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KEGG   Echinops telfairi (small Madagascar hedgehog): 101651425
Entry
101651425         CDS       T08707                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
etf  Echinops telfairi (small Madagascar hedgehog)
Pathway
etf04010  MAPK signaling pathway
etf04020  Calcium signaling pathway
etf04022  cGMP-PKG signaling pathway
etf04024  cAMP signaling pathway
etf04218  Cellular senescence
etf04260  Cardiac muscle contraction
etf04261  Adrenergic signaling in cardiomyocytes
etf04270  Vascular smooth muscle contraction
etf04530  Tight junction
etf04713  Circadian entrainment
etf04723  Retrograde endocannabinoid signaling
etf04724  Glutamatergic synapse
etf04725  Cholinergic synapse
etf04726  Serotonergic synapse
etf04727  GABAergic synapse
etf04728  Dopaminergic synapse
etf04911  Insulin secretion
etf04912  GnRH signaling pathway
etf04921  Oxytocin signaling pathway
etf04924  Renin secretion
etf04925  Aldosterone synthesis and secretion
etf04927  Cortisol synthesis and secretion
etf04929  GnRH secretion
etf04930  Type II diabetes mellitus
etf04934  Cushing syndrome
etf04935  Growth hormone synthesis, secretion and action
etf04973  Carbohydrate digestion and absorption
etf05010  Alzheimer disease
etf05020  Prion disease
etf05022  Pathways of neurodegeneration - multiple diseases
etf05031  Amphetamine addiction
etf05207  Chemical carcinogenesis - receptor activation
etf05410  Hypertrophic cardiomyopathy
etf05412  Arrhythmogenic right ventricular cardiomyopathy
etf05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:etf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    101651425 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    101651425 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    101651425 (CACNA1D)
   04929 GnRH secretion
    101651425 (CACNA1D)
   04921 Oxytocin signaling pathway
    101651425 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    101651425 (CACNA1D)
   04924 Renin secretion
    101651425 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    101651425 (CACNA1D)
   04927 Cortisol synthesis and secretion
    101651425 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    101651425 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    101651425 (CACNA1D)
   04727 GABAergic synapse
    101651425 (CACNA1D)
   04725 Cholinergic synapse
    101651425 (CACNA1D)
   04728 Dopaminergic synapse
    101651425 (CACNA1D)
   04726 Serotonergic synapse
    101651425 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    101651425 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101651425 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    101651425 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101651425 (CACNA1D)
   05020 Prion disease
    101651425 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    101651425 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    101651425 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101651425 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101651425 (CACNA1D)
   05414 Dilated cardiomyopathy
    101651425 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101651425 (CACNA1D)
   04934 Cushing syndrome
    101651425 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:etf04040]
    101651425 (CACNA1D)
Ion channels [BR:etf04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   101651425 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel Na_trans_assoc
Other DBs
NCBI-GeneID: 101651425
NCBI-ProteinID: XP_004715265
Position
Unknown
AA seq 2186 aa
MMMMMMMKKMQHQRQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTALSWQAAIDAAR
QAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSPNSRPARALFCLSLNNPIRRACIS
IVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKII
AYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALRA
FRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTC
FFADSDIVAEEDPAPCAFSGNGRQCAANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVSAENGSG
EGENPGCCGSLWCWWKRSSAAKAEPSGCQRWGQAISKSKLSRRWRRWNRFSRRRCRAAVK
SVSFYWLVIVLVFLNTLTISSEHYDQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQA
YFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVA
SLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQI
LTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESL
NTAQKEEAEEKERKKIARKESLENKKNIKPEVNQIANSDNKVIIDDYREEDEDKDPYPPC
DVPVGEEEEEEEEEEEEEPEVPAGPRPRRISELNMKEKIVPIPEGSAFFILSKTNPIRVG
CHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTAEILLKM
TTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRA
KGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGL
FILYKDGEVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPELLYKAIDSNGENV
GPIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEY
ALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKLFNDAMD
ILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIVDVALSEADPTESESVP
VPTAAPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIA
MLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPG
KLCDPESDYDPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG
PHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPL
NSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGD
DEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAI
SCDLQDDEPEEAKREEEAAEEEMFKRNGALLGNHVNHVNSDRRESLQQTNTTHRPLHVQR
PSMPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPNSTNANLNNANMSKAAHGKRPSVG
NLEHVSENGHHSSHKHDHEPPRRPSIKRTRYYEAYIRSDSGEEQFPTICREEAETHGYFR
DPHSLGEQEYFSSEECYEDDGSPTGSRHHCGFYDRSLARNLELERPWGNHYPHGFLEEED
SPVCYDPGRSPRRRLLPPTPTPNRRPSFNFECLRRQNSQEELPPSPAFPRRTALPLHLMQ
QQIMAVAGLDSSQAQKYSPSHSALSWATPPATPPCQDWTPCYTPLIQVEQTESLDQVNGS
LPSLHRSSWYTDEPDISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYA
RDPKFVSATKHEIADACDLTIDEMESAASHLLSGGVSARANGAMGPVSPQQDCELQDFGP
GYSDEEPDPGRYEEDLADEMICITTL
NT seq 6561 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcaagcggaccacgcg
aacgaggcaaactatgcaagaggcaccagactccccctttctggtgaaggaccaacttct
cagccgaatagctccaagcaaactgccctgtcttggcaagctgcaattgatgctgctaga
caggccaaggctgcccagactatgagcacctccgcgcccccacctgtaggatctctctcc
caaagaaaacgtcagcaatatgccaagagcaaaaaacagggtaactcgcccaacagccga
cctgcccgcgccctcttctgtttatcgctcaacaaccccatccgaagagcctgcattagt
atagtggaatggaaaccctttgacatattcatattattggcgatttttgccaattgtgtg
gccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataacttg
gaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagattata
gcgtatggattattgctacatcctaatgcatatgttaggaatggatggaatttattggat
tttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaaaca
gaaggcggtaaccactccagtggcaaatcaggaggctttgatgtcaaagctctccgcgcc
ttccgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtcctg
aactccattataaaagccatggttccccttcttcacatagcccttttggtattatttgta
atcataatctatgctattataggattggaactttttattggaaaaatgcacaaaacatgc
ttttttgctgactcagatatcgtagctgaagaggacccagcaccatgtgcgttctcaggg
aatggacgccagtgtgccgccaatggcacagagtgtaggagcggctgggttggcccaaat
ggaggcatcaccaactttgataattttgcctttgccatgctcaccgtgtttcagtgtatc
accatggagggctggacagacgtgctctactgggtaaatgatgcgataggatgggaatgg
ccctgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctggtt
cttggtgtccttagtggagaattctctaaggaaagagagaaggcaaaagccaggggcgat
ttccagaagctccgggagaagcagcagctggaagaggatctaaagggctacttggactgg
attacccaagcagaagatatcgatcctgagaatgaggaagaaggaggagaggaaggcaaa
cggaatactagcatgcccaccagtgagacggagtctgtgagcgccgagaacggcagtggg
gagggcgagaaccccggatgctgcggaagtctttggtgctggtggaaaagaagcagtgca
gccaaggctgagccctctgggtgtcagcggtggggtcaagccatctccaagtccaaactc
agccgacgctggcgtcgctggaaccgattcagtcggagaaggtgcagggctgccgtgaag
tctgtctcattttactggctggttatcgtcctggtgtttctcaacactttaaccatctcc
tccgagcactacgaccagcctgactggctgacgcagattcaagacatcgctaacaaagtc
ctcttggcgctgttcacctgtgagatgctggtgaaaatgtacagcttgggcctccaggcg
tatttcgtctccctcttcaaccgctttgactgcttcgtggtatgcggcgggattaccgag
accatcctggtggagctggaaatcatgtcacccctggggatctccgtgtttcggtgtgtg
cgtctcttacgcatcttcaaagtgaccaggcactggacctccctcagcaacctggtggcc
tccttgttaaactccatgaagtccattgcctccctgctgctgctgctcttcctcttcatc
atcatcttctccctgctgggcatgcagctgttcggcggcaagtttaacttcgatgaaacg
caaaccaagcgcagcacctttgacaatttccctcaggcacttttaacagtattccagatc
ctgaccggagaagattggaatgccgtgatgtacgacgggatcatggcttacggggggccg
tcctcttcagggatgatcgtctgcatctacttcatcatcctcttcatttgtggcaactat
attctactgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagtctg
aacacggctcagaaggaggaagcagaagaaaaggaaaggaaaaagattgccaggaaagag
agcctggagaataaaaagaacatcaagccggaggtcaaccagatagccaacagtgacaac
aaggttatcatcgatgactatcgggaagaggatgaggacaaggacccctatccaccgtgt
gatgtgccagtaggggaagaggaagaagaggaggaggaggaggaggaggaggagcctgag
gtgcctgctggtccccgtcctcgaagaatctcagagttgaacatgaaggagaaaatcgtc
