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KEGG   Cricetulus griseus (Chinese hamster): 100756793
Entry
100756793         CDS       T02813                                 
Symbol
Map2k3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge04010  MAPK signaling pathway
cge04015  Rap1 signaling pathway
cge04218  Cellular senescence
cge04620  Toll-like receptor signaling pathway
cge04664  Fc epsilon RI signaling pathway
cge04668  TNF signaling pathway
cge04714  Thermogenesis
cge04750  Inflammatory mediator regulation of TRP channels
cge04912  GnRH signaling pathway
cge04935  Growth hormone synthesis, secretion and action
cge04936  Alcoholic liver disease
cge05014  Amyotrophic lateral sclerosis
cge05022  Pathways of neurodegeneration - multiple diseases
cge05132  Salmonella infection
cge05135  Yersinia infection
cge05145  Toxoplasmosis
cge05161  Hepatitis B
cge05169  Epstein-Barr virus infection
cge05170  Human immunodeficiency virus 1 infection
cge05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cge05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100756793 (Map2k3)
   04668 TNF signaling pathway
    100756793 (Map2k3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100756793 (Map2k3)
   04664 Fc epsilon RI signaling pathway
    100756793 (Map2k3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    100756793 (Map2k3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100756793 (Map2k3)
  09159 Environmental adaptation
   04714 Thermogenesis
    100756793 (Map2k3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100756793 (Map2k3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100756793 (Map2k3)
   05161 Hepatitis B
    100756793 (Map2k3)
   05169 Epstein-Barr virus infection
    100756793 (Map2k3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    100756793 (Map2k3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100756793 (Map2k3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100756793 (Map2k3)
   05022 Pathways of neurodegeneration - multiple diseases
    100756793 (Map2k3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100756793 (Map2k3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100756793 (Map2k3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cge01001]
    100756793 (Map2k3)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     100756793 (Map2k3)
Protein kinases [BR:cge01001]
 Serine/threonine kinases: STE group
  STE7 family
   100756793 (Map2k3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Seadorna_VP7 Pkinase_fungal APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 100756793
NCBI-ProteinID: XP_027283065
UniProt: A0A8C2QPB0
Position
7:74920145..74942262
AA seq 347 aa
MESPAASPPASLPQTKGKSKRKKDLRITCVSKPPAPNPTPPRNLDSRAFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADKFSPEFVD
FTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtctcccgccgcgagtccaccggccagcttgcctcagaccaaaggaaaatctaaa
aggaaaaaggatttacggataacctgtgtgtccaagccacctgcacccaaccccacacca
ccccggaacctggactcccgggccttcatcaccatcggagacagaaactttgaggtggag
gctgatgacttggtgactatctcagaactgggccgaggagcctacggggtggtggagaag
gtgcgacatgctcagagtggcaccatcatggctgtgaagcgaatccgggccactgtgaac
tcacaagagcagaaacgtctgcttatggacctagatatcaacatgcgcacggtcgattgc
ttctacaccgtcactttctatggtgccctcttcagagagggggatgtgtggatctgcatg
gagctcatggacacttccctggacaagttctaccggaaggtgctggagaagaacatgaca
attccggaggacatcctgggcgagattgctgtgtctatcgtgcgggccctggagcatctg
cacagcaagctgtctgtgatccatagagatgtgaagccgtccaatgtcctcatcaacaag
gaggggcatgtgaagatgtgcgactttggcatcagtggctacctggtggactctgtggca
aagacaatggatgctggttgcaagccttacatggctcctgagaggatcaaccctgagctg
aatcagaagggctacaatgtcaagtctgacgtctggagcctcggcatcaccatgatcgag
atggccattctgcgattcccttatgaatcttgggggacaccgttccagcagctgaagcag
gtggtggaggaaccatccccacagctcccagctgacaagttctcccctgagtttgtggac
ttcaccagccagtgcctaaggaagaaccctgcggagcgcatgagctacctggagctgatg
gaacaccctttcttcaccttgcacaaaactaagaagacagacattgctgcctttgtgaag
gagatcctgggagaggattcatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (9)   
   RefSeq(nuc) (5)   
   GenBank (2)   
   EMBL (2)   
Protein domain (11)   
   Pfam (11)   
All databases (60)   

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