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KEGG   Cavia porcellus (domestic guinea pig): 100717630
Entry
100717630         CDS       T07777                                 
Symbol
Gck
Name
(RefSeq) glucokinase
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
cpoc  Cavia porcellus (domestic guinea pig)
Pathway
cpoc00010  Glycolysis / Gluconeogenesis
cpoc00052  Galactose metabolism
cpoc00500  Starch and sucrose metabolism
cpoc00520  Amino sugar and nucleotide sugar metabolism
cpoc00524  Neomycin, kanamycin and gentamicin biosynthesis
cpoc01100  Metabolic pathways
cpoc01200  Carbon metabolism
cpoc01250  Biosynthesis of nucleotide sugars
cpoc04910  Insulin signaling pathway
cpoc04911  Insulin secretion
cpoc04917  Prolactin signaling pathway
cpoc04922  Glucagon signaling pathway
cpoc04930  Type II diabetes mellitus
cpoc04950  Maturity onset diabetes of the young
cpoc05230  Central carbon metabolism in cancer
Module
cpoc_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
cpoc_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:cpoc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100717630 (Gck)
   00052 Galactose metabolism
    100717630 (Gck)
   00500 Starch and sucrose metabolism
    100717630 (Gck)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    100717630 (Gck)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100717630 (Gck)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100717630 (Gck)
   04922 Glucagon signaling pathway
    100717630 (Gck)
   04917 Prolactin signaling pathway
    100717630 (Gck)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    100717630 (Gck)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100717630 (Gck)
   04950 Maturity onset diabetes of the young
    100717630 (Gck)
Enzymes [BR:cpoc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100717630 (Gck)
SSDB
Motif
Pfam: Hexokinase_1 Hexokinase_2
Other DBs
NCBI-GeneID: 100717630
NCBI-ProteinID: XP_013003648
Position
Unknown
AA seq 578 aa
MAMDEARSRAQAALTLAEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGNSGELDEFLLEYDRMVDESSVNPGQQLFREAQDHRKHR
NQGNRAGVGKGVTESHVATSEPRWGIGPSPMARLEKVGMGRAGTRVKGGDGDRGVGRGNR
GAGAAQGTEEPAKKPLPGPGPLVGRRGERWVVGPQTNIAGEEAGLGVRGRGDPKMAGDDP
VPVIRATALSRGTVAGAETQAGGERSLPASPCSDPGDRKQIHNILSTLGLRPSATDCDIV
RRACESVSTRAAHMCSAGLAGVINRMRESRSLDMMRITVGVDGSVYKLHPSFKERFHASV
RRLTPRCEITFIESEEGSGRGAALVSAVACKKACMLGQ
NT seq 1737 nt   +upstreamnt  +downstreamnt
atggccatggatgaggcccggagccgagcacaggcagccctgacgctggcggagcagatc
ttggcagagttccagctgcaggaggaggatctgaagaaggtgatgcggcggatgcagaag
gagatggaccgaggcctgaggctggagacccacgaggaggccagcgtgaagatgctgccc
acctacgtgcgttccaccccagaaggctcagaagtcggagacttcctgtccctggacctg
ggaggcaccaacttcagggtgatgctggtgaaggtgggggagggtgaggagggacagtgg
agcgtgaagaccaaacaccagatgtactccatccccgaggacgccatgacaggcactgca
gaaatgctgtttgactacatctctgagtgcatctctgatttcctggacaagcaccagatg
aagcacaagaagctgcccctgggctttaccttctccttccctgtgaggcatgaggacatc
gacaagggcatccttctcaactggaccaagggcttcaaagcctcaggagcagaagggaac
aacatcgtggggcttctgcgagatgccatcaagaggagaggggactttgagatggatgtg
gtggccatggtgaacgacacagtagccacaatgatctcctgctactatgaagaccgccag
tgtgaggtcggcatgatcgtgggcacaggctgcaacgcctgctacatggaggagatgcag
aacgtggagctggtggaaggggacgagggccgcatgtgcgtcaacaccgagtggggcgcc
tttggcaactctggcgaactggacgagttcctgctagagtatgaccgcatggtggacgag
agctccgtgaaccccggtcagcagcttttccgcgaagcacaggaccataggaaacacaga
aaccagggcaatcgggctggggtgggcaaaggcgtcacggagtcccacgtggccacctcg
gaaccacgctggggcattgggccctccccgatggcccgtttggagaaggtgggcatgggg
cgggccgggacccgggtgaaggggggagacggggaccggggtgttgggcgcgggaaccgg
ggcgcgggcgcggcacaggggacggaagaacccgcgaagaaacccctccctgggccgggc
cccttggttggaagaaggggtgagcgttgggttgttggcccccagaccaatatagccggg
gaagaagcgggcctgggggttcgggggcgcggggaccctaaaatggccggggacgaccct
gtccccgtcatccgcgcgacagccctgagccgcggcactgtcgctggagcagagacccag
gccgggggcgagcgaagcctccccgcctcgccctgcagcgacccgggcgaccgcaagcag
atccacaacatcctgagcactctggggctgcggccctccgccaccgactgcgacatcgtg
cgccgcgcctgcgagagcgtgtccacgcgcgccgcgcacatgtgctccgcggggctggcg
ggcgtcatcaaccgcatgcgagagagccgcagcctggacatgatgcgcatcaccgtgggc
gtggacggctcggtgtacaagctgcaccccagcttcaaggagcggttccacgccagcgtg
cgcaggctgacgccccgctgcgaaatcaccttcatcgagtccgaggagggcagcggccgg
ggcgccgcgctggtgtctgcggtggcctgcaagaaggcctgtatgctgggccaatga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (13)   
   RefSeq(pep) (13)   
DNA sequence (13)   
   RefSeq(nuc) (13)   
Protein domain (2)   
   Pfam (2)   
All databases (30)   

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