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KEGG   Homo sapiens (human): 337876
Entry
337876            CDS       T01001                                 
Symbol
CHSY3, CHSY2, CSS3
Name
(RefSeq) chondroitin sulfate synthase 3
  KO
K13499  chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
hsa01100  Metabolic pathways
Module
hsa_M00058  Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
Network
nt06029  Glycosaminoglycan biosynthesis
  Element
N01580  Chondroitin sulfate biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    337876 (CHSY3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    337876 (CHSY3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.175  glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase
     337876 (CHSY3)
    2.4.1.226  N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase
     337876 (CHSY3)
Glycosyltransferases [BR:hsa01003]
 Glycan extension
  O-Glycan
   337876 (CHSY3)
SSDB
Motif
Pfam: CHGN Fringe Glyco_transf_7C Galactosyl_T Glyco_tranf_2_2
Other DBs
NCBI-GeneID: 337876
NCBI-ProteinID: NP_787052
OMIM: 609963
HGNC: 24293
Ensembl: ENSG00000198108
UniProt: Q70JA7
Position
5:129903979..130186634
AA seq 882 aa
MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQ
QPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRRGREPEG
ATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTA
QKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSF
MMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKL
GLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWS
YEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYR
TIQLHRESALMSKLSNTEVSKEDQQLGVIPSFNHFQPRERNEVIEWEFLTGKLLYSAAEN
QPPRQSLSSILRTALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVNPMHGVEYILD
LLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSETQSFSFISNS
LKILSSFQGAKEMGGHNEKKVHILVPLIGRYDIFLRFMENFENMCLIPKQNVKLVIILFS
RDSGQDSSKHIELIKGYQNKYPKAEMTLIPMKGEFSRGLGLEMASAQFDNDTLLLFCDVD
LIFREDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGNPPTDDYFIFSKKTGFWRDYGY
GITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDP
NLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRYNRTLS
NT seq 2649 nt   +upstreamnt  +downstreamnt
atggctgtgcgctctcgccgcccgtggatgagcgtggcattagggctggtgctgggcttc
accgccgcgtcctggctcatcgcccccagggtggcggagctgagcgagaggaagagacgt
ggctccagcctctgctcctactacggtcgctctgctgctggcccccgcgccggcgctcag
cagccgctcccccagccccagtcccgaccacggcaggagcagtcgccgccccccgcgcgc
caggatctccaggggccaccgctgcccgaggcagcacccgggatcaccagttttcgaagc
agcccctggcagcagccacctccgctgcagcagcggcggcgaggacgcgagcctgagggc
gcgacggggcttcccggtgctccagcggccgagggggagcccgaggaggaggacgggggc
gcggctgggcagcggagagacggccggccggggagtagccacaacggcagcggggacggg
ggcgctgccgccccgagcgcccgaccccgggacttcctgtacgtgggggtgatgaccgcg
cagaagtacctgggcagccgcgcgctggccgcgcagcggacctgggcgcgtttcatcccg
ggccgcgtggagttcttttccagccagcagccccccaacgccggccagcccccgccaccc
ctgcctgtcatcgcgctaccgggtgtggacgactcctatcctccccagaaaaagtccttc
atgatgatcaagtacatgcacgaccactacctggacaagtatgagtggttcatgcgcgcc
gacgacgatgtctacatcaaaggtgataaattagaagagtttcttagatcgctaaacagc
agtaagcctctctacctgggacagactggcctggggaatattgaagagcttggaaagctg
ggactggagcctggggaaaacttctgtatgggaggacctggcatgatctttagccgagaa
gttctcaggaggatggtgccacatattggtgaatgccttagagaaatgtacacgactcat
gaggatgtggaagtaggaagatgcgttcgccgttttggtgggactcagtgtgtctggtct
tacgagatgcaacaactgttccatgaaaattatgaacacaatcggaagggttacatccaa
gaccttcacaatagcaaaatccatgcagccataacacttcatcccaacaaaaggcctgca
taccaatacaggctgcataattacatgctcagccgcaaaatttctgaacttcgctaccgc
accatccagctccacagggaaagtgccctgatgagcaagctcagtaacacagaagtgagc
aaagaggaccagcagctgggagtgataccttctttcaaccacttccagcctcgggagaga
aatgaagtgatagaatgggagttcctgacagggaagcttctatactcagcagctgagaac
cagccccctcgacagagcctcagtagcattttaagaacagcactggatgataccgtccta
caggtgatggagatgatcaatgagaatgccaagagcagaggacggctcattgacttcaag
gaaattcagtatggctaccgcagagttaaccccatgcacggggtggagtacattttggat
ttactccttttatacaaaagacacaagggaaggaaactgactgtgccagtgagacgtcat
gcctatcttcagcagttgttcagcaagcctttcttcagagagaccgaagagctagatgtc
aacagtcttgtggagagtattaacagtgaaactcagtcattctcctttatatctaattct
ttaaagatattatcttcttttcaaggtgccaaagaaatgggagggcacaatgaaaagaaa
gtacacattctcgttcctctcatcggaaggtatgacattttcttgagattcatggagaac
tttgaaaacatgtgtcttatcccaaagcagaatgtaaagttggtcattatccttttcagt
agggattctggccaagactccagcaagcatattgagctgataaaagggtaccagaacaag
taccccaaagcagaaatgaccctgatcccaatgaagggagagttttccagaggtcttggt
cttgaaatggcttctgcccagtttgacaatgacactttgctgctattttgtgatgttgac
ttgatcttcagagaagattttctccaacgatgtagagacaatacaattcagggacaacag
gtgtactatcccatcatctttagccagtatgacccaaaggtaacaaacgggggaaatcct
cccactgatgattacttcatattctcaaaaaagactggattttggagagactatggatat
ggcatcacctgtatttacaaaagtgatcttctaggtgcaggtggatttgatacctcaata
caaggctggggactagaagatgtagatctctacaataaagtcattctatctggcttaagg
ccattcagaagccaagaagtaggagtggtgcatattttccatccagttcattgtgatcct
aacttggaccctaagcagtataagatgtgcttaggatccaaggcaagtactttcgcctca
accatgcaactggctgaactctggcttgaaaaacatttaggtgtcaggtacaatcgaact
ctctcctga

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