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KEGG   Colobus angolensis palliatus (Angola colobus): 105508520
Entry
105508520         CDS       T08744                                 
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
  KO
K05031  cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
Organism
cang  Colobus angolensis palliatus (Angola colobus)
Pathway
cang02010  ABC transporters
cang04024  cAMP signaling pathway
cang04152  AMPK signaling pathway
cang04530  Tight junction
cang04971  Gastric acid secretion
cang04972  Pancreatic secretion
cang04976  Bile secretion
Brite
KEGG Orthology (KO) [BR:cang00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    105508520 (CFTR)
  09132 Signal transduction
   04024 cAMP signaling pathway
    105508520 (CFTR)
   04152 AMPK signaling pathway
    105508520 (CFTR)
 09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    105508520 (CFTR)
   04972 Pancreatic secretion
    105508520 (CFTR)
   04976 Bile secretion
    105508520 (CFTR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:cang02000]
    105508520 (CFTR)
Enzymes [BR:cang01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.1  Enzymes altering polypeptide conformation or assembly
    5.6.1.6  channel-conductance-controlling ATPase
     105508520 (CFTR)
Transporters [BR:cang02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC7 subgroup
    105508520 (CFTR)
SSDB
Motif
Pfam: CFTR_R ABC_membrane ABC_tran SMC_N AAA_29 AAA_21 T2SSE AAA_16 DO-GTPase2 DUF87 RsgA_GTPase MeaB Zeta_toxin MMR_HSR1 nSTAND3 NB-ARC AAA_30 NTPase_1 Intein_splicing
Other DBs
NCBI-GeneID: 105508520
NCBI-ProteinID: XP_011792769
Ensembl: ENSCANG00000033373
UniProt: A0A2K5ITA3
Position
Unknown
AA seq 1481 aa
MQRSPLEKASVVSKLFFSWTRPILRKGYRQRLESSDIYQIPSADSADYLSEKLEREWDRE
LASKKNPKLINALRRCFFWRFMFYGILLYLGEVTKAVQPLLLGRIIASYDPDNKEERSIA
IYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQL
VSFLSNNLNKFDEGLALAHFVWIVPLQVALLMGLIWELLQASAFCGLGFLIVLALFQAGL
GRMMMKYRDQRAGKINERLVITSEMIENIQSVKAYCWEEAMEKMIENLRQTELKLTRKAA
YVRYFNSSAFFFSGFFVVFLSVLPYALIKGIVLRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTEVVMENVTAFWEEGFGELFEKAKQNNSNRK
TSNGDDSLFFSNFSLLGTPVLKDINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEG
KIKHSGRISFCSQFSWIMPGTIKENIIFGVSYDECRYRSVIKACQLEEDISKFAEKDNIV
LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSIYFYGTFSELQNLRPDFSSKLMGYDSFDQFSAERRNS
ILTETLRRFSLEGDAPISRTETKKQSFKQTGEFGEKRKNSILNPINSIRKFSIVQKTPLQ
MNGIEEDSDEPLERRLSLVPDSEQGEVILPRISVISTGPTLQARRRQSVLNLMTQSVNQG
QSIHRKTAASTRKVSLAPQANLTELDIYSRRLSQETGLEISEEINEEDLKECFFDDMESI
PAVTTWNTYLRYITVHKSLIFVLIWCLVIFLAEVAASLVVLWFLGNTPPQDKGNSTYSRN
NSYAVIITRTSSYYVFYIYVGVADTLLAMGFFRGLPLVHTLITVSKILHHKMLHSVLQAP
