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KEGG   Camelus bactrianus (Bactrian camel): 105079596
Entry
105079596         CDS       T07534                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
cbai  Camelus bactrianus (Bactrian camel)
Pathway
cbai04010  MAPK signaling pathway
cbai04020  Calcium signaling pathway
cbai04022  cGMP-PKG signaling pathway
cbai04024  cAMP signaling pathway
cbai04218  Cellular senescence
cbai04260  Cardiac muscle contraction
cbai04261  Adrenergic signaling in cardiomyocytes
cbai04270  Vascular smooth muscle contraction
cbai04530  Tight junction
cbai04713  Circadian entrainment
cbai04723  Retrograde endocannabinoid signaling
cbai04724  Glutamatergic synapse
cbai04725  Cholinergic synapse
cbai04726  Serotonergic synapse
cbai04727  GABAergic synapse
cbai04728  Dopaminergic synapse
cbai04911  Insulin secretion
cbai04912  GnRH signaling pathway
cbai04921  Oxytocin signaling pathway
cbai04924  Renin secretion
cbai04925  Aldosterone synthesis and secretion
cbai04927  Cortisol synthesis and secretion
cbai04929  GnRH secretion
cbai04930  Type II diabetes mellitus
cbai04934  Cushing syndrome
cbai04935  Growth hormone synthesis, secretion and action
cbai04973  Carbohydrate digestion and absorption
cbai05010  Alzheimer disease
cbai05020  Prion disease
cbai05022  Pathways of neurodegeneration - multiple diseases
cbai05031  Amphetamine addiction
cbai05207  Chemical carcinogenesis - receptor activation
cbai05410  Hypertrophic cardiomyopathy
cbai05412  Arrhythmogenic right ventricular cardiomyopathy
cbai05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cbai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    105079596 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    105079596 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    105079596 (CACNA1D)
   04929 GnRH secretion
    105079596 (CACNA1D)
   04921 Oxytocin signaling pathway
    105079596 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    105079596 (CACNA1D)
   04924 Renin secretion
    105079596 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    105079596 (CACNA1D)
   04927 Cortisol synthesis and secretion
    105079596 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105079596 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    105079596 (CACNA1D)
   04727 GABAergic synapse
    105079596 (CACNA1D)
   04725 Cholinergic synapse
    105079596 (CACNA1D)
   04728 Dopaminergic synapse
    105079596 (CACNA1D)
   04726 Serotonergic synapse
    105079596 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    105079596 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105079596 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    105079596 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105079596 (CACNA1D)
   05020 Prion disease
    105079596 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    105079596 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    105079596 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    105079596 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    105079596 (CACNA1D)
   05414 Dilated cardiomyopathy
    105079596 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105079596 (CACNA1D)
   04934 Cushing syndrome
    105079596 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:cbai04040]
    105079596 (CACNA1D)
Ion channels [BR:cbai04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   105079596 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 105079596
NCBI-ProteinID: XP_010966667
Position
Unknown
AA seq 1867 aa
MLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKER
EKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETES
VNTENVSGEGENQGCCGSLWCWWRGRGAAQAGPSGCRRWGQAISKSKLSRRWRRWNRFNR
RRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVK
MYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHW
TSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQ
ALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICDILLNVFLAIAVDNL
ADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDK
DPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPI
RVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEIL
LKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAI
NRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEEC
RGLFILYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYRAIDSNG
ENVGPIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQC
VEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFND
AMDILNMVFTGVFTVEMVLKVIAFKPKVCPHVVGMASHCYVLINVCPAHSVQGYFSDAWN
TFDSLIVIGSIVDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIK
SFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATG
EAWQEIMLACLPGKLCDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMD
NFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHR
VACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTS
MKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNSTIALQAGLR
TLHDIGPEIRRAISCDLQDDEPEETKREEEEDVFKRNGALLGNHVNHVNSDRDSLQQTNT
THRPLHVQRPAVPPASDTEKPLFPPAGNSVCHNRHNHNSIGKQVPSSTNANLNNANMSKA
APGKRPSIGNLEHVSENGHHSSHKHGREPQRRSSIKRTRYYETYIRSDSGDEQFPTICRE
DPEIHGYFRDPHCLGEQEYFGCEDCYEGDSSPTGSRAFLTCDQPLDSLPPSQLASSHPLF
KGLLRTPAKSAAATTTDTQAAAWISSGPEGTITHKASRRMMTRLFATIPGDPQGDAYYLP
PQHSLFHNCMVCSDFSAHRRSSFNFECLRRQSSQEEVPPSPALPHRAALPLHLMQQQIMA
VAGLDSSKAQKYSPSHSTRSWATPPATPSYRDWTPCYTPLIQVERPEALDQVNGSLPSLH
RSSWYTDEPAISYRTFTPASLTVPSSFHSKNSDKQRSADSLVEAVLISEGLGRYARDPKF
VSATKHEIADACLNGNVHPRANGDVGPVSHRQDYELQDFGPGYSDEEPDPGRDEEDLADE
MICITTL
NT seq 5604 nt   +upstreamnt  +downstreamnt
atgctcaccgtgtttcagtgcatcaccatggagggctggacagacgtgctctactggatg
aatgatgctatgggatttgaattgccctgggtgtattttgtcagtctcgtcatctttggg
tcatttttcgtactaaatcttgtacttggtgtattgagcggagaattctcaaaggaaagg
gagaaggctaaagcccggggagacttccagaagctccgggagaagcagcagctggaagag
gatctaaagggctacttggattggatcacccaagcagaggacattgatcctgagaatgaa
gaagaaggaggcgaggaaagcaaacggaataccagcatgcccaccagtgagacagagtct
gtgaatacggagaacgtgagcggggaaggcgagaaccaaggctgctgtgggagcctctgg
tgctggtggagaggaagaggcgctgcgcaggccgggccctctggttgtcggcggtggggt
caagccatctcaaaatccaagctcagccgacgctggcgtcgctggaaccgcttcaatcgc
cgaagatgcagggctgctgtgaagtctgtcacgttttactggctggttattgtcctggtg
tttctcaacaccttaaccatttcctccgagcactacaaccagcctgactggttgacacag
attcaagacattgctaacaaagtccttttggctctgttcacctgcgagatgctggtaaaa
atgtacagcttgggtctccaggcgtatttcgtgtctctttttaatcggtttgattgcttt
gtggtgtgtggcggaattaccgaaaccatcttggtggaactggaaatcatgtctcccctg
ggcatctctgtgtttcgatgtgtgcgcctcctgagaattttcaaagtgaccaggcactgg
acgtccctgagcaacttggtggcatccttgttaaactccatgaagtccatcgcttcgctg
ctgcttctgcttttcctcttcatcatcatcttttccttgcttgggatgcagctgttcggt
ggcaagtttaatttcgacgaaacgcaaaccaagaggagcacctttgataatttccctcaa
gcacttctaacggtgttccagattctgacaggtgaagactggaatgctgtgatgtatgat
ggcatcatggcgtatgggggcccatcatcttcaggaatgattgtctgcatctacttcatc
atcctcttcatctgcgatattctactgaatgtctttttggccattgctgtagacaacttg
gctgatgctgaaagtttgaacactgctcagaaagaggaagctgaagaaaaggaaaggaaa
aagattgccagaaaagaaagcctggaaaataaaaagaacaacaaaccagaagtcaaccag
atagccaacagtgacaacaaggttacaattgacgactaccgagaagaggatgaggacaag
gacccctacccgccttgtgatgtgccagtaggtgaagaggaagaagaggaggaggaggat
gagcctgaggttccagctggcccccgtcctcgcagaatctctgagttgaacatgaaagag
aaaattgcccctattcccgaagggagcgctttcttcattcttagcaagaccaacccgatc
cgagtgggctgccacaagctcatcaaccaccacatcttcaccaacctcatccttgtcttc
atcatgctgagcagcgctgccctggcggctgaggaccccatccgcagccactccttccgg
aacactatactgggttactttgactatgctttcacagccatctttactgttgaaatcctg
ttgaagatgacaacttttggagctttcctccacaaaggggctttctgcaggaactacttc
aacttactggatatgctggttgttggggtatctctggtgtcatttgggatccaatccagt
gccatctctgttgtgaagattctgagggtcttaagggtcctgaggccactcagggcaatc
