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KEGG   Petaurus breviceps papuanus (sugar glider): 138149213
Entry
138149213         CDS       T10505                                 
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
pbrv  Petaurus breviceps papuanus (sugar glider)
Pathway
pbrv00562  Inositol phosphate metabolism
pbrv01100  Metabolic pathways
pbrv01521  EGFR tyrosine kinase inhibitor resistance
pbrv04012  ErbB signaling pathway
pbrv04014  Ras signaling pathway
pbrv04020  Calcium signaling pathway
pbrv04062  Chemokine signaling pathway
pbrv04064  NF-kappa B signaling pathway
pbrv04066  HIF-1 signaling pathway
pbrv04070  Phosphatidylinositol signaling system
pbrv04072  Phospholipase D signaling pathway
pbrv04360  Axon guidance
pbrv04370  VEGF signaling pathway
pbrv04380  Osteoclast differentiation
pbrv04611  Platelet activation
pbrv04613  Neutrophil extracellular trap formation
pbrv04625  C-type lectin receptor signaling pathway
pbrv04650  Natural killer cell mediated cytotoxicity
pbrv04662  B cell receptor signaling pathway
pbrv04664  Fc epsilon RI signaling pathway
pbrv04666  Fc gamma R-mediated phagocytosis
pbrv04670  Leukocyte transendothelial migration
pbrv04722  Neurotrophin signaling pathway
pbrv04750  Inflammatory mediator regulation of TRP channels
pbrv04919  Thyroid hormone signaling pathway
pbrv04933  AGE-RAGE signaling pathway in diabetic complications
pbrv04935  Growth hormone synthesis, secretion and action
pbrv05167  Kaposi sarcoma-associated herpesvirus infection
pbrv05169  Epstein-Barr virus infection
pbrv05170  Human immunodeficiency virus 1 infection
pbrv05171  Coronavirus disease - COVID-19
pbrv05200  Pathways in cancer
pbrv05205  Proteoglycans in cancer
pbrv05206  MicroRNAs in cancer
pbrv05214  Glioma
pbrv05223  Non-small cell lung cancer
pbrv05225  Hepatocellular carcinoma
Module
pbrv_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
Enzymes [BR:pbrv01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     138149213 (PLCG2)
Membrane trafficking [BR:pbrv04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    138149213 (PLCG2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    138149213 (PLCG2)
SSDB
Other DBs
NCBI-GeneID: 138149213
NCBI-ProteinID: XP_068928339
Position
Unknown
AA seq 1264 aa
MTTKINLDTLPEYEKSQIKRTLELGTVMTLFSLKKSNPERRTVQVITETRQVAWSKTADK
IEGFLDLMEIKEIRPGKNSKDFERGKASRQKEDCCFTIFYGTQFVLNTLSLATDSKEDAT
KWLCGLTILHQEAQSASTPAIIESWLRKQIYSVDQTRRNSISFRELKTILPLVNFKVSSA
KFLKDKFLEIGAYKDELSFEQFHLFYKKMMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQESWAQDLSKVRERMTKFIDDTMRETAEPFLFIDEFLTYLFSKENS
IWDDKYDTVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTESYVRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVSSQFPVILSIEEHCCVEQQRHMARV
FKEVFGDLLLTKPTEASADQLPSPAQLKEKIVIKHKKLGPRGDVDINIEDKKEEKKQQGE
LYMWDTIDQKWYRHYCAIADEKLSFSDVIEQNVEEDSVKDISQTDLHFGEKWFHKKMEKR
TSAEKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTPEGGTMKYY
LTDNLMFNSIYDLIQHYREAHLRCAEFELRLTDPVPNPNPHESKAWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGGDAYAITFRAKGKVKHCRINKDGHHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNTERDINSLYDVRMYVDPSEINPSTPQRTVKALYDYK
AKRGDELSFCRGALIHNVSKEPGGWWKGDYGGRIQQYFPSNYVEDISTADFEELEKQIIE
DNPLGSLCRGILDLNTYNVVKVPHGKNQKPFVFILEPKKPNDPPIEFATDKVEELFEWYQ
SIREITWKNATVETNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVET
KADSIVRQKPIDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTGDKYM
QLNHALFALNGRTGYVLQPESMRNENYDPTPPESQRKILMTLTVKVLGARHLPKLGRSIA
CPFIEVEICGTEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEEDM
FSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCR
QLRRRQEELNNQLFLYDTHQNLRNANRDALVNEFNVNENQLQLYQEKCNRRLREKRVSNS
KFYS
NT seq 3795 nt   +upstreamnt  +downstreamnt
atgaccaccaagatcaacttagacacacttcctgaatatgagaaaagtcagatcaagcgg
actctggaactaggaactgtcatgaccctgtttagcctcaagaagtctaaccctgagagg
