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KEGG   DRUG: ベンラファキシン塩酸塩
エントリ  
D00821                      Drug                                   
一般名   
ベンラファキシン塩酸塩 (JAN);
Venlafaxine hydrochloride (JAN/USP)
商品名   
イフェクサー (ヴィアトリス製薬)
米国の商品 
EFFEXOR (Viatris Specialty LLC), EFFEXOR (Wyeth Pharmaceuticals LLC)
  後発品
VENLAFAXINE (A-S Medication Solutions), VENLAFAXINE (A-S Medication Solutions), VENLAFAXINE (A-S Medication Solutions), VENLAFAXINE (Ajanta Pharma USA), VENLAFAXINE (Alembic Pharmaceuticals Limited), VENLAFAXINE (Alembic Pharmaceuticals), VENLAFAXINE (American Health Packaging), VENLAFAXINE (Aphena Pharma Solutions - Tennessee), VENLAFAXINE (Ascend Laboratories), VENLAFAXINE (Aurobindo Pharma Limited), VENLAFAXINE (BluePoint Laboratories), VENLAFAXINE (Bryant Ranch Prepack), VENLAFAXINE (Bryant Ranch Prepack), VENLAFAXINE (Bryant Ranch Prepack), VENLAFAXINE (Bryant Ranch Prepack), VENLAFAXINE (Bryant Ranch Prepack), VENLAFAXINE (Cadila Pharmaceuticals Limited), VENLAFAXINE (Cadila Pharmaceuticals Limited), VENLAFAXINE (Coupler LLC), VENLAFAXINE (Coupler LLC), VENLAFAXINE (Coupler LLC), VENLAFAXINE (Coupler LLC), VENLAFAXINE (Dr. Reddy's Laboratories), VENLAFAXINE (Edenbridge Pharmaceuticals LLC.), VENLAFAXINE (Golden State Medical Supply), VENLAFAXINE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), VENLAFAXINE (Lannett Company), VENLAFAXINE (Modavar Pharmaceuticals LLC), VENLAFAXINE (Northwind Pharmaceuticals), VENLAFAXINE (Northwind Pharmaceuticals), VENLAFAXINE (Northwind Pharmaceuticals), VENLAFAXINE (Northwind Pharmaceuticals), VENLAFAXINE (NuCare Pharmaceuticals), VENLAFAXINE (NuCare Pharmaceuticals), VENLAFAXINE (NuCare Pharmaceuticals), VENLAFAXINE (NuCare Pharmaceuticals), VENLAFAXINE (NuCare Pharmaceuticals), VENLAFAXINE (PD-Rx Pharmaceuticals), VENLAFAXINE (Proficient Rx LP), VENLAFAXINE (Proficient Rx LP), VENLAFAXINE (Proficient Rx LP), VENLAFAXINE (Proficient Rx LP), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (REMEDYREPACK), VENLAFAXINE (Rising Pharma Holdings), VENLAFAXINE (ST. MARY'S MEDICAL PARK PHARMACY), VENLAFAXINE (St. Mary's Medical Park Pharmacy), VENLAFAXINE (St. Mary's Medical Park Pharmacy), VENLAFAXINE (St. Mary's Medical Park Pharmacy), VENLAFAXINE (Sun Pharmaceutical Industries), VENLAFAXINE (Zydus Lifesciences Limited), VENLAFAXINE (Zydus Pharmaceuticals USA), VENLAFAXINE (Zydus Pharmaceuticals USA), VENLAFAXINE HCL (Advanced Rx Pharmacy of Tennessee), VENLAFAXINE HCL ER (Direct_Rx), VENLAFAXINE HCL ER (Direct_Rx), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (A-S Medication Solutions), VENLAFAXINE HYDROCHLORIDE (Advagen Pharma), VENLAFAXINE HYDROCHLORIDE (Advanced Rx Pharmacy of Tennessee), VENLAFAXINE HYDROCHLORIDE (Advanced Rx Pharmacy of Tennessee), VENLAFAXINE HYDROCHLORIDE (Advanced Rx Pharmacy of Tennessee), VENLAFAXINE HYDROCHLORIDE (Advanced Rx Pharmacy of Tennessee), VENLAFAXINE HYDROCHLORIDE (Advanced Rx of Tennessee), VENLAFAXINE HYDROCHLORIDE (Advanced Rx of Tennessee), VENLAFAXINE HYDROCHLORIDE (Advanced Rx of Tennessee), VENLAFAXINE HYDROCHLORIDE (Advanced Rx of Tennessee), VENLAFAXINE HYDROCHLORIDE (Alembic Pharmaceuticals Limited), VENLAFAXINE HYDROCHLORIDE (Alembic Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (American Health Packaging), VENLAFAXINE HYDROCHLORIDE (Amneal Pharmaceuticals LLC), VENLAFAXINE