[go: up one dir, main page]
More Web Proxy on the site http://driver.im/
KEGG   Prionailurus bengalensis (leopard cat): 122494519
Entry
122494519         CDS       T07574                                 
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg00562  Inositol phosphate metabolism
pbg01100  Metabolic pathways
pbg01521  EGFR tyrosine kinase inhibitor resistance
pbg04012  ErbB signaling pathway
pbg04014  Ras signaling pathway
pbg04020  Calcium signaling pathway
pbg04062  Chemokine signaling pathway
pbg04064  NF-kappa B signaling pathway
pbg04066  HIF-1 signaling pathway
pbg04070  Phosphatidylinositol signaling system
pbg04072  Phospholipase D signaling pathway
pbg04360  Axon guidance
pbg04370  VEGF signaling pathway
pbg04380  Osteoclast differentiation
pbg04611  Platelet activation
pbg04613  Neutrophil extracellular trap formation
pbg04625  C-type lectin receptor signaling pathway
pbg04650  Natural killer cell mediated cytotoxicity
pbg04662  B cell receptor signaling pathway
pbg04664  Fc epsilon RI signaling pathway
pbg04666  Fc gamma R-mediated phagocytosis
pbg04670  Leukocyte transendothelial migration
pbg04722  Neurotrophin signaling pathway
pbg04750  Inflammatory mediator regulation of TRP channels
pbg04919  Thyroid hormone signaling pathway
pbg04933  AGE-RAGE signaling pathway in diabetic complications
pbg04935  Growth hormone synthesis, secretion and action
pbg05167  Kaposi sarcoma-associated herpesvirus infection
pbg05169  Epstein-Barr virus infection
pbg05170  Human immunodeficiency virus 1 infection
pbg05171  Coronavirus disease - COVID-19
pbg05200  Pathways in cancer
pbg05205  Proteoglycans in cancer
pbg05206  MicroRNAs in cancer
pbg05214  Glioma
pbg05223  Non-small cell lung cancer
pbg05225  Hepatocellular carcinoma
Module
pbg_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    122494519 (PLCG2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    122494519 (PLCG2)
   04064 NF-kappa B signaling pathway
    122494519 (PLCG2)
   04066 HIF-1 signaling pathway
    122494519 (PLCG2)
   04070 Phosphatidylinositol signaling system
    122494519 (PLCG2)
   04072 Phospholipase D signaling pathway
    122494519 (PLCG2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122494519 (PLCG2)
   04613 Neutrophil extracellular trap formation
    122494519 (PLCG2)
   04650 Natural killer cell mediated cytotoxicity
    122494519 (PLCG2)
   04662 B cell receptor signaling pathway
    122494519 (PLCG2)
   04664 Fc epsilon RI signaling pathway
    122494519 (PLCG2)
   04666 Fc gamma R-mediated phagocytosis
    122494519 (PLCG2)
   04670 Leukocyte transendothelial migration
    122494519 (PLCG2)
   04062 Chemokine signaling pathway
    122494519 (PLCG2)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    122494519 (PLCG2)
   04919 Thyroid hormone signaling pathway
    122494519 (PLCG2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    122494519 (PLCG2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122494519 (PLCG2)
  09158 Development and regeneration
   04360 Axon guidance
    122494519 (PLCG2)
   04380 Osteoclast differentiation
    122494519 (PLCG2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122494519 (PLCG2)