cccatccctgaaggaagcgccttcttcattcttagtaagaccaacccgatccgagtgggc
tgccacaagctcatcaaccaccacatcttcaccaacctcatccttgtcttcatcatgctg
agcagcgctgccctggccgctgaggaccccatccgcagccactccttccggaacactatt
ctgggttactttgactatgccttcacagccatctttactgctgaaatcctgttaaagatg
acgactttcggggctttccttcacaaaggagctttctgcaggaactacttcaatctgctg
gacatgctggtggtgggggtgtctctggtgtcatttgggattcaatccagtgccatctcg
gtggtgaagattctgagggtcttaagagttctaaggcccctcagggccatcaacagagca
aaaggacttaagcacgtggtccagtgtgtcttcgtggccatccgcacaatcggcaacatc
atgatcgtcaccaccctcctgcagttcatgtttgcctgcatcggggtgcagctgttcaag
ggaaagttctatcgctgcacagatgaagccaaaagtaaccctgaagaatgcagggggctg
ttcattctctacaaggacggggaagttgataaccccgtggttcgtgagaggatctggcaa
aatagtgatttcaactttgacaacgtcctgtcggctatgatggcactcttcacggtctcc
acgtttgagggttggcccgagttgctgtataaggcgatcgactccaacggggagaatgta
ggcccaatctacaactaccgcgtggagatctccatcttcttcatcatctacatcatcatc
gtggccttcttcatgatgaacatctttgtcggtttcgtcatcgtgacctttcaggagcag
ggggagaaggagtacaagaactgtgagctggacaaaaatcagcgccagtgtgttgaatat
gccttgaaagcccgtcctttgcgaagatacatccccaaaaatccctaccagtacaagttc
tggtacgtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaac
acactctgcttggccatgcagcactatgagcagtcgaagctgtttaatgatgccatggac
attctgaacatggtcttcaccggggtcttcacagtggagatggttttgaaagtcattgca
tttaaacctaaggggtactttagtgacgcctggaacacctttgactccctcatcgtcatc
ggcagcatagtagacgtggccctcagcgaagctgacccaactgaaagtgaaagtgtccct
gtcccaactgctgcgcctgggaactctgaagagagcaatagaatctccatcacctttttc
cgtcttttccgagtgatgcgactggtgaagctgctcagcaggggggaaggcattcggaca
ctgctatggactttcattaagtccttccaggccctcccttacgtggccctgctcatagcc
atgctgttcttcatctacgctgtcattggcatgcagatgtttgggaaagttgccatgaga
gacaacaaccagatcaatagaaacaacaacttccaaacattcccccaggcagtgctgctg
ctcttcagatgtgccactggagaggcctggcaggagatcatgctggcctgcctccctggg
aagctctgtgacccagaatccgactatgaccccggcgaggagtacacgtgcgggagcaac
tttgccatcgtttacttcatcagcttttacatgctctgtgcattcctgatcatcaatctg
tttgtggccgtcatcatggacaactttgattatctgacccgggactggtctattctgggg
cctcaccatctagatgaattcaaacgcatatggtcagaatatgaccctgaggccaaggga
aggatcaaacacctggatgtggtcacactgcttcgacgcatccagccaccgctgggattt
gggaaattgtgtccacaccgggtggcctgcaagagattagttgctatgaacatgcctctc
aatagtgacgggaccgtcatgtttaatgcaaccttgtttgccttggtccggactgctctc
aaaatcaagacggaagggaacctggaacaagctaatgaagagcttcgagctgtgataaag
aaaatctggaagaaaaccagcatgaaactgcttgaccaagttgtccctccagctggtgat
gatgaggtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaa
ttcaagaaacgcaaagagcaaggcctggtggggaagtacccggcgaagaacaccacgatt
gccctacaggcgggattaaggacacttcatgatattgggccagagatccggagagctata
tcatgtgatttgcaagatgatgagccagaggaagcaaaacgagaagaagaagcagcagaa
gaagaaatgttcaaaagaaatggtgccctgcttggaaaccatgtcaatcatgttaatagt
gataggagagagtcccttcagcagaccaataccacccaccgtcccctgcatgtccaaagg
ccttcaatgccgcctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcg
gtgtgtcataaccatcataaccataattccataggaaagcaagttcccaactcaacaaat
gccaatctcaataatgccaatatgtccaaagctgcccatggaaagcggcccagcgttggg
aaccttgagcatgtatctgaaaatgggcatcactcctcccacaagcatgaccatgaacct
ccaagaaggcccagtattaaaagaacccgctattacgaagcttacattaggtctgactct
ggggaggagcagttccccactatttgccgggaagaggcagagacccacggctacttcagg
gacccccactccttgggggagcaggagtatttcagcagtgaggagtgctatgaggacgac
ggctcgcccaccggaagcaggcaccactgtggcttctacgacagatccctagcccgcaac
ttagagctggagaggccctggggcaaccattaccctcacggcttcctggaggaagaggac
tcgcctgtctgctatgaccccgggaggtctcccaggagacggctactacctccaacccca
acacccaaccggagaccctccttcaacttcgagtgcctgcgcaggcagaacagccaggag
gagctcccgccgtcgcctgccttcccccgccgcacagccctgcctctgcacctgatgcag
caacagatcatggcagttgctggcctagattcaagccaggcccagaagtactccccgagc
cactcggccctctcatgggccactcctccagcaacccctccctgccaggactggacgccc
tgctacacccccctgatccaggtagagcagaccgagtccctggaccaggtcaacggcagc
ctgccgtccctgcaccgcagctcctggtacacggatgagcccgacatctcctatcggacg
ttcacgccggccagcctgactgtccccagcagcttccggaacaaaaacagcgacaagcag
aggagtgcggacagcctggtggaggcagtcctcatttctgaaggcttaggacggtacgca
agggaccccaaatttgtgtcggccacaaagcatgaaattgccgatgcctgtgacctcacc
atcgatgagatggagagtgccgccagccacctgcttagcgggggtgtgagtgcccgggcc
aacggtgccatgggccccgtctcaccgcagcaggactgtgagctacaagacttcggtcct
ggctacagcgacgaagagccagaccctgggagatacgaggaggacctggcagatgaaatg
atatgcatcaccaccttgtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (35)   
   KEGG PATHWAY (35)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (6)   
   Pfam (6)   
All databases (67)   

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