSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVE
DGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYIKRPGAALDPGCVIAKMQLDNPSKVQQ
AELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNIMNGYCLPDPFFSSRVKDWVERLMKT
LRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSH
AATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDK
CVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQ
LSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSET
SIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSH
PNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRI
FDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMF
REFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDR
IYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIR
HSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKI
EESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEV
TDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQS
LIKLWESMSTQVFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKS
PEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAE
EIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGK
EEGIGAENLRGSGMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLIL
TGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLYWLSYMPKSVHS
SVPLLSSKDPIDRIIEFVPTKAPYDPRWMLAGRPHPTHKGQWLSGFFDYGSFSEIMQPWA
QTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQ
AIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDSLRECSQPVLVYIPPQAEL
RGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIRLA
ERLGTPELSLAERKDLENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDW
KTSRTFFYWRLRRLLLEELVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNK
DLVEWLEKQLTEEDGVRSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISP
TQRAEVIRILSTMDSPST
NT seq 6897 nt   +upstreamnt  +downstreamnt
atgtggtggtctactctgatgtcaatcttgagggctagttctttttggaggtggatatct
gctcaaacagtaagaattataagagctctgagagctcatttcaaaggaataatggatgaa
ccgtctcccttggccaaacctctggagctgaaccagcactcccgattcataattggttct
gtgtctgaagataactcagaggatgagatcagcaacttggtgaagctggacctgctagag
gagaaggagggttctctgtcacccgcttctgtcggctcagatacactctctgatttggga
atctctagcctgcaggatggcttggccttacacataaggtccagcatgtctggattgcac
ctagtaaagcaaggccgagaccgaaagaaaatcgactctcagagagatttcactgtggct
tctccagcagaatttgttacgcgctttgggggaaataaagtgattgagaaggttcttatt
gccaacaatggcattgcagcggtgaaatgcatgcggtctattcgtaggtggtcttatgaa
atgtttcgaaatgagcgtgcaatccgattcgttgtcatggtcacccctgaagaccttaaa
gccaatgcagaatacattaagatggcagatcactatgtgccagttcctggaggaccaaac
aacaacaactatgcaaatgtggaattaattcttgatattgctaaaaggatcccggtacaa
gcagtatgggctggctggggtcatgcttctgaaaatcccaagctcccggaacttctcttg
aaaaatggcattgcctttatgggtcctccaagccaggccatgtgggctttgggggataag
attgcatcttctatagtggctcaaactgctggtatcccaactcttccctggagcggtagt
ggtcttcgtgtggactggcaggaaaatgatttttcaaaacgtatcttaaatgttcctcag
gaactatatgaaaaaggttatgtgaaagatgtggacgatgggctgaaggcagcagaggaa
gtaggatatccagtaatgatcaaggcctcagaaggaggtggagggaagggaatcagaaaa
gtcaataatgcagatgacttccctaaccttttccgacaggttcaagctgaagtccctgga
tctcctatatttgtaatgagactagccaaacaatctcgtcatctggaggtgcagatccta