HYDROCHLORIDE (Annora Pharma Private Limited), VENLAFAXINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), VENLAFAXINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), VENLAFAXINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), VENLAFAXINE HYDROCHLORIDE (Ascent Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Asclemed USA), VENLAFAXINE HYDROCHLORIDE (Aurobindo Pharma Limited), VENLAFAXINE HYDROCHLORIDE (AvKARE), VENLAFAXINE HYDROCHLORIDE (BluePoint Laboratories), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Bryant Ranch Prepack), VENLAFAXINE HYDROCHLORIDE (Camber Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Camber Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Cardinal Health 107), VENLAFAXINE HYDROCHLORIDE (Chartwell RX), VENLAFAXINE HYDROCHLORIDE (Dr. Reddy's Laboratories Limited), VENLAFAXINE HYDROCHLORIDE (Dr.Reddy's Laboratories), VENLAFAXINE HYDROCHLORIDE (Dr.Reddys Laboratories), VENLAFAXINE HYDROCHLORIDE (Drug Ocean LLC), VENLAFAXINE HYDROCHLORIDE (Epic Pharma), VENLAFAXINE HYDROCHLORIDE (Granules Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Lannett Company), VENLAFAXINE HYDROCHLORIDE (Macleods Pharmaceuticals Limited), VENLAFAXINE HYDROCHLORIDE (Major Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (NCS HealthCare of KY), VENLAFAXINE HYDROCHLORIDE (NCS HealthCare of KY), VENLAFAXINE HYDROCHLORIDE (Nivagen Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Northwind Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Nostrum Laboratories), VENLAFAXINE HYDROCHLORIDE (NuCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (NuCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (NuCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (NuCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (NuCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (NuCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (NuCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Preferred Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Proficient Rx LP), VENLAFAXINE HYDROCHLORIDE (Proficient Rx LP), VENLAFAXINE HYDROCHLORIDE (Proficient Rx LP), VENLAFAXINE HYDROCHLORIDE (Proficient Rx LP), VENLAFAXINE HYDROCHLORIDE (Proficient Rx LP), VENLAFAXINE HYDROCHLORIDE (Proficient Rx LP), VENLAFAXINE HYDROCHLORIDE (Proficient Rx LP), VENLAFAXINE HYDROCHLORIDE (QPharma), VENLAFAXINE HYDROCHLORIDE (QUALLENT PHARMACEUTICALS HEALTH LLC), VENLAFAXINE HYDROCHLORIDE (Quality Care Products), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (REMEDYREPACK), VENLAFAXINE HYDROCHLORIDE (Rising Pharma Holdings), VENLAFAXINE HYDROCHLORIDE (St. Marys Medical Park Pharmacy), VENLAFAXINE HYDROCHLORIDE (Sun Pharmaceutical Industries), VENLAFAXINE HYDROCHLORIDE (Teva Pharmaceuticals USA), VENLAFAXINE HYDROCHLORIDE (Teva Pharmaceuticals USA), VENLAFAXINE HYDROCHLORIDE (Trigen Laboratories), VENLAFAXINE HYDROCHLORIDE (Vertical Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (XLCare Pharmaceuticals), VENLAFAXINE HYDROCHLORIDE (Yaopharma), VENLAFAXINE HYDROCHLORIDE (Zydus Lifesciences Limited), VENLAFAXINE HYDROCHLORIDE (Zydus Lifesciences Limited), VENLAFAXINE HYDROCHLORIDE (Zydus Lifesciences Limited), VENLAFAXINE HYDROCHLORIDE (Zydus Pharmaceuticals USA), VENLAFAXINE HYDROCHLORIDE (Zydus Pharmaceuticals USA), VENLAFAXINE HYDROCHLORIDE, EXTENDED RELEASE (Edenbridge Pharmaceuticals LLC.)