   05206 MicroRNAs in cancer
    122494519 (PLCG2)
   05205 Proteoglycans in cancer
    122494519 (PLCG2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    122494519 (PLCG2)
   05214 Glioma
    122494519 (PLCG2)
   05223 Non-small cell lung cancer
    122494519 (PLCG2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122494519 (PLCG2)
   05171 Coronavirus disease - COVID-19
    122494519 (PLCG2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122494519 (PLCG2)
   05169 Epstein-Barr virus infection
    122494519 (PLCG2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    122494519 (PLCG2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122494519 (PLCG2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pbg04131]
    122494519 (PLCG2)
Enzymes [BR:pbg01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     122494519 (PLCG2)
Membrane trafficking [BR:pbg04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    122494519 (PLCG2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    122494519 (PLCG2)
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 SH3_1 PH SH3_9 PH_12 EF-hand_PLCG1 SH2_1 PH_14 SH3_2 GDPD EF-hand_like
Other DBs
NCBI-GeneID: 122494519
NCBI-ProteinID: XP_043455689
Position
E2:55665313..55826064
AA seq 1265 aa
MTAMVNMDTLPEYEKSQIKRTLELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAARQKEDCCFTILYGTQFVLSTLSLAADSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVNSA
KFLKDKFVEIGAHKDELSFEQFHVFYKNLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLLHEQQEVWAQDLNKVRERMTKFIDDTLRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDIQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARV
FKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQDIPPTELHFGEEWFHKKVEKR
TNAEKLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWRSGRVQHCRIRSVMEGGTMKYF
LTDNIMFTSIYDLIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYGGLSRGEAEDML
MRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRNDELSFCRGALIHNVSKEPWGWWKGDYGTRIQQYFPSNYVEDISTVDVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKMDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSVVRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
MQMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMQPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SRFYS
NT seq 3798 nt   +upstreamnt  +downstreamnt
atgaccgccatggtcaacatggacacccttcctgaatatgagaagagtcagatcaagaga
accctggagctgggcacggtgatgaccgtgttcagctttcgcaagtctacccccgagcgg
aggactgtccaggtgatcatggagacgcggcaggtggcctggagcaagacggctgacaag
attgaaggcttcttggatatcatggaaatcaaggaaatccgccccgggaagaactccaag
gattttgagcgtgcgaaggcagcccgccagaaggaagactgctgtttcaccatcttgtac
ggcacccagttcgtcctgagcaccctcagtttggcagctgattctaaagaagacgcgact
aagtggctctctggcttgaaaatcttacaccaggaagcgatgagtgcgtctacgcccacc
attattgagagttggctgagaaagcagatttattcagtggatcaaaccagaagaaacagc
atcagcctccgagagctgaagaccatcttgcccctggtcaacttcaaagtgaacagtgcc
aagttcctcaaagataagtttgtggaaatcggcgctcacaaagatgaactcagctttgag
cagttccacgttttctataaaaatcttatgtttgagcagcaaaagtcgattcttgatgaa
ttcaaaaaagattcttccgtgttcatcttgggcaacaccgaccggccggatgcctccgct
gtttacctgcacgacttccagcggtttctcctacacgaacagcaggaggtttgggctcag
gatctgaacaaagtccgcgagcggatgacaaagtttatcgatgacaccctgagggagacc
gccgagcccttcttgtttgttgatgagttcctcacgtacctgttttcgcgggagaacagc