gcagatcaatatggcaatgctatctctctgtttggtcgtgactgctccgtacagcgcagg
catcaaaagattattgaagaggcacctgctgctattgctactccagcagtatttgaacat
atggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgctgggactgtg
gaatacctgtacagccaggatggcagcttctactttctagaattgaatcctcggctacag
gtggagcatccttgtacagagatggtggctgatgtcaatctccctgcagcacaactccag
attgccatggggatccctctatatagaatcaaagatatccgtatgatgtatggggtatcc
ccctggggcgacactcccgttgattttgaaaattctgctcatgttccttgcccaaggggc
catgttattgctgctcggatcactagtgaaaatccagatgagggttttaagcccagctca
ggaacagttcaggaactaaatttccgcagcaataagaacgtttggggttatttcagtgtt
gctgctgcagggggacttcatgaatttgctgattctcagttcggtcactgcttttcctgg
ggagaaaacagagaggaagcaatttcgggtcaagtccttcctgctcatacgcttctgaat
acagtagatgttgaacttatctatgagggagtgaaatacgtgcttaaggttactcgacag
tcccccaactcctatgtggtgatcatgaatggctcatgtgtggaagtagatgtacatcgg
ctgagtgacggaggactgcttttgtcctatgatggcagcagttacactacgtacatgaag
gaggaagtagatagatatcgcatcacgattggtaataaaacctgtgtgtttgagaaggaa
aatgacccatcggtgatgcgctcaccttctgctgggaagttaatccagtacattgtggag
gatggaggtcatgtgtttgctggccagtgctatgctgagattgaggtgatgaagatggta
atgactttaacagctgcagagtctggctgtatccattacatcaagcggcctggagcagct
cttgaccctggctgtgtaatagccaaaatgcagctggacaaccccagcaaggttcagcag
gctgagcttcacacgggtagtctgccacggatccagagcacggcacttagaggcgagaag
ctccatcgagtgttccactacgtcctggataatctggtcaacataatgaatggatactgc
cttccagatcctttctttagcagcagggtaaaagactgggtagagcggttgatgaagacc
ctcagagatccctctcttcctctcctagaattgcaagatatcatgaccagtgtctctggc
cgtatccctcccaatgtggagaagtctatcaagaaggaaatggctcagtatgctagcaac
atcacatcagtcctctgtcagtttccaagccaacagattgccaacatcctagatagccat
gcagctacattgaaccggaaatctgaacgggaagttttcttcatgaacactcagagcatt
gtccaactggttcagaggtaccgaagtggcatccgaggccacatgaaggccgtggtgatg
gatctgctccggcagtacctgcgagtagagacacaattccagaatggtcactatgacaaa
tgtgtgtttgcccttcgggaagagaacaagagtgacatgaacactgtactgaactacatc
ttctctcatgctcaagtcaccaagaagaatcttctggtcacaatgcttattgatcagttg
tgtggccgggaccctactctcactgatgagctactgaatatcctcactgagctaacccaa
ctcagtaagaccaccaatgctaaagtggcgcttcgagcacgccaggttcttattgcctcc
catttgccatcctatgagcttcgccataaccaagtcgagtctatcttcctatcagctatt
gacatgtacggacatcagttctgcattgagaacctacagaaactcatcctatctgaaaca
tctatttttgatgtcctaccaaacttcttctatcacagcaaccaggtagtgaggatggca
gctctggaggtgtatgttcgaagggcttatatcgcctatgaacttaacagtgtgcagcac
cgccagcttaaggacaacacctgtgtggtggaattccagttcatgctgcccacatctcat
ccaaacagagggaacatccccacgctaaacagaatgtccttctcctccaacctcaaccac
tatggcatgactcatgtagctagtgtcagcgatgtgctattggacaactcattcactcca
ccgtgtcagcgtatgggcggaatggtctcttttcggacttttgaggattttgtcaggatc
ttcgatgaagtgatgggctgcttctgtgattccccaccccagagccccacattccctgag
gcaggtcacacgtcgctgtatgatgaagataaggtccccagggatgaaccaattcacatt
ctgaatgtggctatcaagactgactgtgatattgaggatgacagattagcagctatgttc
agagagtttacccagcaaaacaaggctaccctggttgagcacgggatccgccgccttact
ttcctggttgcacaaaaggatttcagaaaacaggtcaactatgaggtggatcagagattc
catagagaattccctaaatttttcacattccgagcgagagataagtttgaggaggatcgt
atctatcgtcacctggagcctgctctggctttccagttagagctgaaccggatgagaaat
tttgacctcactgccattccgtgtgcgaatcacaagatgcacctgtatctcggggcagcc
aaagtggaagtgggcacagaagtgacagactacaggttctttgttcgtgctatcatcaga