aggacagtccaggtcatcacagagaccaggcaggtggcctggagcaagacggctgacaag
atcgaaggtttcttggacttaatggagataaaggaaatccgcccagggaaaaactcaaag
gactttgaacgtgggaaagccagtcgccagaaagaagattgctgctttaccatattttat
ggcacccagtttgtcctcaacaccctgagtttagcaacggattccaaggaagatgctact
aaatggctttgtggcttgacaattttgcaccaagaagcccagagtgcttcaacaccagct
attattgagagctggctaagaaagcaaatttattctgtagatcaaactcggagaaatagt
atcagcttcagagaactgaagaccattcttcctttagtaaacttcaaagttagcagcgcc
aagttcctgaaggacaaattcctggaaataggtgcctacaaggatgaactcagctttgaa
cagtttcacttattctacaaaaagatgatgtttgagcaacagaaatcaattcttgatgag
ttcaaaaaagattcgtctgtgtttattctgggaaatacagatcggccagatgcatctgcc
gttcatctgcatgacttccagaggtttctgctgcatgaacagcaggaaagctgggcacaa
gatctaagtaaagtaagagagcggatgacaaaatttatagatgacactatgagagaaaca
gctgagccgttcctgtttatcgatgagttccttacgtacctgttttcaaaagaaaacagc
atttgggatgataaatatgatacagttgacatgcaagacatgaataaccccttgtctcat
tattggatttcttcatctcataacacgtacctcaccggggaccagcttcgaagtgaatct
tctactgaatcctatgttcgatgtcttcgaatgggttgccggtgtatagagttggattgc
tgggatgggcctgatgggaagccgatcatctatcatggctggactcggacgacgaaaatc
aagtttgatgatgtggtgcaggccatcagagaccatgcttttgtctcctcacagttccct
gtgatcctctccattgaagagcactgctgtgtagaacagcagcgccatatggccagggtg
tttaaggaagtgtttggggacctcctccttacaaagcccactgaagccagtgccgaccag
ctgccatcccctgcccagctgaaagaaaaaattgtcatcaagcacaagaagctgggtccc
agaggagatgtggacatcaacattgaagacaagaaggaggaaaaaaaacagcaaggggaa
ttgtacatgtgggacaccattgatcagaagtggtatcgtcactattgtgccatagccgac
gagaagctgtccttcagtgatgttatagagcagaatgtggaggaggattcagtaaaggat
atatcacagactgacttgcattttggtgagaagtggtttcataagaagatggagaaaagg
acaagtgctgagaaactgctgcaagaatactgtgctgaaactgggggaaaggatggaacc
ttcttagtccgtgaaagtgagactttccctaatgactacacgctgtccttctggagatca
ggcagagtccagcactgtcgaatacggtcaactcctgagggagggaccatgaagtattat
ttgactgacaacctcatgttcaacagcatctatgacttgattcaacactaccgagaagcc
cacctgagatgtgcagaatttgagcttcgtctgacagacccagtacccaaccccaatcct
cacgaatcaaaagcttggtactatgatagcctgagcagaggagaagctgaagacatgttg
atgagaattccccgagatggagccttcctgattaggaaaagagaagggggagatgcatat
gccattactttcagagccaaaggaaaagtgaaacattgcaggattaacaaagatgggcac
cactttgtgctggggacgtctgcttactttgaaagtttggtggagttggtcagctattat
gaaaagcatgcactctacaggaaaatgagactgcgctatcctgtaactccagagctgctg
gagcgttacaacaccgaaagggacataaattcactctatgatgtcaggatgtatgtggat
cccagtgaaattaacccctcaacgccccagagaaccgtgaaggctttatatgactacaaa
gccaagcgtggggatgagctcagcttctgtcggggggccctcatccacaatgtctccaag
gagcctggtggctggtggaagggtgattatggaggaaggattcagcaatattttccatct
aattatgtggaggacatatcaacagctgattttgaagagctggaaaaacagattattgaa
gataaccctttaggatctctgtgcagaggaatcttggatcttaatacctataatgttgtg
aaagtaccacatggaaaaaaccagaagccatttgtcttcatcctggaacccaagaaaccc
aatgatcctcccatagagtttgcaactgacaaagtggaagagctctttgagtggtaccag
agcatcagggaaatcacctggaagaatgcaacagtggagaccaacatgaagtattgggag
aagaatcaatcaattgccatagaactatccgacttagttgtctactgtaagccaacgagt
aaaaccaaggataatttagaaaatcctgatttcagagaaattcgctctttcgtggagacc
aaggctgacagcatcgttaggcagaagccaattgatctcttgaagtacaatcaaaaggga
ctgactcgggtctacccaaaaggccaaagggtggactcatcaaattatgatccttttcga
ctttggctttgtggctctcagatggttgctctgaatttccagacaggagataaatatatg
cagctgaatcatgctttatttgcacttaatggccggactggctatgtcctgcagcccgaa
agcatgaggaatgaaaactatgatccaacacccccggaatcacaaaggaagatcctgatg
accctgacggtcaaggtcctgggggctcgccatctacccaagctcggcagaagcattgcc
tgtccatttatagaggtggaaatttgtggaactgagtatgataataacaaattcaagaca
actgtagtgaatgataatggcctgagtccagtctgggcgtctactcaggaaaaagtgaca
tttgaaatttatgacccaaatcttgcatttctacgctttgttgtttatgaggaggatatg
ttcagcgaccccaactttctggcacatgccacttatcccattaaaggaatcaaatcaggg
tttagatcagttcctcttaaaaatggttacagtgaagatattgaactggcctcccttctg
gttttctgtgagatgcgtcctgtcttggaaagtgaagaagaactctattcttcctgtcgc
cagcttcgaaggcggcaagaggagctgaataaccaactcttcctgtatgacactcatcag
aatttacgtaatgctaacagagatgccctggtgaatgaattcaatgtcaatgaaaatcag
ttgcagctttatcaggaaaagtgcaaccggagattaagggagaagagggtcagtaacagc
aaattctactcctag

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