atctgggacgagaaatacgacgtcgtggacatacaggacatgaacaaccccttgtcccat
tactggatctcctcctcacataacacgtacctcaccggtgaccagctgcggagtgagtcg
tccacggaggcatacatccgctgcctgcgcatgggctgtcgctgcatcgagctggactgc
tgggacgggcccgatgggaagcccatcatctaccacggctggacgcggaccaccaagatc
aagtttgatgacgttgtgcaggccatcaaagaccatgcctttgtcacctcaagcttcccg
gtgatcctgtccatcgaagagcactgctgtgtggagcagcagcgccacatggccagggtg
ttcaaggaggtgtttggcgacctgctgttgacgaagcccacggaggccagtgctgaccag
ctgccctcgcccagccagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggcgatgtggatgtcaacgtggaagataagaaagatgagcacaagcaacagggtgaa
ctgtacatgtgggattccattgaccagaaatggacccggcactactgtgccatcgctgat
gccaagctgtcgttcagcgatgacattgagcagactgcagaggaagagctgccccaggat
ataccccccacggagctgcattttggggaggagtggttccacaagaaggtggagaagaga
acaaatgccgagaagctgctgcaggaatactgtgccgagacggggggcaaagatgggacc
ttcttggtgcgggagagcaagaccttccccaacgactacaccctgtccttctggcggtcc
ggccgggtccagcactgccggatccgctccgtcatggagggcgggaccatgaagtacttc
ctgactgacaacatcatgttcaccagcatctatgacctcatccagcactaccgtgagacg
cacctgcgctgtgccgagttcgagctccgactcaccgaccccgtgcccaaccccaacccc
cacgagtcaaagccgtggtactatggtggcctgagccgcggggaagcagaggacatgctg
atgagagtgccccgggacggggccttcctgatccggaggcgggagggtaccgactcctac
gccatcaccttcagggccaggggcaaagtaaagcattgccgcatccatcgggacggccgg
cactttgtgctggggacctctgcctacttcgagagcctcgtcgagctggtcagttactac
gagaagcacgcgctgtaccggaagatgcggctgcgctatcctgtgacgcctgagctgctg
gagcgctacaatatggaacgagatatcaactccctctatgacgtcagcaggatgtatgtg
gatcccagtgaaatcaacccgtccatgcctcagaggaccgtcaaagctctgtatgactac
aaagccaagcgaaacgatgagctgagcttctgccgtggggccctcattcacaacgtctcc
aaggagccctggggctggtggaaaggagactatgggaccaggatccagcaatacttccca
tccaactacgttgaggacatttcaacggtcgatgtggaagaactggaaaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatactggatctcaacacctataacgtc
gtgaaagccccgcaggggaaaaaccagaaggcgttcgtgttcatcctggagccgaagaag
caaggcgaccctccggtggagtttgccacagacagggtcgaggagctctttgagtggttt
cagagcatccgggagatcacctggaagatggacaccaaggagaacaacatgaagtactgg
gagaagaaccagtccatcgccatcgagctctccgacctggtagtctactgcaagccgacc
agcaagaccaaggacaatttagaaaaccccgacttccgagaaatccgctccttcgtggag
acgaaggctgacagtgtcgtcagacagaaacccgtcgacctcctcaagtacaatcagaag
ggcctgacccgtgtttacccgaagggacagagggtggactcctccaactacgaccccttt
cgcctctggctgtgtggctcccagatggtggcactcaatttccagactccagacaagtac
atgcagatgaatcaagccttgttctcactcaacgggcggacaggctacgtcctgcagccc
gagagcatgaggacggagaagtacgaccccatgccgcccgaatcccagcggaagattctg
atgactctgaccgtcaaggttctcggggctcgccatctccccaaacttggccgaagcatc
gcatgtccctttgtggaggtggaaatctgtggggctgaatatgacaacaacaagtttaag
accacagttgtgaatgacaatggcctgagccctgtttgggctccgacacaggagaaggtg
acctttgaaatttatgacccaaacctcgcgtttctgcgctttgtggtctacgaggaagac
atgttcagtgatcctaacttcctcgctcatgccacttaccccatcaaaggaatcaaatca
ggattcagatctgttcctctgaagaacgggtacagtgaagatatcgagctggcttccctc
ctggtgttctgtgagatgcagccagtcctggagagtgaagaggaactctactcctcctgc
cgccagctgcgaaggcggcaggaagagctgaacaaccagctgttcctgtacgacacacac
cagaacctgcgcaatgccaaccgggatgccctcgtgaaagagttcaacgtcaacgagaac
cagctccagctgtaccaggagaagtgcaaccggaggttaagagagaagagagttagcaac
agtaggttttactcatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (38)   
   KEGG PATHWAY (37)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (15)   
   Pfam (15)   
All databases (74)   

Download RDF
DBGET integrated database retrieval system