MSTLNTLKAGGILNRFSKDIAILDDLLPLTIFDFIQLLLIVIGAIAVVAVLQPYIFVATV
PVIVAFIMLRAYFLQTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHK
ALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEGTVGIILTLAMNIM
STLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEEGKPTRSTTPYKNGQLLKVMIIENSHVK
KDDIWPSGGQMTIKDLTAKYTEGGNPILENISFSISPGQRVGLLGRTGSGKSTLLSAFLR
LLNTKGEIQIDGVSWDSVTLQQWRKAFGVIPQKVFIFSGTFRKNLDPYEQWSDQEIWKVA
DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV
TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLLNERSLFRQ
AISPSDRVKLFPHRNSSKCKSQPQIAALKEETEEEVQDTRL
NT seq 4446 nt   +upstreamnt  +downstreamnt
atgcagaggtcgcctctggaaaaggccagcgttgtctccaaactttttttcagctggacc
agaccaattttgaggaaaggatacagacagcgcctggaatcatcagatatataccaaatc
ccttctgctgattctgctgactatctatctgaaaaattggaaagagaatgggatagagag
ctggcttcaaagaaaaatcccaaactcattaatgcccttcggcgatgctttttctggaga
tttatgttctatggaatcttattatatttaggggaagtcaccaaagcagtacagcctctc
ttactgggaagaatcatagcttcctatgacccggataacaaggaggaacgctctatcgcg
atttatctaggcataggcttatgccttctctttatcgtgaggacactgctcttacaccca
gccatttttggccttcatcacattggaatgcagatgagaatagctatgtttagtttgatt
tataagaagactttaaagctgtcaagccgtgttctagataaaataagtattggacaactt
gttagtttcctttccaacaacctgaacaaatttgatgaaggacttgcattggcacatttc
gtgtggatcgttcctttgcaagtggcactcctcatggggctaatctgggagttgttacag
gcctctgccttctgtggacttggtttcctgatagtccttgccctttttcaggctgggcta
gggagaatgatgatgaagtacagagatcagagagctgggaagatcaatgaaagacttgtg
attacctcagaaatgattgaaaatatccaatctgttaaggcatactgctgggaagaagca
atggaaaaaatgattgaaaacctaagacaaacagaactgaaactaactcggaaggcagcc
tatgtgagatatttcaatagctcagccttcttcttctcaggattctttgtggtgttttta
tctgtgcttccctatgcactaatcaaaggaatcgtcctccgaaaaatattcacaaccata
tcattctgcattgttctgcgcatggcggtcactcggcaatttccctgggctgttcaaaca
tggtatgactctcttggagcaataaacaaaatacaggatttcttacaaaagcaagaatat
aagacattggaatataacttaacaactacagaagtagtgatggagaatgtaacagccttc
tgggaggagggatttggggaattatttgagaaagcaaaacaaaacaatagcaatagaaaa
acttctaatggtgatgacagcctcttcttcagtaatttctcacttcttggtactcctgtc
ctgaaagatattaatttcaagatagaaagaggacagttgttggcggttgctggatccact
ggagcaggcaagacttcacttctaatgatgattatgggagaactggagccttcagagggt
aaaattaagcacagtggaagaatttcattctgttctcagttttcctggattatgcctggc
accattaaagaaaatatcatctttggtgtttcctatgatgaatgtagatacagaagtgtc
atcaaagcatgccaactagaagaggacatctccaagtttgcagagaaagacaatatagtt
cttggagaaggtggaatcacactgagtggaggtcaacgagcaagaatttctttagcaaga
gcagtatacaaagatgctgatttgtatttattagactctccttttggatacctagatgtt
ttaacagaaaaagaaatatttgaaagctgtgtctgtaaactgatggctaacaaaactagg
attctggtcacttctaaaatggaacatttaaagaaagctgacaaaatattaattttacat
gaaggtagcatctatttttatgggacattttcagaactccaaaatctacggccagacttt
agctcaaaactcatgggatatgattctttcgaccaatttagtgcagaaagaagaaattca