aacagagcaaaaggacttaagcacgttgtccagtgcgtctttgtggccatccggacaatc
ggcaacatcatgatcgtcaccaccctgctccagttcatgttcgcctgcattggggttcag
ctgttcaagggaaagttctatcgctgtaccgacgaagccaaaagtaaccctgaagaatgc
agagggctcttcatcctctacaaggatggagatgtggataaccctgtggtccgtgagagg
atctggcagaacagtgatttcaactttgacaacgtcctctcagccatgatggctctgttc
acagtctccacgtttgagggctggcccgcgttgctgtacagagccatcgactcgaacgga
gagaacgtcggccccatctacaactaccgcgtggagatctccatcttcttcatcatctac
atcatcatcgtagcgttcttcatgatgaacatctttgtgggcttcgtcatcgtcactttc
caggagcagggggagaaagagtataagaactgtgagctggacaaaaatcagcgtcagtgt
gttgaatacgccttgaaagctcgtcccttgcggagatacatccccaaaaacccctaccag
tacaagttctggtacgtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatc
atgctcaacacactctgcttggccatgcagcactacgagcagtccaagatgtttaatgac
gccatggacatcctgaacatggtcttcactggggttttcactgtcgagatggttttgaaa
gtcattgcttttaaacccaaggtgtgtccccacgtggtcggcatggcgtctcattgctat
gtgctcataaacgtctgccccgcccactctgtccaggggtactttagtgatgcctggaac
acgtttgactccctcatcgtaatcggcagcattgtagacgtggccctcagcgaagctgac
aactctgaagagagcaatagaatctccatcacctttttccgtcttttccgagtgatgcgc
ctggtgaagcttctcagcaggggggaaggcatccggacattgctgtggactttcattaag
tccttccaggcgctcccctatgtcgcccttctcatagccatgctgttcttcatctacgcg
gttatcggcatgcagatgtttgggaaagttgccatgagagataacaaccagatcaacagg
aacaataatttccagacctttcctcaggcagtgctgctgctcttcaggtgtgcgacgggg
gaggcctggcaggaaatcatgctggcctgcctcccagggaagctctgtgaccccgagtcg
gattacaaccctggcgaggagtacacgtgtggaagcaacttcgccatcgtttatttcatc
agtttttacatgctctgtgcgtttctgatcatcaacctgttcgtggctgtcatcatggac
aattttgattatctgacccgggactggtcaattctggggcctcaccatttagatgaattc
aaaagaatatggtccgaatacgaccctgaggcaaagggaaggatcaagcacctggacgtg
gtcactctgctccgccgaatccagcctcccctgggatttgggaaattgtgcccacacaga
gtagcctgtaagagactagttgccatgaacatgccgctcaacagtgatgggacagtcatg
tttaatgcaactctgtttgctttggttcgaacggctcttaagatcaagacggaagggaac
ctggaacaagctaatgaagaactgcgagctgtgatcaagaaaatttggaagaaaaccagc
atgaaacttcttgaccaagttgtccctccagctggtgatgatgaggtaaccgtggggaag
ttctatgccactttcctgatacaggactactttaggaaattcaagaaacggaaagaacaa
ggactggtgggaaaataccccgcgaagaacagcacaattgccctacaggcgggattaagg
acactgcatgacatcgggccagaaatccggcgtgctatatcatgtgatttgcaagatgac
gagccagaggaaacaaaacgagaagaagaagaagatgtattcaaaagaaatggtgccctg
cttggaaaccatgtcaatcatgttaatagtgatagagattcccttcagcagaccaatacc
acccaccgtcccctgcatgtccaaaggcctgcagttccacctgcaagtgatactgagaaa
ccgctgtttcctccagcaggaaattcggtgtgtcataaccgtcataaccataattccata
ggaaagcaagttcccagctcaacaaatgccaatctcaataatgccaatatgtccaaagct
gcccctggaaagcggcccagcattgggaaccttgagcatgtgtctgaaaatgggcatcat
tcctcccacaagcatggccgtgagcctcaaagaaggtccagtattaaaagaacccgctat
tatgaaacttacattaggtctgactcaggagatgagcagttcccaactatttgccgggaa
gatccagagatacacggctactttagggacccccactgcttgggggagcaggagtatttc
ggctgcgaggactgctacgagggcgacagctcgccgaccgggagcagagccttcctcacg
tgtgaccagcccttggactcccttcccccatcccagctggcctcgtcccaccctctcttc
aagggcctgctccgcactcccgcaaagtcggctgcagctactacaaccgacacccaggca
gcagcttggatttcgagcggccccgagggtaccatcacccacaaggcttctcggaggatg
atgactcgcctgtttgctacgattcccggagatccccaaggagacgcctactacctccca
ccccaacatagcttgtttcacaactgcatggtgtgctctgatttctcagcccaccggagg
tcctccttcaacttcgagtgcctgcgccggcagagcagccaggaggaggtcccgccctcc
cccgccctcccccaccgcgcggccctgcctctgcacctgatgcagcaacagatcatggca
gttgctggcctagattccagtaaagcccagaagtactcgccgagccactccacccggtcg
tgggccacccctccagcgaccccatcgtatcgggactggacgccatgctacacccccctg
atccaggtcgagcggccagaggccctggaccaggtcaacggcagcctgccgtccctgcac
cgcagctcgtggtacacggacgagcctgccatctcctatcggaccttcacaccagccagc
ctgaccgtccccagcagcttccacagcaaaaacagtgacaagcagaggagtgcagacagc
ttggtggaggcagtcctgatatctgaaggcttaggacgatatgcgagggacccaaaattt
gtgtcggcaacaaaacacgaaattgccgacgcctgtctgaacgggaacgtgcatccccgg
gccaacggggacgtgggccctgtctcacaccggcaggactatgagctccaggacttcggg
ccgggctacagcgacgaggagccagaccctgggagggatgaggaggacctggcagatgaa
atgatttgcatcaccaccctgtaa

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