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KEGG   Piliocolobus tephrosceles (Ugandan red Colobus): 111552288
Entry
111552288         CDS       T07491                                 
Symbol
GCK
Name
(RefSeq) hexokinase-4 isoform X1
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
pteh  Piliocolobus tephrosceles (Ugandan red Colobus)
Pathway
pteh00010  Glycolysis / Gluconeogenesis
pteh00052  Galactose metabolism
pteh00500  Starch and sucrose metabolism
pteh00520  Amino sugar and nucleotide sugar metabolism
pteh00524  Neomycin, kanamycin and gentamicin biosynthesis
pteh01100  Metabolic pathways
pteh01200  Carbon metabolism
pteh01250  Biosynthesis of nucleotide sugars
pteh04910  Insulin signaling pathway
pteh04911  Insulin secretion
pteh04917  Prolactin signaling pathway
pteh04922  Glucagon signaling pathway
pteh04930  Type II diabetes mellitus
pteh04950  Maturity onset diabetes of the young
pteh05230  Central carbon metabolism in cancer
Module
pteh_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
pteh_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:pteh00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    111552288 (GCK)
   00052 Galactose metabolism
    111552288 (GCK)
   00500 Starch and sucrose metabolism
    111552288 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    111552288 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    111552288 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    111552288 (GCK)
   04922 Glucagon signaling pathway
    111552288 (GCK)
   04917 Prolactin signaling pathway
    111552288 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    111552288 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    111552288 (GCK)
   04950 Maturity onset diabetes of the young
    111552288 (GCK)
Enzymes [BR:pteh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     111552288 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 111552288
NCBI-ProteinID: XP_023082191
Ensembl: ENSPTEG00000003496
Position
8:complement(32673313..32719886)
AA seq 466 aa
MAMDAMRSQAQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMG
ELVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRP
SATDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDIMRITVGVDGSVYKLHPSF
KERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGH
NT seq 1401 nt   +upstreamnt  +downstreamnt
atggcgatggatgccatgaggagccaggcccagacagccttgactctggtagagcagatc
ctggcggagttccagctgcaggaggaggacctgaagaaggtgatgagacggatgcagaag
gagatggaccgtggcctgaggttggagacccatgaagaggccagtgtgaagatgctgccc
acctacgtgcgctccaccccagaaggctcagaagtcggggacttcctctccctggacctg
ggtggcaccaacttcagggtgatgctggtgaaggtgggagaaggtgaggaggggcagtgg
agtgtgaagaccaaacaccagatgtactccatccccgaggacgccatgaccggcactgct
gagatgctcttcgactacatctccgagtgcatctccgacttcctggacaagcatcagatg
aagcacaagaagctgcccctgggcttcaccttctcctttcctgtgaggcatgaagacatc
gataagggcatccttctcaactggaccaagggcttcaaggcctcaggagcagaagggaac
aatgtcgtggggcttctgcgagacgccatcaaacggagaggggactttgaaatggatgtg
gtggcaatggtgaatgacacagtggccacgatgatctcctgctactacgaagaccatcag
tgcgaggtcggcatgattgtgggcacaggctgcaacgcctgctacatggaggagatgcag
aatgtggagctggtggagggggacgagggccgcatgtgcgtcaacaccgaatggggcgcc
ttcggggactcgggcgagctggacgagttcctgctggagtatgaccgcctggtggacgag
agctctgcaaaccccggtcagcagctgtatgagaagctcatcggtggcaagtacatgggc
gagctggtgcggctcgtgctgctcaggctcgtggacgaaaacctgctcttccacggggag
gcctccgagcagctgcgcacacgcggagccttcgagacgcgcttcgtgtcgcaggtggag
agcgacacgggcgaccgcaagcagatctacaacatcctgagcacgctggggctacgaccc
tcggccactgactgcgacatcgtgcgccgcgcctgcgagagcgtgtctacacgtgctgca
cacatgtgctcggcagggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgag
gacataatgcgcatcactgtgggcgtggatggctccgtgtacaagctgcatcccagcttc
aaggagcggttccacgctagcgtgcgcaggctgacgcccagctgcgagatcaccttcatt
gagtcggaggagggcagtggccggggcgcggccctggtctcggcggtggcctgtaagaag
gcctgcatgctgggccactga

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