cattccgatctggtcaccaaggaagcttcttttgaatatctacaaaatgaaggggagcga
ctccttctggaagccatggatgagttggaagttgcttttaacaatacaaatgtccgcact
gactgtaaccacatcttcctcaactttgtgcccacagtcatcatggacccatcaaagatt
gaagaatctgtgcggagcatggtaatgcgctatggaagtcggctgtggaaattacgcgtc
ctccaggcagaactgaaaatcaacattcgcctgacaccaactggaaaagcaattcctatc
cgcctcttcctgacaaacgagtctggctattacttggacatcagcctctacaaggaagtg
actgactccaggacagcccagatcatgtttcaggcatatggagacaaacagggaccactg
catggaatgttaatcaatactccatatgtgaccaaagacctgcttcaatcaaagaggttc
caggcacagtccttagggacaacatacatatatgatattccagagatgtttcggcagtcc
ctgatcaaactctgggagtctatgtccactcaagtattccttccctcacctcctctgcca
tctgacatactgacatataccgagctagtgttggacgatcaaggtcagctggtacacatg
aacaggcttccaggaggaaatgagattggcatggtagcttggaaaatgaccctgaaaagt
cctgaatatccagaaggccgagatatcattgttattggcaatgacatcacataccgaatt
gggtcctttgggcctcaagaggatttgttgtttctcagagcttcggaacttgccagggca
gagggtattccacgcatttatgtagcagccaacagtggagcaagaattggactggcagaa
gaaattcgtcatatgtttcatgtggcctgggtagatcctgaggatccttacaagggatac
aagtatttatatctgacccctcaagattataagagagtcagtgctctcaactctgtccat
tgtgagcacgtggaggatgaaggagaatccaggtacaagataacagatattattgggaaa
gaagagggcattggagcagagaaccttcgaggttctggaatgattgctggagaatcatca
ttggcctatgatgagatcatcaccatcagcctggtgacatgccgggccattgggattggg
gcttaccttgtccggctgggacagagaaccatccaggttgagaattctcacctaattctg
acaggagctggagctctcaacaaagtcctcgggcgggaggtgtacacctccaataaccag
cttggaggcatccagatcatgcacaataatggagtgacccactgcaccgtttgcgatgac
tttgaaggggttttcactgtcctgtactggctgtcctacatgcctaagagcgtgcacagt
tcagttcctcttctgagctccaaggatcccatagatagaatcatcgagtttgttcccaca
aaggccccatatgatcctcgatggatgctggcaggccgtcctcacccaacccataaaggt
cagtggttgagtggattttttgactatggctctttctcggagattatgcagccctgggca
cagacggtggtggttggtagggccaggctaggaggaatacctgtgggagtcgttgccgta
gaaacccgaacagtagaactaagtatcccagctgatcctgcaaacctggattctgaagcc
aagataatccagcaagctggccaggtttggttcccagactctgcatttaagacctaccag
gctatcaaggacttcaaccgtgaagggctgcctctgatggtctttgccaactggagaggc
ttctcgggtgggatgaaagatatgtatgaccaagtgctaaagtttggtgcctacatcgtg
gacagcttgagggagtgctcccagcctgtgttggtttacatccctccccaggccgagctg
cggggtggctcctgggttgtgattgaccccaccatcaacccccggcacatggagatgtat
gctgatcgagaaagcaggggatcagttctggagccagaagggacagtagaaatcaaattc
cgcagaaaggatctagtgaaaaccatgcgtcgggtggacccagtctacatccgcttggct
gagcgattgggcaccccagagctaagcctagctgagcggaaggatctggagaacaagttg
aaggagcgggaggaattcctaattcccatttaccatcaggtagctgtgcagtttgctgac
ttgcacgacacaccaggccggatgcaggagaagggtgttattaatgacatccttgattgg
aaaacatcccgtacgttcttctactggcggctaaggcgtctcctgctggaggagctggtc
aagaagaaaatccacaatgccaaccccgagctgaccgatggccagatccaggccatgtta
aggcgctggtttgtggaagtggaaggaacagtgaaggcctatgtttgggacaataataag
gatcttgtggaatggctggagaaacagctgacagaggaagatggtgttcgctcagtgata
gaggaaaacatcaagtgtatcagcagagactacgtcctcaagcagatccgcagcttggtc
caggccaatccagaggttgccatggattccatcgtccacatgacccagcacatctcaccc
actcagcgagcagaagtcatacggatcctctccacaatggattccccgtccacgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (9)   
   KEGG MODULE (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (44)   

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