組成式   
C17H27NO2. HCl
質量    
313.1809
分子量   
313.86
構造式   
Simcomp   
クラス   
精神神経系用薬
 DG01658  セロトニン・ノルアドレナリン再取り込み阻害薬 (SNRI)
代謝酵素基質薬
 DG01644  CYP2D6基質薬
 DG01633  CYP3A/CYP3A4基質薬
  DG02913  CYP3A4基質薬
コード   
薬効分類: 1179
ATCコード: N06AX16
化学構造グループ: DG00959
商品 (DG00959): D00821<JP/US> D12403<US>
効能    
抗うつ薬, セロトニン・ノルアドレナリン再取り込み阻害薬
  疾患
うつ病・うつ状態 [DS:H01646]
ターゲット 
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
  パスウェイ
hsa04721  シナプス小胞サイクル
hsa04726  セロトニン作動性シナプス
代謝    
Enzyme: CYP2D6 [HSA:1565]; CYP3A4 [HSA:1576]
相互作用  

構造マップ 
map07027  抗うつ薬
map07234  神経伝達物質トランスポーター阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   117  精神神経用剤
    1179  その他の精神神経用剤
     D00821  ベンラファキシン塩酸塩 (JAN)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N06 精神賦活薬
   N06A 抗うつ薬
    N06AX その他の抗うつ薬
     N06AX16 ベンラファキシン
      D00821  ベンラファキシン塩酸塩 (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗うつ薬
  SSRIs/SNRIs(選択的セロトニン/ノルアドレナリン再取り込み阻害薬)
   ベンラファキシン
    D00821  ベンラファキシン塩酸塩 (JAN)
 抗不安薬
  SSRIs/SNRIs(選択的セロトニン/ノルアドレナリン再取り込み阻害薬)
   ベンラファキシン
    D00821  ベンラファキシン塩酸塩 (JAN)
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01658  セロトニン・ノルアドレナリン再取り込み阻害薬 (SNRI)
   DG00959  ベンラファキシン
    D00821  ベンラファキシン塩酸塩
 代謝酵素基質薬
  DG01644  CYP2D6基質薬
   DG00959  ベンラファキシン
    D00821  ベンラファキシン塩酸塩
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00959  ベンラファキシン
     D00821  ベンラファキシン塩酸塩
ターゲットに基づく医薬品分類 [BR:jp08310]
 トランスポーター
  SLC ファミリー
   SLC6
    SLC6A2 (NAT1)
     D00821  ベンラファキシン塩酸塩 (JAN) <JP/US>
    SLC6A4 (HTT)
     D00821  ベンラファキシン塩酸塩 (JAN) <JP/US>
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D00821
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00821
ゲノムバイオマーカー [jp08341.html]
 医薬品応答に影響を与える多型と変異
  D00821
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01658  セロトニン・ノルアドレナリン再取り込み阻害薬 (SNRI)
   DG00959  ベンラファキシン
 代謝酵素基質薬
  DG01644  CYP2D6基質薬
   DG00959  ベンラファキシン
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00959  ベンラファキシン
リンク   
CAS: 99300-78-4
PubChem: 7847886
ChEBI: 9944
LigandBox: D00821
日化辞: J397.344A

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Ontology (8)   
   KEGG BRITE (8)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (4)   
   KEGG DISEASE (4)   
Drug (3)   
   KEGG DGROUP (1)   
   LigandBox (1)   
   SIDER (1)   
Chemical substance (4)   
   PubChem (1)   
   ChEBI (1)   
   HSDB (1)   
   NIKKAJI (1)   
Gene (4)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (2)   
All databases (25)   

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