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KEGG   Homo sapiens (human): 2326
Entry
2326              CDS       T01001                                 
Symbol
FMO1
Name
(RefSeq) flavin containing dimethylaniline monoxygenase 1
  KO
K00485  dimethylaniline monooxygenase (N-oxide forming) / hypotaurine monooxygenase [EC:1.14.13.8 1.8.1.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00430  Taurine and hypotaurine metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00430 Taurine and hypotaurine metabolism
    2326 (FMO1)
  09111 Xenobiotics biodegradation and metabolism
   00982 Drug metabolism - cytochrome P450
    2326 (FMO1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.8  flavin-containing monooxygenase
     2326 (FMO1)
SSDB
Motif
Pfam: FMO-like Pyr_redox_3 Lys_Orn_oxgnase Pyr_redox_2 NAD_binding_8 DAO NAD_binding_9 MurD-like_N 2-Hacid_dh_C
Other DBs
NCBI-GeneID: 2326
NCBI-ProteinID: NP_001269622
OMIM: 136130
HGNC: 3769
Ensembl: ENSG00000010932
UniProt: Q01740 B2RCG5
Position
1:171248494..171285978
AA seq 532 aa
MAKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVS
NSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLKHIQFKTKVCSVTKCSDSA
VSGQWEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKGQYFHSRQYKHPD
IFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQ
NMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIR
PSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAH
LQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPSWF
GLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGK
WEGARNAIMTQWDRTFKVIKARVVQESPSPFESFLKVFSFLALLVAIFLIFL
NT seq 1599 nt   +upstreamnt  +downstreamnt
atggccaagcgagttgccattgtgggagctggggtcagcggcctggcctccatcaagtgc
tgtctggaagaaggactggagcccacctgctttgagaggagcgatgaccttggggggctg
tggagattcaccgaacatgttgaagaaggcagagccagtctctacaagtctgtggtttcc
aacagctgcaaggagatgtcttgttactcagactttccattcccagaagattatccaaac
tatgtgccaaattctcaattcctggaatatctcaaaatgtatgcaaaccactttgacctt
ctgaaacacattcaattcaagaccaaagtctgcagtgtaacaaaatgctcagattctgct
gtctctggccaatgggaggtggtcactatgcatgaagagaagcaagagtcagccatcttt
gatgctgtcatggtctgcactggctttcttactaatccttatttgccactggattccttt
ccaggtattaatgcctttaaaggccagtactttcatagccggcaatataagcatccagat
atatttaaggacaagagagtccttgtgattggaatgggaaattctggcacagacattgct
gtggaggccagccacctggcggaaaaggtgttcctcagcaccaccggagggggatgggtg
atcagccgaatctttgactcgggctacccatgggacatggtgttcatgacacgctttcag
aacatgttgagaaattccctcccaaccccaattgtgacttggttgatggagcgaaagata
aacaactggctcaatcatgcaaattacggcttaataccagaagacaggactcagctgaaa
gagtttgtgctaaatgatgagctcccaggacgcatcatcactgggaaagtgttcatcagg
ccaagcataaaagaggtaaaggaaaactctgtcatatttaacaatacttcaaaggaagag
cctattgacatcattgtctttgccactggatacacatttgctttccccttccttgatgag
tctgtagtgaaagttgaagatggccaggcctcactgtacaagtatatcttccctgcacat
ctgcaaaagccaaccctggccattattggcctcatcaaacccttgggctccatgatacct
acaggagaaacacaagctcggtgggctgttcgagtcctgaaaggtgtaaataagttacca
ccaccaagtgtcatgatagaggaaattaatgcaaggaaagaaaacaagcccagttggttt
ggcttgtgctactgcaaggctttacaatcagattatatcacatacatagatgaactcctg
acctatatcaatgcaaaacccaacctgttctctatgctcctaacggatccacatctggct
ctgaccgtcttctttggcccatgctcaccataccagttccgcttgactggcccaggaaaa
tgggaaggagccagaaatgccatcatgacccagtgggaccgaacattcaaggtcatcaaa
gctcgagttgtacaagagtctccatctccctttgaaagttttcttaaagtctttagcttt
ctggctttgcttgtggctatttttctgattttcctataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (30)   
   RefSeq(nuc) (12)   
   GenBank (9)   
   EMBL (9)   
Protein domain (9)   
   Pfam (9)   
All databases (85)   

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