atcctaactgagaccttacgccgtttctcattagaaggagatgctcctatctcccggacc
gaaacaaaaaaacaatcttttaaacagactggagagtttggggaaaaaaggaagaattct
attctcaatccaatcaactctatacgaaaattttccattgtccaaaagactcccttacaa
atgaatggcatcgaagaggattctgatgagcctttagagagaaggctgtccttagttcca
gattctgagcagggagaggtgatactccctcgcatcagcgtgatcagcactggccccacg
cttcaggcacgaaggaggcagtctgttctgaacctgatgacacaatcagttaaccaaggt
cagagcattcacagaaagacagcagcatccacacgaaaagtgtcactggcccctcaggca
aacttgactgaactggatatatattcaagaaggttatctcaagaaactggcttggaaata
agtgaagaaattaatgaagaagacttaaaggagtgcttttttgatgatatggagagcata
ccagcggtgactacatggaacacataccttcgatatattaccgtccacaagagcttaatt
tttgtgctaatttggtgcttggtaatttttctggctgaggtggctgcttctttggttgtg
ctgtggttccttggaaacactcctcctcaagacaaagggaatagtacttatagtagaaat
aacagctatgcagtgattatcaccagaaccagttcgtattatgtgttttacatttacgtg
ggagtagctgacactttgcttgctatgggattcttcagaggtctaccactggtgcatact
ctaatcacagtgtcgaaaattttacaccacaaaatgttacattctgttcttcaagcacct
atgtcaaccctcaacacgttgaaagcaggtgggattcttaatagattctccaaagatata
gcaattttggatgatcttctgcctcttaccatatttgacttcatccagttgttattaatt
gtgattggagctatagcagttgtcgcagttttacaaccctacatctttgttgcaacagtg
ccagtgatagtggcttttattatgttgagagcatatttcctccaaacctcacagcaactc
aaacaactggaatctgaaggcaggagtccaattttcactcatcttgttacaagcttaaaa
ggactatggacacttcgtgccttcggacggcagccttactttgaaactctgttccacaaa
gctctgaatttacatactgccaactggttcttgtatctttcaacactgcgctggttccaa
atgagaatagaaatgatttttgtcatcttcttcattgctgttaccttcatttccatttta
acaacaggagaaggagaaggaacagttggtattatcctgactttagccatgaatatcatg
agtacattgcagtgggctgtaaactccagcatagatgtggatagcttgatgcgatctgtg
agccgagtctttaagttcattgacatgccaacagaagaaggtaaacctaccaggtcaacc
acaccatacaagaatggccaactcttgaaagttatgattattgagaattcacacgtgaag
aaagatgacatctggccctcggggggccaaatgaccatcaaagatctcacagcaaaatac
acagaaggtggaaatcccatattagagaacatttccttctcaataagtcctggccagagg
gtgggcctcttgggaagaactggatcagggaagagtactttgttatcagcttttttgaga
ctactgaacactaaaggagaaatccagatcgatggtgtgtcttgggattcagtaactttg
caacagtggaggaaagcctttggagtgataccacagaaagtatttatcttttctggaaca
tttagaaaaaacttggatccctatgaacagtggagtgatcaagaaatatggaaagttgca
gatgaggttgggctcagatctgtgatagaacagtttcctgggaagcttgactttgtcctt
gtggatgggggctgtgtcctaagccatggccacaagcagttgatgtgtttggctagatct
gttctcagtaaggcgaagatcctgctgcttgatgaacccagtgctcatttggatccagta
acataccagataattagaagaactctaaaacaagcatttgctgactgcacagtaatcctc
tgtgaacacaggatagaagcaatgctggaatgccaacaatttttggtcatagaagagaac
aaagtgcggcagtatgattccatccagaaactgctgaatgagaggagcctcttccggcaa
gccatcagcccctccgacagggtgaagctctttccccaccggaactcaagcaagtgcaag
tctcagccccaaattgctgctctgaaagaggagacagaagaagaggtgcaagatacaagg
ctttag

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (19)   
   Pfam (19)   
All databases (25)   

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