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KEGG   VARIANT: 8324v1
Entry
8324v1                      Variant                                
Name
FZD7 overexpression
Gene
FZD7  frizzled class receptor 7 [KO:K02432]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
overexpression
Network
nt06215  WNT signaling (cancer)
nt06263  Hepatocellular carcinoma
nt06270  Breast cancer
Disease
H00031  Breast cancer
H00048  Hepatocellular carcinoma
Reference
  Authors
King TD, Suto MJ, Li Y
  Title
The Wnt/beta-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer.
  Journal
J Cell Biochem 113:13-8 (2012)
DOI:10.1002/jcb.23350
Reference
  Authors
Merle P, Kim M, Herrmann M, Gupte A, Lefrancois L, Califano S, Trepo C, Tanaka S, Vitvitski L, de la Monte S, Wands JR
  Title
Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma.
  Journal
J Hepatol 43:854-62 (2005)
DOI:10.1016/j.jhep.2005.05.018
Reference
  Authors
Minguez B, Tovar V, Chiang D, Villanueva A, Llovet JM
  Title
Pathogenesis of hepatocellular carcinoma and molecular therapies.
  Journal
Curr Opin Gastroenterol 25:186-94 (2009)
DOI:10.1097/MOG.0b013e32832962a1

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