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KEGG   Panthera tigris altaica (Amur tiger): 102961382
Entry
102961382         CDS       T02988                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase 3 beta
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg01521  EGFR tyrosine kinase inhibitor resistance
ptg04012  ErbB signaling pathway
ptg04062  Chemokine signaling pathway
ptg04110  Cell cycle
ptg04150  mTOR signaling pathway
ptg04151  PI3K-Akt signaling pathway
ptg04310  Wnt signaling pathway
ptg04340  Hedgehog signaling pathway
ptg04360  Axon guidance
ptg04390  Hippo signaling pathway
ptg04510  Focal adhesion
ptg04550  Signaling pathways regulating pluripotency of stem cells
ptg04657  IL-17 signaling pathway
ptg04660  T cell receptor signaling pathway
ptg04662  B cell receptor signaling pathway
ptg04722  Neurotrophin signaling pathway
ptg04728  Dopaminergic synapse
ptg04910  Insulin signaling pathway
ptg04916  Melanogenesis
ptg04917  Prolactin signaling pathway
ptg04919  Thyroid hormone signaling pathway
ptg04931  Insulin resistance
ptg04932  Non-alcoholic fatty liver disease
ptg04934  Cushing syndrome
ptg04935  Growth hormone synthesis, secretion and action
ptg04936  Alcoholic liver disease
ptg05010  Alzheimer disease
ptg05020  Prion disease
ptg05022  Pathways of neurodegeneration - multiple diseases
ptg05135  Yersinia infection
ptg05160  Hepatitis C
ptg05162  Measles
ptg05163  Human cytomegalovirus infection
ptg05165  Human papillomavirus infection
ptg05167  Kaposi sarcoma-associated herpesvirus infection
ptg05200  Pathways in cancer
ptg05210  Colorectal cancer
ptg05213  Endometrial cancer
ptg05215  Prostate cancer
ptg05217  Basal cell carcinoma
ptg05224  Breast cancer
ptg05225  Hepatocellular carcinoma
ptg05226  Gastric cancer
ptg05415  Diabetic cardiomyopathy
ptg05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    102961382 (GSK3B)
   04390 Hippo signaling pathway
    102961382 (GSK3B)
   04151 PI3K-Akt signaling pathway
    102961382 (GSK3B)
   04150 mTOR signaling pathway
    102961382 (GSK3B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102961382 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    102961382 (GSK3B)
   04657 IL-17 signaling pathway
    102961382 (GSK3B)
   04662 B cell receptor signaling pathway
    102961382 (GSK3B)
   04062 Chemokine signaling pathway
    102961382 (GSK3B)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    102961382 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    102961382 (GSK3B)
   04919 Thyroid hormone signaling pathway
    102961382 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    102961382 (GSK3B)
   04722 Neurotrophin signaling pathway
    102961382 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    102961382 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102961382 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102961382 (GSK3B)
   05225 Hepatocellular carcinoma
    102961382 (GSK3B)
   05226 Gastric cancer
    102961382 (GSK3B)
   05217 Basal cell carcinoma
    102961382 (GSK3B)
   05215 Prostate cancer
    102961382 (GSK3B)
   05213 Endometrial cancer
    102961382 (GSK3B)
   05224 Breast cancer
    102961382 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    102961382 (GSK3B)
   05162 Measles
    102961382 (GSK3B)
   05163 Human cytomegalovirus infection
    102961382 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102961382 (GSK3B)
   05165 Human papillomavirus infection
    102961382 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102961382 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102961382 (GSK3B)
   05020 Prion disease
    102961382 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    102961382 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102961382 (GSK3B)
   05415 Diabetic cardiomyopathy
    102961382 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102961382 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    102961382 (GSK3B)
   04931 Insulin resistance
    102961382 (GSK3B)
   04934 Cushing syndrome
    102961382 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102961382 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptg01001]
    102961382 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ptg03036]
    102961382 (GSK3B)
Enzymes [BR:ptg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     102961382 (GSK3B)
Protein kinases [BR:ptg01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   102961382 (GSK3B)
Chromosome and associated proteins [BR:ptg03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    102961382 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 102961382
NCBI-ProteinID: XP_007098408
UniProt: A0A8C9KH46
Position
Un
AA seq 420 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQTNSAASASASNST
NT seq 1263 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaagatggcagcaaggtaaccacagtg
gtggcaactcctgggcagggtcccgataggccacaagaagtcagctatacagacactaaa
gtgattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggttgccatcaagaaagtattgcaagacaagagatttaagaaccgagagctccaaatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactcaagtggt
gagaagaaagatgaagtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatctatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatatgccatcgg
gatattaaaccacagaacctcttgttggatcctgatacagctgtcttaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagacgta
tggtctgcaggttgtgtgttggctgagctgttgctaggacaaccaatatttccaggggac
agtggtgtggatcagttggtggaaataatcaaggtcctggggacaccaacaagggagcaa
attagagaaatgaacccaaactacacagaattcaaattccctcaaattaaggcacatcct
tggactaaggtcttccgaccccggactccaccggaggcaattgcactgtgtagccgtctg
ctggagtatacaccaactgcccgattgacaccactggaagcttgtgcacattcatttttt
gatgaactaagggacccaaatgtcaaactaccaaatgggcgagacacacctgcactcttc
aacttcaccactcaagaactgtcaagtaatccacctctagctaccattcttattcctcct
catgctcggattcaagcagctgcttcaacccctacaaatgccacagcagcctcagatgct
aatgctggagaccgtggacagaccaacagcgctgcttctgcatcagcttccaactccacc
tga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (6)   
   Pfam (6)   
All databases (18)   

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