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KEGG   Equus asinus (ass): 106822932
Entry
106822932         CDS       T04645                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1 isoform X1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
eai  Equus asinus (ass)
Pathway
eai00230  Purine metabolism
eai01100  Metabolic pathways
eai01522  Endocrine resistance
eai04015  Rap1 signaling pathway
eai04020  Calcium signaling pathway
eai04022  cGMP-PKG signaling pathway
eai04024  cAMP signaling pathway
eai04062  Chemokine signaling pathway
eai04072  Phospholipase D signaling pathway
eai04081  Hormone signaling
eai04114  Oocyte meiosis
eai04211  Longevity regulating pathway
eai04213  Longevity regulating pathway - multiple species
eai04261  Adrenergic signaling in cardiomyocytes
eai04270  Vascular smooth muscle contraction
eai04371  Apelin signaling pathway
eai04540  Gap junction
eai04611  Platelet activation
eai04713  Circadian entrainment
eai04714  Thermogenesis
eai04720  Long-term potentiation
eai04723  Retrograde endocannabinoid signaling
eai04724  Glutamatergic synapse
eai04725  Cholinergic synapse
eai04727  GABAergic synapse
eai04750  Inflammatory mediator regulation of TRP channels
eai04911  Insulin secretion
eai04912  GnRH signaling pathway
eai04913  Ovarian steroidogenesis
eai04914  Progesterone-mediated oocyte maturation
eai04915  Estrogen signaling pathway
eai04916  Melanogenesis
eai04918  Thyroid hormone synthesis
eai04921  Oxytocin signaling pathway
eai04923  Regulation of lipolysis in adipocytes
eai04925  Aldosterone synthesis and secretion
eai04926  Relaxin signaling pathway
eai04927  Cortisol synthesis and secretion
eai04928  Parathyroid hormone synthesis, secretion and action
eai04934  Cushing syndrome
eai04935  Growth hormone synthesis, secretion and action
eai04970  Salivary secretion
eai04971  Gastric acid secretion
eai04972  Pancreatic secretion
eai04976  Bile secretion
eai05032  Morphine addiction
eai05142  Chagas disease
eai05146  Amoebiasis
eai05163  Human cytomegalovirus infection
eai05166  Human T-cell leukemia virus 1 infection
eai05200  Pathways in cancer
eai05207  Chemical carcinogenesis - receptor activation
eai05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:eai00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    106822932 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    106822932 (ADCY1)
   04072 Phospholipase D signaling pathway
    106822932 (ADCY1)
   04024 cAMP signaling pathway
    106822932 (ADCY1)
   04022 cGMP-PKG signaling pathway
    106822932 (ADCY1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    106822932 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    106822932 (ADCY1)
   04062 Chemokine signaling pathway
    106822932 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    106822932 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    106822932 (ADCY1)
   04913 Ovarian steroidogenesis
    106822932 (ADCY1)
   04915 Estrogen signaling pathway
    106822932 (ADCY1)
   04921 Oxytocin signaling pathway
    106822932 (ADCY1)
   04926 Relaxin signaling pathway
    106822932 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    106822932 (ADCY1)
   04918 Thyroid hormone synthesis
    106822932 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    106822932 (ADCY1)
   04925 Aldosterone synthesis and secretion
    106822932 (ADCY1)
   04927 Cortisol synthesis and secretion
    106822932 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    106822932 (ADCY1)
   04971 Gastric acid secretion
    106822932 (ADCY1)
   04972 Pancreatic secretion
    106822932 (ADCY1)
   04976 Bile secretion
    106822932 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    106822932 (ADCY1)
   04727 GABAergic synapse
    106822932 (ADCY1)
   04725 Cholinergic synapse
    106822932 (ADCY1)
   04720 Long-term potentiation
    106822932 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    106822932 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    106822932 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    106822932 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    106822932 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    106822932 (ADCY1)
   04714 Thermogenesis
    106822932 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106822932 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    106822932 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    106822932 (ADCY1)
   05163 Human cytomegalovirus infection
    106822932 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    106822932 (ADCY1)
