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KEGG   Canis lupus familiaris (dog): 489547
Entry
489547            CDS       T01007                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04015  Rap1 signaling pathway
cfa04218  Cellular senescence
cfa04620  Toll-like receptor signaling pathway
cfa04664  Fc epsilon RI signaling pathway
cfa04668  TNF signaling pathway
cfa04714  Thermogenesis
cfa04750  Inflammatory mediator regulation of TRP channels
cfa04912  GnRH signaling pathway
cfa04935  Growth hormone synthesis, secretion and action
cfa04936  Alcoholic liver disease
cfa05014  Amyotrophic lateral sclerosis
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05132  Salmonella infection
cfa05135  Yersinia infection
cfa05145  Toxoplasmosis
cfa05161  Hepatitis B
cfa05169  Epstein-Barr virus infection
cfa05170  Human immunodeficiency virus 1 infection
cfa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    489547 (MAP2K3)
   04668 TNF signaling pathway
    489547 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    489547 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    489547 (MAP2K3)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    489547 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    489547 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    489547 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    489547 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    489547 (MAP2K3)
   05161 Hepatitis B
    489547 (MAP2K3)
   05169 Epstein-Barr virus infection
    489547 (MAP2K3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    489547 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    489547 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    489547 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    489547 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    489547 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    489547 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    489547 (MAP2K3)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     489547 (MAP2K3)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: STE group
  STE7 family
   489547 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 489547
NCBI-ProteinID: XP_546666
Ensembl: ENSCAFG00000018530
VGNC: 42961
UniProt: A0A8C0RB66
Position
5:42870421..42900078
AA seq 347 aa
MESPASSQPASMPQTKGKSKRKKDLRISCMSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcccccgcctccagtcagcccgctagcatgccccagaccaaagggaaatccaag
aggaagaaggatttacggatatcctgcatgtccaagccacctgtacccaaccccacaccc
ccccggaacctcgactcccggaccttcatcaccattggagataggaactttgaggtggag
gccgatgacctggtgaccatctcagagctgggccgaggagcctacggggtggtagagaag
gtgcgacatgcccagagtggcaccatcatggctgtgaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcggacggtcgactgc
ttctatactgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgctcgataaaaacatgacc
attccagaggacatcctgggggaaattgctgtgtctatcgtgagggctctggagcacctg
cacagcaagctgtcggtgatccatagagacgtgaagccgtccaatgtcctcatcaacaag
gagggccacgtgaagatgtgcgactttgggattagtggctacttggtggattctgtggct
aagacgctggacgctggctgcaagccctacatggctcccgagagaatcaacccagagctt
aaccagaagggctacaatgtcaagtctgatgtctggagtctcggcatcaccatgattgag
atggccattctacggtttccgtatgaatcctgggggactccgttccagcagctgaagcag
gtggtggaagagccatctccccagctcccggccgaccgtttctctcctgagttcgtggac
ttcactgcacagtgcttgaggaagaaccccgcggagcgcatgagctacttggagctgatg
gagcacccattcttcacattgcacaaaaccaagaagacggacattgcggccttcgtgaag
gagatcctgggggaggactcatag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (11)   
   Pfam (11)   
All databases (56)   

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