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KEGG   Castor canadensis (American beaver): 109695052
Entry
109695052         CDS       T04791                                 
Symbol
Rxra
Name
(RefSeq) retinoic acid receptor RXR-alpha isoform X1
  KO
K08524  retinoid X receptor alpha
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan03320  PPAR signaling pathway
ccan04148  Efferocytosis
ccan04151  PI3K-Akt signaling pathway
ccan04659  Th17 cell differentiation
ccan04919  Thyroid hormone signaling pathway
ccan04920  Adipocytokine signaling pathway
ccan04928  Parathyroid hormone synthesis, secretion and action
ccan04932  Non-alcoholic fatty liver disease
ccan04976  Bile secretion
ccan05160  Hepatitis C
ccan05200  Pathways in cancer
ccan05202  Transcriptional misregulation in cancer
ccan05207  Chemical carcinogenesis - receptor activation
ccan05216  Thyroid cancer
ccan05222  Small cell lung cancer
ccan05223  Non-small cell lung cancer
ccan05226  Gastric cancer
ccan05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    109695052 (Rxra)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    109695052 (Rxra)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    109695052 (Rxra)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    109695052 (Rxra)
   04928 Parathyroid hormone synthesis, secretion and action
    109695052 (Rxra)
  09154 Digestive system
   04976 Bile secretion
    109695052 (Rxra)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109695052 (Rxra)
   05202 Transcriptional misregulation in cancer
    109695052 (Rxra)
   05207 Chemical carcinogenesis - receptor activation
    109695052 (Rxra)
  09162 Cancer: specific types
   05226 Gastric cancer
    109695052 (Rxra)
   05216 Thyroid cancer
    109695052 (Rxra)
   05222 Small cell lung cancer
    109695052 (Rxra)
   05223 Non-small cell lung cancer
    109695052 (Rxra)
  09172 Infectious disease: viral
   05160 Hepatitis C
    109695052 (Rxra)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109695052 (Rxra)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    109695052 (Rxra)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ccan03000]
    109695052 (Rxra)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:ccan03310]
    109695052 (Rxra)
Transcription factors [BR:ccan03000]
 Eukaryotic type
  Zinc finger
   Cys4 hepatocyte nuclear factor 4-like
    109695052 (Rxra)
Nuclear receptors [BR:ccan03310]
 2. Hepatocyte nuclear factor 4 like
  2B. Retinoid X receptor (RXR)
   109695052 (Rxra)
SSDB
Motif
Pfam: Hormone_recep Nuc_recep-AF1 zf-C4 tRNA_bind_3
Other DBs
NCBI-GeneID: 109695052
NCBI-ProteinID: XP_020032944
UniProt: A0A8C0WS47
Position
Unknown
AA seq 504 aa
MQSPWLLPPGLLSGRQGSGWMSDSGSSCLLGPYAALLSTRQRLTLTDFSTQVNSSSLSSP
TGRGSMAAPSLHPSLGPGLGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMS
VPTTPTLGFGTGSPQLNSPMNPVSSSEDIKPPIGLNGVLKVPAHPSGNMASFTKHICAIC
GDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAM
GMKREAVQEERQRGKDRNESEVESTSSANEDMPVEKILEAELAVEPKTETYVEANMGLNP
SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSI
AVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNP
DSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFF
FKLIGDTPIDTFLMEMLETPHQMT
NT seq 1515 nt   +upstreamnt  +downstreamnt
atgcagagcccttggctcctgcctccggggctcctgtcaggaaggcagggcagtggctgg
atgtcagactctggctcctcctgtctcctgggtccctatgctgctctcctgagcaccagg
cagcgactcactttgacagacttctccacccaggtgaactcttcgtccctcagctctccg
acaggccggggttccatggccgccccctcactgcatccgtccctggggcctggcctcggc
tccccactggggtcaccggggcagctacactcacccatcagcaccctgagctcacccatc
aatggcatgggccctcccttctccgtcatcagctcccctatgggcccccactccatgtcg
gtgcccaccacacctaccctgggcttcggcactggcagcccgcagctcaactcacccatg
aaccctgtcagcagcagtgaggacatcaaacccccgataggcctcaatggcgtcctcaag
gtccccgcccacccatcagggaacatggcctctttcaccaagcacatctgtgccatctgt
ggggatcgctcctcaggcaagcactatggggtgtacagctgtgagggttgcaagggcttc
ttcaagaggacggtgcgcaaggacctgacctacacctgccgcgacaacaaggactgcctg
atcgacaagcgccagcggaaccggtgccagtactgccgctaccagaagtgcctggccatg
ggtatgaagcgagaagcggtgcaggaggagagacagcggggaaaggaccggaacgagagt
gaggtggagtccacaagtagtgccaacgaggacatgcctgtggagaaaattctggaagcc
gagctggctgtcgagcccaagaccgagacctacgtagaggcaaacatggggttaaacccc
agctcgccaaacgaccctgtcaccaacatctgccaggcagcagacaaacagctcttcacc
cttgtggagtgggccaagaggatcccacacttctctgagctcccgctggacgaccaggtc
atcctgctgcgagcaggctggaacgagctgctcatcgcctccttctcccaccggtccata
gctgtgaaggacgggatcctcctcgctaccgggctgcatgtgcaccgcaacagtgcccac
agtgcaggggtgggcgccatctttgacagggtgctgacagagctggtgtccaaaatgcga
gacatgcagatggacaagacagagctgggctgcctgcgcgccatcgtcctcttcaacccc
gactccaaggggctctcaaacccggctgaggtggaggcactgagggagaaggtgtacgcg
tcgctggaggcttactgcaaacacaagtacccagagcagccgggcaggttcgccaagctc
cttctccgcctgcctgcactgcgctccattgggctcaagtgcctggagcacctcttcttc
ttcaagctcatcggggacacgcccattgacaccttcctcatggagatgctggagacccca
caccagatgacctag

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