   05142 Chagas disease
    106822932 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    106822932 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    106822932 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    106822932 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    106822932 (ADCY1)
Enzymes [BR:eai01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     106822932 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom HNOBA
Other DBs
NCBI-GeneID: 106822932
NCBI-ProteinID: XP_014683825
Position
10:315677..467829
AA seq 952 aa
MFGVFVRILAERSQRKSFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK
PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR
RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL
CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF
LKAHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS
NVMTCEDDDKRRALRTASEKLRNRSSFSANVVYTTPGTRVNRYISRLLEARQPELEMADL
NFFTLKYKQAERERKYHQLQDEYFTSAVVLALALAALFSLVYLLIIPQNLAVLLLLVFSI
CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNG
SLVFLSSGGRSPVLPAPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLSVLTASYIL
VLELSGYTKAVGGGTVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAVQAEEERD
DMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIEL
DGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGAKAKKCI
SSHLGTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVN
VASRMDSTGVQGRIQVTEEVHRLLRRGAYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQ
SRTAENDPSRADHGPPPCARCGWPPRHSWAGGSAGLGDRPWASRPTPAPWSSWKGGLAEP
TLAAVGTGRECSGRRAPGGSSKDQPCQQSRTGGQQLGWERGAAQAGPEAAGQ
NT seq 2859 nt   +upstreamnt  +downstreamnt
atgttcggcgtctttgtgaggatcctggccgagcgctcccagaggaagtccttcctgcag
gcccgaaactgcatcgaggaccggctgcgactggaggacgagaatgagaagcaggagcgg
ctgctcatgagtctcttgccccggaacgtcgccatggagatgaaggaggacttcctgaag
ccccccgagaggattttccacaagatttacatccagcggcatgacaacgtgagcatcctc
ttcgcagacatcgtgggcttcacgggcttggcgtctcagtgcacggcccaggagctggtg
aaactcctcaacgagctcttcggcaagtttgatgaattggccacggagaaccactgccgc
cgcatcaagatcctcggagactgttactactgcgtgtctggcctcacccagcccaagact
gaccacgcccattgctgtgtggagatgggcctggacatgatcgacaccatcacgtctgtg
gccgaggccactgaggtggacctgaacatgcgtgtggggctgcacaccggcagggtcctc
tgcggggtcctgggcctgcgcaagtggcagtatgatgtgtggtccaacgacgtgaccttg
gccaatgtcatggaggccgcaggcctgccggggaaggttcatatcacgaagaccaccctg
gcgtgcttgaatggcgactacgaggtggaaccaggtcatggacacgagaggaacagtttt
ctgaaagctcacaatattgagaccttttttattgtgccatcgcatcggcgaaagatattt
cccgggctgattctctcagacataaagccggccaagaggatgaagttcaagaccgtgtgc
tacctgctggtgcagctcatgcactgccggaagatgttcaaggcggagatccccttctcc
aatgtcatgacctgcgaggatgatgacaagcggagggctttgagaacagcctcggaaaaa
ctcagaaaccgctcgtctttctctgcgaacgttgtgtacaccaccccgggcacgcgcgtc
aataggtacatcagccgcctcctagaagcccgccagccagaactggagatggcagacctg
aacttcttcaccctgaagtacaagcaggctgagcgagagcgaaagtaccaccagctccag
gacgagtacttcaccagcgccgtcgtgctcgccctcgccctggccgccttattcagcctc
gtctaccttctgatcatcccgcagaacttggctgtcctgctcctgctggtgttctccatc
tgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtccagtgttttccaggg
tgcctgacgatccagattcgcaccgtcctgtgtattttcatagtggtcttaatctattct
gtggcccaaggatgtgtggtgggctgtctgccctgggcctggagctccagtcccaacggg
tctctggtgttcctgtcgtccggcggccggagcccagtgctgcctgccccgccctgcgag
tctgcaccccacgccctgctctgtggcctggtgggcaccctcccgctggccatattcctg
cgggtctcttccttgcccaaaatgatcctgctctccgtgctcacggcgtcctacatcctg
gtcctggagctcagcgggtacaccaaggccgtggggggcggcactgtctctgggcgcagc
ttcgagccgattgtggccatcctgctgttctcgtgcacgctggccctgcacgcccggcag
gtggacgtcaagctgcggctggactacctctgggctgtgcaggcagaggaggagcgagac
gacatggagcgggtgaagctggacaataagaggattctcttcaatctcctgccagcccac
gtcgcccagcatttcctcatgtccaacccccggaacatggacctctactaccagtcgtac
tcgcaggtgggcgtcatgttcgcctccatccccaacttcaacgacttctacatcgagctg
gatggcaacaacatgggggtggagtgcctgcgcctcctgaatgagatcattgccgacttc
gacgagctcatggacaaagacttttacaaggacctggagaagatcaagaccattgggagc
acctatatggccgcggtgggattggcgcccacggctggggccaaggctaagaagtgtatc
tcctcccacctcggcacgctggcggatttcgccatcgagatgttcgacgtcctggatgag
atcaactaccagtcttacaatgacttcgtgctccgtgtcggcatcaacgttggccccgtg
gtggctggggtgattggggctcgcaggccgcagtatgacatctggggaaacactgtcaac
gtggccagtcggatggacagcaccggggtccagggcagaatccaggtgacggaggaggtg
caccggctgctgcggcggggtgcgtaccgttttgtgtgccgaggcaaagtcagtgtcaag
gggaagggcgagatgctaacgtacttcctggaaggcaggaccgacggaaatggctcccaa
tccagaacggcggaaaatgatccttccagagcagaccacgggccacccccctgtgcccgc
tgtggctggcctccccgtcacagctgggctgggggctctgcagggctcggggatcgcccc
tgggcctcccggcccacccctgccccctggagcagctggaaaggaggcttagcggagccc
acacttgccgctgtgggcacagggcgtgaatgctctgggcgtcgggcccctgggggctcc
agcaaggaccagccctgccagcagagcaggaccgggggccagcagctgggctgggaaagg
ggagctgcccaggcaggacccgaagcagctgggcagtga

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